Detailed information
Bioinformatically predicted
Overview
| Name | ciaR | Type | Regulator |
| Locus tag | AB1395_RS05055 | Genome accession | NZ_CP161815 |
| Coordinates | 984955..985626 (-) | Length | 223 a.a. |
| NCBI ID | WP_218654371.1 | Uniprot ID | - |
| Organism | Streptococcus pluranimalium strain SS-15 | ||
| Function | repress competence development (predicted from homology) Competence regulation |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| Prophage | 961743..994955 | 984955..985626 | within | 0 |
Gene organization within MGE regions
Location: 961743..994955
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| AB1395_RS04940 (AB1395_04940) | - | 961743..963479 (-) | 1737 | WP_104967867.1 | ABC transporter ATP-binding protein | - |
| AB1395_RS04945 (AB1395_04945) | - | 963476..965212 (-) | 1737 | WP_367784161.1 | ABC transporter ATP-binding protein | - |
| AB1395_RS04950 (AB1395_04950) | - | 965230..965835 (-) | 606 | WP_367784163.1 | lysozyme family protein | - |
| AB1395_RS04955 (AB1395_04955) | - | 965835..966809 (-) | 975 | WP_367784165.1 | nucleoid-associated protein | - |
| AB1395_RS04960 (AB1395_04960) | glyA | 966814..968070 (-) | 1257 | WP_367784167.1 | serine hydroxymethyltransferase | - |
| AB1395_RS04965 (AB1395_04965) | - | 968081..968512 (-) | 432 | WP_104967871.1 | GNAT family N-acetyltransferase | - |
| AB1395_RS04970 (AB1395_04970) | - | 968525..969124 (-) | 600 | WP_104967872.1 | L-threonylcarbamoyladenylate synthase | - |
| AB1395_RS04975 (AB1395_04975) | prmC | 969121..969948 (-) | 828 | WP_218654364.1 | peptide chain release factor N(5)-glutamine methyltransferase | - |
| AB1395_RS04980 (AB1395_04980) | prfA | 969948..971027 (-) | 1080 | WP_218654365.1 | peptide chain release factor 1 | - |
| AB1395_RS04985 (AB1395_04985) | - | 971061..971639 (-) | 579 | WP_104967875.1 | thymidine kinase | - |
| AB1395_RS04990 (AB1395_04990) | - | 972074..972259 (+) | 186 | WP_115130289.1 | 4-oxalocrotonate tautomerase | - |
| AB1395_RS04995 (AB1395_04995) | - | 972268..973206 (+) | 939 | WP_367784171.1 | FAD:protein FMN transferase | - |
| AB1395_RS05000 (AB1395_05000) | - | 973242..973580 (-) | 339 | WP_104967878.1 | ATP cone domain-containing protein | - |
| AB1395_RS05005 (AB1395_05005) | nox | 973710..975077 (-) | 1368 | WP_115130291.1 | H2O-forming NADH oxidase | - |
| AB1395_RS05010 (AB1395_05010) | - | 975458..976414 (-) | 957 | WP_218654367.1 | ABC transporter permease | - |
| AB1395_RS05015 (AB1395_05015) | - | 976417..977478 (-) | 1062 | WP_104967881.1 | ABC transporter permease | - |
| AB1395_RS05020 (AB1395_05020) | - | 977471..979003 (-) | 1533 | WP_104967882.1 | ABC transporter ATP-binding protein | - |
| AB1395_RS05025 (AB1395_05025) | - | 979145..980194 (-) | 1050 | WP_278025301.1 | BMP family protein | - |
| AB1395_RS05030 (AB1395_05030) | - | 980267..980656 (-) | 390 | WP_278025302.1 | cytidine deaminase | - |
| AB1395_RS05035 (AB1395_05035) | - | 981250..981837 (-) | 588 | WP_278025303.1 | class I SAM-dependent methyltransferase | - |
| AB1395_RS05040 (AB1395_05040) | coaA | 981964..982884 (+) | 921 | WP_316606434.1 | type I pantothenate kinase | - |
| AB1395_RS05045 (AB1395_05045) | rpsT | 982937..983185 (+) | 249 | WP_104967887.1 | 30S ribosomal protein S20 | - |
| AB1395_RS05050 (AB1395_05050) | ciaH | 983658..984962 (-) | 1305 | WP_218654370.1 | cell wall metabolism sensor histidine kinase WalK | Regulator |
| AB1395_RS05055 (AB1395_05055) | ciaR | 984955..985626 (-) | 672 | WP_218654371.1 | response regulator transcription factor | Regulator |
| AB1395_RS05060 (AB1395_05060) | - | 985872..988406 (-) | 2535 | WP_218654372.1 | M1 family metallopeptidase | - |
