Detailed information NTG1024263

Bioinformatically predicted

Overview

• Name: ruvB
• Type: Machinery gene
• Locus tag: DQN36_RS00335
• Genome accession: NZ_LS483425
• Coordinates: 53984..54982 (+)
• Length: 332 a.a.
• NCBI ID: WP_002986679.1
• Uniprot ID: A2RC05
• Organism: Streptococcus pyogenes strain NCTC13737
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 48984..59982

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQN36_RS00320 (NCTC13737_00064)	-	49985..51403 (+)	1419	WP_011888524.1	hypothetical protein	-
DQN36_RS00325 (NCTC13737_00065)	purB	51423..52715 (+)	1293	WP_111703941.1	adenylosuccinate lyase	-
DQN36_RS00330 (NCTC13737_00066)	comR	52847..53758 (+)	912	WP_002986681.1	transcriptional regulator Rgg4/ComR	Regulator
DQN36_RS09320 (NCTC13737_00067)	comS	53842..53937 (+)	96	WP_198462994.1	quorum-sensing system DWW-type pheromone	Regulator
DQN36_RS00335 (NCTC13737_00068)	ruvB	53984..54982 (+)	999	WP_002986679.1	Holliday junction branch migration DNA helicase RuvB	Machinery gene
DQN36_RS00340 (NCTC13737_00069)	-	55120..55557 (+)	438	WP_020904819.1	low molecular weight protein-tyrosine-phosphatase	-
DQN36_RS00345 (NCTC13737_00070)	-	55581..55982 (+)	402	WP_002986671.1	MORN repeat-containing protein	-
DQN36_RS00350 (NCTC13737_00071)	-	55979..57754 (+)	1776	WP_111703942.1	acyltransferase family protein	-

Sequence

Protein

• Length: 332 a.a.
• Molecular weight: 37565.11 Da
• Isoelectric Point: 5.3005

>NTDB_id=1024263 DQN36_RS00335 WP_002986679.1 53984..54982(+) (ruvB) [Streptococcus pyogenes strain NCTC13737]
MARILDNNVMGNEEFSDRTLRPQYLHEYIGQDKVKEQFAIFIEAAKRRDESLDHVLLFGPPGLGKTTMAFVIANELGVNL
KQTSGPAVEKAGDLVAILNELEPGDILFIDEIHRMPMSVEEVLYSAMEDFYIDIMIGAGDTSRSIHLDLPPFTLIGATTR
AGMLSNPLRARFGITGHMEYYQEKDLTEIVERTATIFEIKIDHEAARKLACRSRGTPRIANRLLKRVRDYAQIIGDGIIT
AQITDRALTMLDVDREGLDYIDQKILRTMIEMYQGGPVGLGTLSVNIAEERNTVEEMYEPYLIQKGFLMRTRTGRVATQK
AYRHLGYPYQNT

Nucleotide

• Length: 999 bp

>NTDB_id=1024263 DQN36_RS00335 WP_002986679.1 53984..54982(+) (ruvB) [Streptococcus pyogenes strain NCTC13737]
ATGGCTAGAATTTTAGACAATAATGTAATGGGAAATGAGGAGTTTTCGGATCGGACTCTTCGCCCTCAATATCTACACGA
ATATATTGGACAAGATAAAGTTAAGGAACAATTCGCTATTTTTATAGAAGCAGCTAAAAGACGTGACGAATCTTTAGACC
ATGTTTTATTATTTGGACCTCCAGGACTGGGAAAAACAACAATGGCATTTGTGATTGCCAATGAATTGGGAGTTAATTTA
AAGCAAACTTCAGGTCCTGCTGTTGAGAAAGCTGGAGATTTGGTAGCTATTTTAAATGAATTAGAACCAGGGGATATTTT
GTTTATTGATGAAATTCACCGCATGCCAATGTCTGTCGAGGAAGTACTATATAGTGCTATGGAAGACTTCTATATTGATA
TTATGATTGGCGCTGGAGATACTAGTCGTAGTATTCATTTGGATCTGCCTCCATTTACATTGATTGGTGCTACTACACGT
GCAGGCATGTTATCTAATCCCCTCAGAGCTCGTTTTGGTATCACTGGTCACATGGAATACTATCAAGAAAAGGATTTGAC
AGAGATTGTGGAGCGTACAGCTACTATTTTTGAAATAAAAATAGACCATGAAGCTGCACGGAAATTAGCTTGTCGCAGTA
GAGGAACGCCCCGCATTGCTAATCGATTACTAAAACGAGTGCGTGACTATGCTCAAATTATTGGTGATGGCATCATAACG
GCTCAAATAACTGATAGAGCTTTGACTATGTTAGATGTTGACCGCGAAGGTCTCGATTACATTGATCAGAAAATTTTACG
AACGATGATTGAGATGTATCAGGGAGGACCAGTTGGTTTGGGGACATTATCTGTGAATATTGCCGAGGAGCGTAATACAG
TTGAAGAGATGTATGAACCCTACTTAATTCAAAAAGGCTTTCTCATGCGAACACGAACAGGTCGTGTAGCGACGCAAAAG
GCTTATCGTCATCTTGGCTATCCCTATCAAAACACTTAA

Domains

Predicted by InterProScan.

• RuvB C-terminal winged helix domain (WHD_RuvB) (256-325)

• RuvB AAA lid domain (AAA_lid_4) (181-254)

• Holliday junction DNA helicase RuvB P-loop domain (RuvB_N) (20-178)

3D structure

• AlphaFold DB: A2RC05

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ruvB	Streptococcus pneumoniae R6	84.848	99.398	0.843
ruvB	Streptococcus pneumoniae D39	84.848	99.398	0.843
ruvB	Streptococcus pneumoniae TIGR4	84.545	99.398	0.84
ruvB	Bacillus subtilis subsp. subtilis str. 168	58.824	97.289	0.572
ruvB	Helicobacter pylori 26695	48.936	99.096	0.485
ruvB	Synechocystis sp. PCC 6803	50.16	94.277	0.473