Detailed information    

insolico Bioinformatically predicted

Overview

Name   amiA3   Type   Regulator
Locus tag   AB4X21_RS03830 Genome accession   NZ_CP163380
Coordinates   725547..727514 (+) Length   655 a.a.
NCBI ID   WP_369088216.1    Uniprot ID   A0AB39LFB7
Organism   Streptococcus sp. CP1998     
Function   binding to XIP (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Genomic island 717274..747595 725547..727514 within 0


Gene organization within MGE regions


Location: 717274..747595
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AB4X21_RS03780 (AB4X21_03780) - 717274..718476 (+) 1203 WP_369088211.1 ABC transporter permease -
  AB4X21_RS03785 (AB4X21_03785) - 718576..719055 (+) 480 WP_223325328.1 NUDIX hydrolase -
  AB4X21_RS03790 (AB4X21_03790) - 719063..719791 (+) 729 WP_049473163.1 GNAT family N-acetyltransferase -
  AB4X21_RS03795 (AB4X21_03795) - 719833..720717 (+) 885 WP_369088212.1 putative PEP-binding protein -
  AB4X21_RS03800 (AB4X21_03800) - 720677..721117 (+) 441 WP_369088213.1 ASCH domain-containing protein -
  AB4X21_RS03805 (AB4X21_03805) glmU 721521..722900 (+) 1380 WP_369088214.1 bifunctional UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase GlmU -
  AB4X21_RS03810 (AB4X21_03810) - 722910..723455 (+) 546 WP_003002456.1 NUDIX hydrolase -
  AB4X21_RS03815 (AB4X21_03815) macP 723467..723802 (+) 336 WP_070594427.1 cell wall synthase accessory phosphoprotein MacP -
  AB4X21_RS03820 (AB4X21_03820) - 723827..724519 (+) 693 WP_369088215.1 5'-methylthioadenosine/adenosylhomocysteine nucleosidase -
  AB4X21_RS03825 (AB4X21_03825) nth 724658..725281 (+) 624 WP_003006251.1 endonuclease III -
  AB4X21_RS03830 (AB4X21_03830) amiA3 725547..727514 (+) 1968 WP_369088216.1 peptide ABC transporter substrate-binding protein Regulator
  AB4X21_RS03835 (AB4X21_03835) - 727706..727798 (-) 93 Protein_703 VOC family protein -
  AB4X21_RS03840 (AB4X21_03840) - 727906..728544 (+) 639 WP_023917595.1 hypothetical protein -
  AB4X21_RS03845 (AB4X21_03845) - 728779..729165 (-) 387 WP_004219638.1 VOC family protein -
  AB4X21_RS03850 (AB4X21_03850) - 729177..730004 (-) 828 WP_049522944.1 exodeoxyribonuclease III -
  AB4X21_RS03855 (AB4X21_03855) - 730383..730697 (+) 315 WP_000420682.1 YdcP family protein -
  AB4X21_RS03860 (AB4X21_03860) - 730713..731099 (+) 387 WP_000985015.1 YdcP family protein -
  AB4X21_RS03865 (AB4X21_03865) - 731128..732513 (+) 1386 WP_000813488.1 FtsK/SpoIIIE domain-containing protein -
  AB4X21_RS03870 (AB4X21_03870) - 732516..732668 (+) 153 WP_000879507.1 hypothetical protein -
  AB4X21_RS03875 (AB4X21_03875) mobT 732691..733911 (+) 1221 WP_369088217.1 MobT family relaxase -
  AB4X21_RS03880 (AB4X21_03880) - 733901..734068 (+) 168 WP_000502600.1 MLS leader peptide -
  AB4X21_RS03885 (AB4X21_03885) - 734117..734200 (+) 84 WP_001814874.1 23S rRNA methyltransferase attenuation leader peptide -
  AB4X21_RS03890 (AB4X21_03890) erm(B) 734325..735062 (+) 738 WP_001038795.1 23S rRNA (adenine(2058)-N(6))-methyltransferase Erm(B) -
  AB4X21_RS03895 (AB4X21_03895) - 735319..736566 (-) 1248 WP_000019067.1 ISL3 family transposase -
  AB4X21_RS03900 (AB4X21_03900) - 736746..736967 (+) 222 WP_001009056.1 hypothetical protein -
  AB4X21_RS03905 (AB4X21_03905) - 737084..737581 (+) 498 WP_000342539.1 antirestriction protein ArdA -
  AB4X21_RS03910 (AB4X21_03910) - 737670..738062 (+) 393 WP_000723888.1 conjugal transfer protein -
  AB4X21_RS03915 (AB4X21_03915) - 738046..740493 (+) 2448 WP_272071924.1 ATP-binding protein -
  AB4X21_RS03920 (AB4X21_03920) - 740496..742673 (+) 2178 WP_000804748.1 CD3337/EF1877 family mobilome membrane protein -
  AB4X21_RS03925 (AB4X21_03925) - 742670..743671 (+) 1002 WP_000769868.1 lysozyme family protein -
  AB4X21_RS03930 (AB4X21_03930) - 743668..744600 (+) 933 WP_001224318.1 conjugal transfer protein -
  AB4X21_RS03935 (AB4X21_03935) - 744914..744961 (+) 48 Protein_723 hypothetical protein -
  AB4X21_RS03940 (AB4X21_03940) tet(M) 744977..746896 (+) 1920 WP_369088218.1 tetracycline resistance ribosomal protection protein Tet(M) -
  AB4X21_RS03945 (AB4X21_03945) - 747015..747182 (+) 168 WP_000336323.1 cysteine-rich KTR domain-containing protein -
  AB4X21_RS03950 (AB4X21_03950) - 747242..747595 (-) 354 WP_001227347.1 helix-turn-helix transcriptional regulator -

