Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEC/celB   Type   Machinery gene
Locus tag   ABZ559_RS02325 Genome accession   NZ_CP160400
Coordinates   460893..462566 (+) Length   557 a.a.
NCBI ID   WP_367007156.1    Uniprot ID   -
Organism   Streptococcus sp. ZY19097     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Genomic island 448364..472414 460893..462566 within 0
IScluster/Tn 463045..477532 460893..462566 flank 479


Gene organization within MGE regions


Location: 448364..477532
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ABZ559_RS02250 (ABZ559_02250) rhuM 448364..448651 (+) 288 WP_367007148.1 RhuM family protein -
  ABZ559_RS02255 (ABZ559_02255) - 448814..449287 (+) 474 WP_018375294.1 MarR family transcriptional regulator -
  ABZ559_RS02260 (ABZ559_02260) - 449322..449858 (+) 537 WP_367007149.1 flavodoxin domain-containing protein -
  ABZ559_RS02265 (ABZ559_02265) - 450116..451678 (+) 1563 WP_245538833.1 recombinase family protein -
  ABZ559_RS02270 (ABZ559_02270) - 451675..451938 (+) 264 WP_367007150.1 DUF4368 domain-containing protein -
  ABZ559_RS02275 (ABZ559_02275) sstT 452039..453253 (+) 1215 WP_026217104.1 serine/threonine transporter SstT -
  ABZ559_RS02280 (ABZ559_02280) - 453410..454252 (+) 843 WP_273404959.1 S-adenosyl-l-methionine hydroxide adenosyltransferase family protein -
  ABZ559_RS02285 (ABZ559_02285) - 454435..454983 (+) 549 WP_273404957.1 ECF-type riboflavin transporter substrate-binding protein -
  ABZ559_RS02290 (ABZ559_02290) - 455142..456818 (+) 1677 WP_367007151.1 ABC transporter ATP-binding protein -
  ABZ559_RS02295 (ABZ559_02295) - 456811..457641 (+) 831 WP_367007152.1 energy-coupling factor transporter transmembrane component T -
  ABZ559_RS02300 (ABZ559_02300) - 457674..457964 (-) 291 WP_051071837.1 GIY-YIG nuclease family protein -
  ABZ559_RS02305 (ABZ559_02305) - 457966..458727 (-) 762 WP_367007153.1 tRNA1(Val) (adenine(37)-N6)-methyltransferase -
  ABZ559_RS02310 (ABZ559_02310) - 458762..459286 (-) 525 WP_367007154.1 HXXEE domain-containing protein -
  ABZ559_RS02315 (ABZ559_02315) - 459410..460150 (+) 741 WP_277291104.1 1-acyl-sn-glycerol-3-phosphate acyltransferase -
  ABZ559_RS02320 (ABZ559_02320) - 460205..460900 (+) 696 WP_367007155.1 helix-hairpin-helix domain-containing protein -
  ABZ559_RS02325 (ABZ559_02325) comEC/celB 460893..462566 (+) 1674 WP_367007156.1 ComEC/Rec2 family competence protein Machinery gene
  ABZ559_RS02330 (ABZ559_02330) - 462837..462920 (+) 84 WP_013641314.1 23S rRNA methyltransferase attenuation leader peptide -
  ABZ559_RS02335 (ABZ559_02335) erm(B) 463045..463782 (+) 738 WP_002321849.1 23S rRNA (adenine(2058)-N(6))-methyltransferase Erm(B) -
  ABZ559_RS02340 (ABZ559_02340) - 463952..464173 (+) 222 Protein_456 topoisomerase DNA-binding C4 zinc finger domain-containing protein -
  ABZ559_RS02345 (ABZ559_02345) - 464200..464838 (+) 639 WP_024411463.1 Vat family streptogramin A O-acetyltransferase -
  ABZ559_RS02350 (ABZ559_02350) - 465037..465531 (+) 495 WP_024411462.1 nucleotidyltransferase family protein -
  ABZ559_RS02355 (ABZ559_02355) - 465897..466775 (+) 879 WP_024411461.1 AraC family transcriptional regulator -
  ABZ559_RS02360 (ABZ559_02360) - 467332..467469 (+) 138 WP_158531099.1 hypothetical protein -
  ABZ559_RS02365 (ABZ559_02365) - 467613..467858 (+) 246 WP_000567889.1 single-stranded DNA-binding protein -
  ABZ559_RS02370 (ABZ559_02370) - 467961..468830 (+) 870 WP_367007157.1 nucleotidyltransferase domain-containing protein -
  ABZ559_RS02375 (ABZ559_02375) - 468811..469545 (+) 735 WP_000662263.1 bifunctional 2-polyprenyl-6-hydroxyphenol methylase/3-demethylubiquinol 3-O-methyltransferase UbiG -
  ABZ559_RS02380 (ABZ559_02380) - 469578..470441 (+) 864 WP_002294505.1 aminoglycoside nucleotidyltransferase ANT(6)-Ia -
  ABZ559_RS02385 (ABZ559_02385) - 470485..470607 (+) 123 Protein_465 adenine phosphoribosyltransferase -
  ABZ559_RS02390 (ABZ559_02390) - 470609..470974 (+) 366 WP_002303448.1 GNAT family N-acetyltransferase -
  ABZ559_RS02395 (ABZ559_02395) - 470975..472414 (+) 1440 WP_001028141.1 bifunctional aminoglycoside N-acetyltransferase AAC(6')-Ie/aminoglycoside O-phosphotransferase APH(2'')-Ia -
  ABZ559_RS02400 (ABZ559_02400) - 472544..473008 (-) 465 Protein_468 transposase -
  ABZ559_RS02405 (ABZ559_02405) - 473083..473763 (+) 681 WP_029180466.1 IS6-like element IS1216 family transposase -
  ABZ559_RS02410 (ABZ559_02410) - 473797..474099 (-) 303 WP_029743928.1 helix-turn-helix transcriptional regulator -
  ABZ559_RS02415 (ABZ559_02415) - 474229..476115 (+) 1887 WP_024376919.1 XRE family transcriptional regulator -
  ABZ559_RS02420 (ABZ559_02420) - 476330..477532 (-) 1203 WP_367005835.1 IS110 family transposase -

