Detailed information NTG0103469

Bioinformatically predicted

Overview

• Name: ruvB
• Type: Machinery gene
• Locus tag: STAB904_RS00330
• Genome accession: NZ_CP007241
• Coordinates: 53926..54924 (+)
• Length: 332 a.a.
• NCBI ID: WP_002986679.1
• Uniprot ID: A2RC05
• Organism: Streptococcus pyogenes strain 1E1
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 48926..59924

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
STAB904_RS00315 (STAB904_00340)	-	49928..51346 (+)	1419	WP_011888524.1	hypothetical protein	-
STAB904_RS00320 (STAB904_00345)	purB	51366..52658 (+)	1293	WP_038433842.1	adenylosuccinate lyase	-
STAB904_RS00325 (STAB904_00350)	comR	52789..53700 (+)	912	WP_002986681.1	transcriptional regulator Rgg4/ComR	Regulator
STAB904_RS09625	comS	53784..53879 (+)	96	WP_198462994.1	quorum-sensing system DWW-type pheromone	Regulator
STAB904_RS00330 (STAB904_00360)	ruvB	53926..54924 (+)	999	WP_002986679.1	Holliday junction branch migration DNA helicase RuvB	Machinery gene
STAB904_RS00335 (STAB904_00365)	-	55062..55499 (+)	438	WP_038433843.1	low molecular weight protein-tyrosine-phosphatase	-
STAB904_RS00340 (STAB904_00370)	-	55522..55923 (+)	402	WP_002986671.1	MORN repeat-containing protein	-
STAB904_RS00345 (STAB904_00375)	-	55920..57695 (+)	1776	WP_023612103.1	acyltransferase family protein	-

Sequence

Protein

• Length: 332 a.a.
• Molecular weight: 37565.11 Da
• Isoelectric Point: 5.3005

>NTDB_id=103469 STAB904_RS00330 WP_002986679.1 53926..54924(+) (ruvB) [Streptococcus pyogenes strain 1E1]
MARILDNNVMGNEEFSDRTLRPQYLHEYIGQDKVKEQFAIFIEAAKRRDESLDHVLLFGPPGLGKTTMAFVIANELGVNL
KQTSGPAVEKAGDLVAILNELEPGDILFIDEIHRMPMSVEEVLYSAMEDFYIDIMIGAGDTSRSIHLDLPPFTLIGATTR
AGMLSNPLRARFGITGHMEYYQEKDLTEIVERTATIFEIKIDHEAARKLACRSRGTPRIANRLLKRVRDYAQIIGDGIIT
AQITDRALTMLDVDREGLDYIDQKILRTMIEMYQGGPVGLGTLSVNIAEERNTVEEMYEPYLIQKGFLMRTRTGRVATQK
AYRHLGYPYQNT

Nucleotide

• Length: 999 bp

>NTDB_id=103469 STAB904_RS00330 WP_002986679.1 53926..54924(+) (ruvB) [Streptococcus pyogenes strain 1E1]
ATGGCTAGAATTTTAGACAATAATGTAATGGGAAATGAGGAGTTTTCGGATCGGACTCTTCGCCCTCAATATCTACACGA
ATATATTGGACAAGATAAAGTTAAGGAACAATTCGCTATTTTTATAGAAGCAGCTAAAAGACGTGACGAATCTTTAGACC
ATGTTTTATTATTTGGACCTCCAGGACTGGGAAAGACAACAATGGCATTTGTGATTGCCAATGAATTGGGAGTTAATTTA
AAGCAAACTTCAGGTCCTGCCGTTGAGAAAGCTGGAGATTTGGTAGCTATTTTAAATGAATTAGAACCAGGGGATATTTT
GTTTATTGATGAAATTCACCGCATGCCAATGTCTGTCGAGGAAGTACTATATAGTGCTATGGAAGACTTCTATATTGATA
TTATGATTGGCGCTGGAGATACTAGTCGTAGTATTCATTTGGATCTGCCTCCATTTACATTGATTGGTGCTACTACACGT
GCAGGCATGTTATCTAATCCCCTCAGAGCTCGTTTTGGTATCACTGGTCACATGGAATACTATCAAGAAAAGGATTTGAC
AGAGATTGTGGAGCGTACAGCTACTATTTTTGAAATAAAAATAGACCATGAAGCTGCACGGAAATTAGCTTGTCGCAGTA
GAGGAACGCCCCGCATTGCTAATCGATTACTAAAACGAGTGCGTGACTATGCTCAAATTATTGGTGATGGCATCATAACG
GCTCAAATAACTGATAGAGCTTTGACTATGTTAGATGTTGACCGCGAAGGTCTCGATTACATTGATCAGAAAATTTTACG
AACGATGATTGAGATGTATCAGGGAGGGCCAGTTGGTTTGGGGACATTATCTGTGAATATTGCCGAGGAGCGTAATACAG
TTGAAGAGATGTATGAACCCTACTTAATTCAAAAAGGCTTTCTCATGCGAACACGAACAGGTCGTGTAGCGACGCAAAAG
GCTTATCGTCATCTTGGCTATCCCTATCAAAACACTTAA

Domains

Predicted by InterProScan.

• RuvB C-terminal winged helix domain (WHD_RuvB) (256-325)

• RuvB AAA lid domain (AAA_lid_4) (181-254)

• Holliday junction DNA helicase RuvB P-loop domain (RuvB_N) (20-178)

3D structure

• AlphaFold DB: A2RC05

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ruvB	Streptococcus pneumoniae R6	84.848	99.398	0.843
ruvB	Streptococcus pneumoniae D39	84.848	99.398	0.843
ruvB	Streptococcus pneumoniae TIGR4	84.545	99.398	0.84
ruvB	Bacillus subtilis subsp. subtilis str. 168	58.824	97.289	0.572
ruvB	Helicobacter pylori 26695	48.936	99.096	0.485
ruvB	Synechocystis sp. PCC 6803	50.16	94.277	0.473