Sequence

Protein


Download         Length: 655 a.a.        Molecular weight: 72172.42 Da        Isoelectric Point: 5.6412

>NTDB_id=1029425 AB4X21_RS03830 WP_369088216.1 725547..727514(+) (amiA3) [Streptococcus sp. CP1998]
MKAKKLLALAGVSVAGAFLLTACGGSSSNQATYSFVYSADPNTLDYIAATRTTTSDVTSNLVDGLLENDRYGNFVPSLAE
DWTVSEDGLTYTYKLRKDAKWYTSEGEEYGAVTAQDFVTGIKHAVESKSEGLFLIQNSIKGLDAYVKGETKDFNTVGVKA
LDDHTIQYTLVRPESFWNSKTTSGVLFPVNADFLKSQGKDFGSLKPSSILYNGPYYLKSLTSKSEIELVKNKDYYDAKNV
HIDNVKLTFNDGSNPDSIIKNFEKGQYSFASVMPNSSTYKSVKKNFGDNIVYGLQLGTSYYLGFNLDRQKYDHTAKTTDE
QKASTKKAILNKDFRQAVNFGFDRKSYAAQVSGSDAAENTLRSTLVPPTYVQVNGEDFGKVVEKQLVTYGDQWKGVSLAD
GQTSLYNPEKAKASFAKAKAELQKQGVQFPIHLDYIVSQVDNSMVQQASSFKQSVESALGADNVVVDLQKVSDDDFQNIT
YFSDTAAARDYDISGGGWAPDYQDPSTYLESISPVNGSVFYYLGIDAGSNNPAIATVGLDQYANMLKDADAELLDQGKRY
EKYAAAQAWLTDSSITLPTVSNGGAPMLQRTVPYSRAASWVGTKGTGTFYKYLEMSKDVVTTKDFNKAKEEWLKKKAESN
KKAQEDLKDHIEKKK

