NTDB

Overview

Name	ruvA	Type	Machinery gene
Locus tag	DQN31_RS08580	Genome accession	NZ_LS483421
Coordinates	1707377..1707973 (-)	Length	198 a.a.
NCBI ID	WP_002992186.1	Uniprot ID	P0DF49
Organism	Streptococcus pyogenes strain NCTC10877
Function	homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 1702377..1712973

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQN31_RS08545 (NCTC10877_01687)	-	1702437..1702742 (-)	306	WP_002982199.1	DUF1292 domain-containing protein	-
DQN31_RS08550 (NCTC10877_01688)	ruvX	1702754..1703173 (-)	420	WP_002982196.1	Holliday junction resolvase RuvX	-
DQN31_RS08555 (NCTC10877_01689)	-	1703170..1703439 (-)	270	WP_002982194.1	IreB family regulatory phosphoprotein	-
DQN31_RS08560 (NCTC10877_01690)	spx	1703553..1703951 (-)	399	WP_002982188.1	transcriptional regulator Spx	-
DQN31_RS08565 (NCTC10877_01691)	recA	1704242..1705378 (-)	1137	WP_014407932.1	recombinase RecA	-
DQN31_RS08570 (NCTC10877_01692)	cinA	1705467..1706738 (-)	1272	WP_011285266.1	competence/damage-inducible protein A	Machinery gene
DQN31_RS08575 (NCTC10877_01693)	-	1706807..1707367 (-)	561	WP_010922755.1	DNA-3-methyladenine glycosylase I	-
DQN31_RS08580 (NCTC10877_01694)	ruvA	1707377..1707973 (-)	597	WP_002992186.1	Holliday junction branch migration protein RuvA	Machinery gene
DQN31_RS08585 (NCTC10877_01695)	-	1707975..1709195 (-)	1221	WP_014407934.1	MDR family MFS transporter	-
DQN31_RS08590 (NCTC10877_01696)	hexB	1709206..1711188 (-)	1983	WP_014407935.1	DNA mismatch repair endonuclease MutL	Machinery gene
DQN31_RS08595 (NCTC10877_01697)	-	1711283..1712428 (-)	1146	WP_041174352.1	tyrosine-type recombinase/integrase	-

Sequence

Protein

Download Length: 198 a.a. Molecular weight: 21879.26 Da Isoelectric Point: 6.8838

                                >NTDB_id=1024254 DQN31_RS08580 WP_002992186.1 1707377..1707973(-) (ruvA) [Streptococcus pyogenes strain NCTC10877]

MYDYIKGQLTKITAKYIVVEANGLGYMINVANPYSFTDSVNQLVTIYLHQVIREDAHLLFGFHTEDEKDVFLKLISVSGI

GPTTALAIVAVDDNEGLVNAIDNSDIKYLMKFPKIGKKTAQQMVLDLAGKFVEAPQETGHTKARSNKAGNTQLDEAIEAL

LALGYKAKELKKIRAFFEGTSETAEQYIKSALKLLMKG

Nucleotide

Download Length: 597 bp

                                >NTDB_id=1024254 DQN31_RS08580 WP_002992186.1 1707377..1707973(-) (ruvA) [Streptococcus pyogenes strain NCTC10877]

ATGTACGATTATATTAAAGGTCAATTGACCAAAATTACGGCAAAATACATTGTCGTTGAAGCTAATGGATTGGGCTACAT

GATTAATGTTGCCAATCCTTATAGCTTTACAGATAGTGTCAACCAATTGGTAACCATTTATCTGCATCAAGTGATTCGTG

AGGATGCTCACCTGTTGTTTGGGTTTCACACGGAAGATGAAAAAGATGTTTTTCTGAAATTAATTTCTGTATCAGGTATT

GGTCCGACAACAGCTCTTGCTATTGTGGCAGTTGATGATAATGAGGGACTTGTGAATGCCATTGATAACAGTGACATTAA

GTACCTAATGAAATTTCCTAAAATTGGTAAAAAAACAGCGCAGCAAATGGTTCTTGACTTAGCTGGCAAATTTGTGGAGG

CTCCACAAGAGACTGGTCATACCAAAGCGCGCAGCAATAAAGCAGGCAATACTCAACTGGACGAAGCGATTGAAGCCCTC

CTTGCTCTCGGTTATAAAGCAAAAGAGCTGAAAAAAATTCGTGCCTTCTTTGAGGGGACCTCTGAGACGGCAGAGCAATA

CATCAAATCAGCATTGAAACTGTTAATGAAAGGGTAG

Domains

Predicted by InterProScan.

RuvA N terminal domain (RuvA_N)

(1-61)

Helix-hairpin-helix domain (HHH_5)

(71-127)

RuvA, C-terminal domain (RuvA_C)

(152-196)

Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.

3D structure

Source	ID	Structure
AlphaFold DB	P0DF49

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.

Visualization of predicted probability:

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	H_a-value
ruvA	Streptococcus pneumoniae TIGR4	65.99	99.495	0.657
ruvA	Streptococcus pneumoniae R6	65.99	99.495	0.657
ruvA	Streptococcus pneumoniae D39	65.99	99.495	0.657
ruvA	Bacillus subtilis subsp. subtilis str. 168	40.887	100	0.419

Detailed information NTG1024254