| AB1395_RS05065 (AB1395_05065) | phoU | 988528..989181 (-) | 654 | WP_115130300.1 | phosphate signaling complex protein PhoU | - |
| AB1395_RS05070 (AB1395_05070) | pstB | 989207..989965 (-) | 759 | WP_104967892.1 | phosphate ABC transporter ATP-binding protein PstB | - |
| AB1395_RS05075 (AB1395_05075) | pstB | 989978..990781 (-) | 804 | WP_104967893.1 | phosphate ABC transporter ATP-binding protein PstB | - |
| AB1395_RS05080 (AB1395_05080) | pstA | 990794..991681 (-) | 888 | WP_104967894.1 | phosphate ABC transporter permease PstA | - |
| AB1395_RS05085 (AB1395_05085) | pstC | 991671..992606 (-) | 936 | WP_104967895.1 | phosphate ABC transporter permease subunit PstC | - |
| AB1395_RS05090 (AB1395_05090) | - | 992616..993482 (-) | 867 | WP_104967896.1 | phosphate ABC transporter substrate-binding protein PstS | - |
| AB1395_RS05095 (AB1395_05095) | - | 993633..994955 (-) | 1323 | WP_367784179.1 | RsmF rRNA methyltransferase first C-terminal domain-containing protein | - |
Sequence
Protein
Download Length: 223 a.a. Molecular weight: 25404.29 Da Isoelectric Point: 4.5086
>NTDB_id=1022589 AB1395_RS05055 WP_218654371.1 984955..985626(-) (ciaR) [Streptococcus pluranimalium strain SS-15]
MIKLLLVEDDLSLSNSVFDFLDDFADVMQVFDGEEGLYEAESGVYDLILLDLMLPEKNGFQVLKELREKGITTPVLIMTA
KEGLDDKGHGFELGADDYLTKPFYLEELKMRIQALLKRSGKLTDHTIVYGNISVDTKINRVTVDGKEVEFLGKEFELLMY
FLQNQNVILPKTQIFDRLWGFDSDTTLSVVEVYVSKIRKKLKGTSFADHLQTLRSVGYILKDA
MIKLLLVEDDLSLSNSVFDFLDDFADVMQVFDGEEGLYEAESGVYDLILLDLMLPEKNGFQVLKELREKGITTPVLIMTA
KEGLDDKGHGFELGADDYLTKPFYLEELKMRIQALLKRSGKLTDHTIVYGNISVDTKINRVTVDGKEVEFLGKEFELLMY
FLQNQNVILPKTQIFDRLWGFDSDTTLSVVEVYVSKIRKKLKGTSFADHLQTLRSVGYILKDA
Nucleotide
Download Length: 672 bp
>NTDB_id=1022589 AB1395_RS05055 WP_218654371.1 984955..985626(-) (ciaR) [Streptococcus pluranimalium strain SS-15]
ATGATAAAATTACTCTTGGTTGAAGATGATTTGAGTTTGTCCAATTCTGTATTTGATTTTCTGGATGATTTTGCAGATGT
GATGCAGGTCTTTGATGGGGAAGAAGGATTGTATGAAGCTGAATCTGGTGTTTATGATCTTATTTTACTAGATCTTATGC
TTCCAGAAAAAAATGGTTTTCAAGTGCTAAAAGAGCTTCGAGAAAAAGGGATAACAACACCTGTTTTAATTATGACAGCA
AAGGAAGGGTTGGATGATAAGGGACATGGTTTTGAGTTAGGAGCAGATGATTATTTAACTAAGCCATTTTATCTAGAAGA
ATTAAAAATGAGAATTCAAGCCTTACTTAAACGTTCTGGAAAGTTGACCGATCATACCATCGTATACGGTAATATTAGCG
TTGACACGAAAATTAATCGTGTTACAGTAGATGGCAAAGAAGTAGAATTTTTAGGCAAAGAATTTGAATTGTTAATGTAC
TTTCTACAAAACCAAAATGTTATTTTACCTAAAACACAGATTTTTGATCGTTTATGGGGATTTGATAGCGATACAACGCT
TTCGGTTGTTGAAGTTTATGTGTCAAAAATCCGTAAAAAACTTAAAGGAACGAGTTTTGCAGATCATTTACAGACTTTAA
GAAGTGTTGGTTATATTTTAAAAGATGCATAA
ATGATAAAATTACTCTTGGTTGAAGATGATTTGAGTTTGTCCAATTCTGTATTTGATTTTCTGGATGATTTTGCAGATGT
GATGCAGGTCTTTGATGGGGAAGAAGGATTGTATGAAGCTGAATCTGGTGTTTATGATCTTATTTTACTAGATCTTATGC
TTCCAGAAAAAAATGGTTTTCAAGTGCTAAAAGAGCTTCGAGAAAAAGGGATAACAACACCTGTTTTAATTATGACAGCA
AAGGAAGGGTTGGATGATAAGGGACATGGTTTTGAGTTAGGAGCAGATGATTATTTAACTAAGCCATTTTATCTAGAAGA
ATTAAAAATGAGAATTCAAGCCTTACTTAAACGTTCTGGAAAGTTGACCGATCATACCATCGTATACGGTAATATTAGCG
TTGACACGAAAATTAATCGTGTTACAGTAGATGGCAAAGAAGTAGAATTTTTAGGCAAAGAATTTGAATTGTTAATGTAC
TTTCTACAAAACCAAAATGTTATTTTACCTAAAACACAGATTTTTGATCGTTTATGGGGATTTGATAGCGATACAACGCT
TTCGGTTGTTGAAGTTTATGTGTCAAAAATCCGTAAAAAACTTAAAGGAACGAGTTTTGCAGATCATTTACAGACTTTAA
GAAGTGTTGGTTATATTTTAAAAGATGCATAA
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| ciaR | Streptococcus mutans UA159 |
87.444 |
100 |
0.874 |
| ciaR | Streptococcus pneumoniae Rx1 |
86.547 |
100 |
0.865 |
| ciaR | Streptococcus pneumoniae D39 |
86.547 |
100 |
0.865 |
| ciaR | Streptococcus pneumoniae R6 |
86.547 |
100 |
0.865 |
| ciaR | Streptococcus pneumoniae TIGR4 |
86.547 |
100 |
0.865 |
| covR | Lactococcus lactis subsp. lactis strain DGCC12653 |
35.841 |
100 |
0.363 |