Detailed information NTG1037015

Bioinformatically predicted

Overview

• Name: comYF
• Type: Machinery gene
• Locus tag: ACB354_RS00685
• Genome accession: NZ_CP167004
• Coordinates: 106792..107226 (+)
• Length: 144 a.a.
• NCBI ID: WP_002986542.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain Isolate 28
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 101792..112226

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACB354_RS00655 (ACB354_00655)	-	103461..103826 (+)	366	WP_002986560.1	DUF1033 family protein	-
ACB354_RS00660 (ACB354_00660)	comYA	103919..104857 (+)	939	WP_002986557.1	competence type IV pilus ATPase ComGA	Machinery gene
ACB354_RS00665 (ACB354_00665)	comYB	104793..105827 (+)	1035	WP_011184088.1	competence type IV pilus assembly protein ComGB	Machinery gene
ACB354_RS00670 (ACB354_00670)	comYC	105829..106155 (+)	327	WP_002986552.1	competence type IV pilus major pilin ComGC	Machinery gene
ACB354_RS00675 (ACB354_00675)	comGD	106130..106558 (+)	429	WP_011184089.1	competence type IV pilus minor pilin ComGD	-
ACB354_RS00680 (ACB354_00680)	comGE	106515..106799 (+)	285	WP_027968839.1	competence type IV pilus minor pilin ComGE	-
ACB354_RS00685 (ACB354_00685)	comYF	106792..107226 (+)	435	WP_002986542.1	competence type IV pilus minor pilin ComGF	Machinery gene
ACB354_RS00690 (ACB354_00690)	comGG	107210..107536 (+)	327	WP_002986539.1	competence type IV pilus minor pilin ComGG	-
ACB354_RS00695 (ACB354_00695)	comYH	107634..108587 (+)	954	WP_021340467.1	class I SAM-dependent methyltransferase	Machinery gene
ACB354_RS00700 (ACB354_00700)	-	108646..109842 (+)	1197	WP_002986533.1	acetate kinase	-
ACB354_RS00705 (ACB354_00705)	-	110029..110337 (+)	309	WP_011017251.1	hypothetical protein	-
ACB354_RS00710 (ACB354_00710)	proC	110420..111190 (-)	771	WP_011184092.1	pyrroline-5-carboxylate reductase	-

Sequence

Protein

• Length: 144 a.a.
• Molecular weight: 16573.20 Da
• Isoelectric Point: 10.3584

>NTDB_id=1037015 ACB354_RS00685 WP_002986542.1 106792..107226(+) (comYF) [Streptococcus pyogenes strain Isolate 28]
MSKQLSNIKAFTLLEALIALLVISGSLLVYQGLTQTLLKRSHYLARHDQDNWLLFSHQLREELSGARFYKVADNKLYVEK
GKKVLAFGQFKSHDFRKSASNGKGYQPMLFGISRSHIHIGQSQICITLKWKSGLERTFYYAFQD

Nucleotide

• Length: 435 bp

>NTDB_id=1037015 ACB354_RS00685 WP_002986542.1 106792..107226(+) (comYF) [Streptococcus pyogenes strain Isolate 28]
TTGAGTAAACAATTAAGTAACATAAAAGCTTTTACCCTTCTAGAGGCATTAATAGCCTTACTCGTGATATCAGGGTCTTT
ATTGGTTTATCAAGGTTTGACCCAAACCCTCCTTAAACGTAGCCATTATCTAGCCCGTCATGATCAAGACAATTGGCTCT
TATTTTCTCATCAATTGCGAGAGGAGTTAAGTGGAGCAAGATTTTACAAAGTAGCTGATAATAAACTATACGTTGAAAAG
GGAAAGAAAGTACTAGCTTTTGGCCAATTTAAAAGTCATGATTTCCGAAAATCAGCTAGTAATGGAAAAGGGTATCAACC
CATGTTATTTGGAATATCACGTAGTCATATTCACATAGGGCAGTCACAGATTTGCATTACTTTAAAGTGGAAAAGTGGGT
TAGAAAGGACTTTTTATTATGCCTTTCAAGACTAA

Domains

Predicted by InterproScan.

• Putative Competence protein ComGF (ComGF) (41-135)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comYF	Streptococcus mutans UA140	51.079	96.528	0.493
comYF	Streptococcus mutans UA159	50.36	96.528	0.486
comGF	Lactococcus lactis subsp. cremoris KW2	45.985	95.139	0.437
comGF/cglF	Streptococcus mitis NCTC 12261	44.03	93.056	0.41
comGF/cglF	Streptococcus pneumoniae Rx1	43.609	92.361	0.403
comGF/cglF	Streptococcus pneumoniae D39	43.609	92.361	0.403
comGF/cglF	Streptococcus pneumoniae R6	43.609	92.361	0.403
comGF/cglF	Streptococcus pneumoniae TIGR4	43.609	92.361	0.403
comGF/cglF	Streptococcus mitis SK321	42.857	92.361	0.396