Nucleotide


Download         Length: 1968 bp        

>NTDB_id=1029425 AB4X21_RS03830 WP_369088216.1 725547..727514(+) (amiA3) [Streptococcus sp. CP1998]
ATGAAAGCAAAAAAACTGTTAGCTCTTGCAGGAGTTTCTGTTGCAGGTGCCTTTCTCTTAACAGCATGTGGTGGTAGCAG
CAGCAATCAAGCAACCTACTCATTTGTCTATTCAGCAGATCCAAATACCTTGGACTATATTGCTGCAACTCGTACGACTA
CTTCAGATGTCACAAGTAACCTTGTAGATGGTCTTCTTGAAAACGACCGATACGGAAACTTTGTGCCAAGTCTAGCAGAA
GATTGGACTGTCTCTGAAGATGGATTGACCTATACTTACAAACTTCGTAAGGATGCCAAATGGTATACGAGTGAAGGAGA
AGAATATGGTGCTGTAACGGCTCAAGACTTTGTTACAGGGATCAAACACGCAGTTGAGTCTAAATCAGAAGGTCTCTTCT
TGATTCAAAATTCGATCAAAGGTTTGGATGCCTACGTAAAAGGGGAAACCAAAGACTTTAACACAGTTGGAGTCAAAGCC
TTAGATGACCACACCATCCAATATACTTTGGTCCGTCCAGAAAGCTTCTGGAACTCAAAAACAACCTCAGGTGTTCTTTT
CCCAGTCAATGCAGATTTCTTGAAATCTCAAGGAAAAGATTTTGGTTCTTTGAAACCTAGCAGCATCTTATACAATGGTC
CATATTACTTGAAATCATTGACTTCAAAATCTGAGATTGAATTGGTCAAGAACAAAGACTATTACGATGCGAAAAATGTT
CATATCGACAATGTCAAATTGACCTTTAACGATGGATCAAACCCAGATTCTATCATTAAGAACTTTGAAAAAGGTCAATA
TTCCTTTGCATCTGTTATGCCAAACAGTTCGACTTATAAGAGTGTCAAGAAAAACTTTGGTGACAACATTGTCTATGGTT
TGCAATTGGGAACATCCTACTATCTTGGATTCAACTTGGACCGTCAAAAGTATGACCACACAGCCAAAACAACGGATGAA
CAAAAAGCTTCTACCAAGAAAGCAATTCTGAACAAGGACTTCCGTCAAGCGGTGAACTTTGGCTTTGACCGCAAATCATA
TGCGGCACAAGTATCTGGATCTGATGCGGCTGAAAATACCCTTCGTAGCACTTTGGTGCCACCAACTTATGTCCAAGTCA
ATGGAGAAGATTTTGGTAAAGTCGTTGAAAAACAATTGGTTACCTATGGGGATCAATGGAAGGGTGTGAGCCTGGCCGAT
GGTCAAACGAGCCTTTACAATCCAGAAAAAGCCAAAGCTTCATTTGCAAAAGCCAAAGCTGAATTGCAAAAACAAGGAGT
TCAATTCCCAATTCATTTGGACTATATTGTCAGCCAAGTGGACAACAGCATGGTCCAACAAGCGAGTTCCTTCAAACAAT
CCGTAGAGTCAGCGCTTGGTGCAGACAATGTCGTTGTGGACCTTCAAAAGGTATCGGATGATGATTTCCAAAATATCACC
TACTTCAGCGATACAGCGGCTGCGAGAGATTACGATATCTCAGGCGGTGGTTGGGCTCCTGACTACCAAGACCCATCGAC
TTATCTTGAAAGTATCAGCCCAGTAAATGGTTCTGTCTTCTACTATCTTGGTATTGATGCAGGTTCAAACAATCCAGCCA
TTGCAACAGTTGGTTTGGATCAATACGCTAACATGTTGAAAGACGCCGATGCTGAATTGTTGGATCAAGGAAAACGCTAT
GAAAAATATGCAGCAGCGCAAGCTTGGTTGACAGATAGCTCGATTACGCTTCCAACTGTCTCAAATGGTGGTGCTCCAAT
GCTTCAACGGACCGTGCCATACAGCCGTGCTGCTTCATGGGTAGGTACTAAAGGAACAGGAACATTCTACAAATACCTTG
AAATGTCGAAAGATGTTGTCACCACAAAAGACTTTAACAAGGCCAAAGAAGAATGGTTGAAGAAAAAAGCAGAATCCAAT
AAAAAAGCTCAAGAAGATCTCAAAGATCACATTGAGAAGAAAAAATAA

Domains

Predicted by InterproScan.

Bacterial extracellular solute-binding proteins, family 5 Middle (SBP_bac_5)

(74-512)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  amiA3 Streptococcus thermophilus LMD-9

53.636

100

0.54
  amiA3 Streptococcus thermophilus LMG 18311

53.485

100

0.539
  amiA Streptococcus salivarius strain HSISS4

52.352

100

0.527

Multiple sequence alignment