Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaH   Type   Regulator
Locus tag   AB4X21_RS04590 Genome accession   NZ_CP163380
Coordinates   883844..885205 (+) Length   453 a.a.
NCBI ID   WP_369088269.1    Uniprot ID   A0AB39LFF2
Organism   Streptococcus sp. CP1998     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 878844..890205
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AB4X21_RS04570 (AB4X21_04570) - 879166..881708 (+) 2543 Protein_848 M1 family metallopeptidase -
  AB4X21_RS04575 (AB4X21_04575) - 881765..882298 (-) 534 WP_129824198.1 biotin transporter BioY -
  AB4X21_RS04580 (AB4X21_04580) - 882505..883044 (+) 540 WP_369088268.1 hypothetical protein -
  AB4X21_RS04585 (AB4X21_04585) ciaR 883180..883860 (+) 681 WP_037607818.1 response regulator transcription factor Regulator
  AB4X21_RS04590 (AB4X21_04590) ciaH 883844..885205 (+) 1362 WP_369088269.1 sensor histidine kinase Regulator
  AB4X21_RS04595 (AB4X21_04595) - 885235..885615 (+) 381 WP_003003384.1 VOC family protein -
  AB4X21_RS04600 (AB4X21_04600) - 885725..887107 (+) 1383 WP_369088270.1 polysaccharide deacetylase family protein -
  AB4X21_RS04605 (AB4X21_04605) - 887150..888235 (-) 1086 WP_369088271.1 DEAD/DEAH box helicase -
  AB4X21_RS04610 (AB4X21_04610) - 888232..889212 (-) 981 WP_369088272.1 Gfo/Idh/MocA family protein -
  AB4X21_RS04615 (AB4X21_04615) - 889340..890050 (+) 711 WP_049472007.1 glycosyltransferase family 2 protein -

Sequence

Protein


Download         Length: 453 a.a.        Molecular weight: 52066.55 Da        Isoelectric Point: 6.5335

>NTDB_id=1029433 AB4X21_RS04590 WP_369088269.1 883844..885205(+) (ciaH) [Streptococcus sp. CP1998]
MLTRIKKTVGEDDFSYFIRYFGLFTLIFSAMTLIIIQVMRSSLYTTVDENLKTLSQDPYSLVAIAYRDQRQSNNKVENND
HEMMIPEHDKSEPKGDVTSNTTVVLLNKKYENLTTGNGFLNFKTVTFGRKLLNKVSQLQITNSYGKKESYRAYMAELSLS
DDESDSDIKYAVVMTNISQLEQTSEEHESQIALVMICFWGISLFASLFLARLSVKPLLEIMQKQKAFVENASHELRTPLA
VLQNRLETLFRKPEATIMESSENIASSLDEVRNMKLLTTNLLNIARRDDGLKPEMEDIEPSFFDQTFSNFEIIAEENDKI
FRGDNQVDKVICSDRTLLKQLMTILYDNALKYTDEDGEIQFEVQLKDKNLLLRVLDNGPGIRDEDKKRIFDRFYRVDKAR
TRQKGGFGLGLSLAKQIVEAFKGTIQVKDNKPKGTIFEVKLSIKTESRKKNRS

Nucleotide


Download         Length: 1362 bp        

>NTDB_id=1029433 AB4X21_RS04590 WP_369088269.1 883844..885205(+) (ciaH) [Streptococcus sp. CP1998]
ATGCTAACCAGAATTAAGAAAACCGTTGGGGAAGATGATTTTTCCTACTTCATCCGATATTTTGGGCTCTTTACTTTGAT
ATTCTCAGCCATGACCCTGATTATCATCCAGGTCATGCGCTCGAGTCTCTATACAACTGTAGATGAAAACCTCAAGACTC
TCAGTCAGGATCCCTACTCGCTTGTAGCGATTGCTTATCGAGACCAGCGACAATCGAATAATAAAGTAGAAAATAACGAT
CATGAGATGATGATCCCAGAACATGATAAATCAGAACCTAAAGGGGATGTCACATCGAATACCACTGTTGTTTTGCTCAA
TAAAAAATATGAAAACTTGACAACCGGTAATGGTTTTTTAAACTTCAAAACCGTGACGTTTGGTCGAAAGCTCCTCAACA
AGGTTTCCCAGCTTCAAATTACAAATAGCTATGGGAAAAAAGAAAGTTACCGGGCCTATATGGCAGAGTTGAGTTTATCT
GATGATGAAAGTGATAGTGATATCAAGTATGCGGTTGTCATGACCAATATCAGTCAGCTAGAGCAGACCAGTGAAGAGCA
CGAAAGCCAAATCGCCCTTGTCATGATCTGCTTCTGGGGAATCTCGTTATTTGCTAGTCTCTTCTTAGCACGTCTCAGCG
TCAAGCCCCTTCTTGAGATTATGCAAAAGCAAAAGGCTTTCGTGGAAAATGCTTCCCATGAGTTGCGGACGCCTTTAGCA
GTTCTGCAAAATCGCCTCGAAACGCTTTTTAGAAAGCCTGAAGCGACCATTATGGAATCGAGTGAGAATATTGCATCCAG
CTTGGATGAAGTTCGAAATATGAAGCTCTTGACCACCAACCTTCTTAATATTGCCCGAAGAGATGACGGCTTGAAGCCGG
AGATGGAAGATATCGAACCAAGCTTTTTCGATCAGACCTTCTCGAATTTTGAGATCATTGCGGAAGAAAATGATAAAATC
TTCCGAGGAGACAATCAGGTGGACAAAGTCATTTGTTCTGATAGAACGCTCCTCAAGCAGTTGATGACCATTCTCTATGA
CAATGCCTTGAAATATACCGATGAAGATGGCGAGATCCAATTCGAAGTTCAATTGAAGGATAAAAATCTTCTTTTGAGAG
TACTGGATAATGGTCCAGGGATTCGAGATGAGGATAAGAAACGGATTTTTGATCGTTTTTACCGGGTCGACAAGGCCAGA
ACCCGTCAGAAAGGTGGTTTTGGTTTGGGGTTATCCCTCGCTAAGCAGATTGTAGAAGCTTTCAAAGGGACCATTCAAGT
CAAAGATAATAAACCAAAAGGGACCATCTTTGAAGTGAAATTATCCATTAAGACGGAAAGTCGTAAAAAAAATCGTTCAT
AA

Domains

Predicted by InterproScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(225-290)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(334-442)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaH Streptococcus pneumoniae Rx1

60

99.338

0.596
  ciaH Streptococcus pneumoniae D39

60

99.338

0.596
  ciaH Streptococcus pneumoniae R6

60

99.338

0.596
  ciaH Streptococcus pneumoniae TIGR4

60

99.338

0.596
  ciaH Streptococcus mutans UA159

50.45

98.013

0.494

Multiple sequence alignment