Sequence

Protein


Download         Length: 557 a.a.        Molecular weight: 63868.05 Da        Isoelectric Point: 9.1205

>NTDB_id=1020917 ABZ559_RS02325 WP_367007156.1 460893..462566(+) (comEC/celB) [Streptococcus sp. ZY19097]
MTNYLPIKPIHLAFLLVLLYFLIFSWTVAGLILFIFALINLYRHYGSKKFFQTFGCLLVFGLYFVTLHFKQEQDYAAAPA
SLTQIELVPDTISINGDLLSFEGKSNGRTYQAFYQFKSQEEQSFFQKLDKTIILTVQATTEEATPRRNFKGFDYRSYLKR
KGIYRIVKIETITNMQQAIRLSLTGYLHDWRRKAIVHIQQSFPSPMQHYMTGLLFGYLDKSFEEMGNLYSSLGIIHLFAL
SGMQVGFFLGIFRFLFLRMGWRKDYVDWLQIPFSICYAGLTGFSVSVIRSLIQASLTNLEIKRLDNLALTLMIMFFFLPH
YLLTTGGVLSFSYAFILSLIDFDGLSEYRKKLAETTAITFGILPVLIFYFATFQPASIVLTAVFSLVFDVFMLPVLSVIF
LLSPLVKISFVNGIFEGLERVVTWVERYFNHPLVFGQPDLTVFLSMLIALGFLYDVLRRKKLVLQLCLLLPLLFFISKNP
PCNEVTVVDIGQGDSIFLRDVTGKTVLIDVGGKVSFSSQESWQERQSDSNAERTLIPYLKSRGVDKIDQLVLTHTEV

Nucleotide


Download         Length: 1674 bp        

>NTDB_id=1020917 ABZ559_RS02325 WP_367007156.1 460893..462566(+) (comEC/celB) [Streptococcus sp. ZY19097]
TTGACTAATTACTTACCTATTAAGCCAATTCATTTGGCTTTTTTGCTAGTCTTACTTTATTTTCTTATTTTTTCATGGAC
AGTAGCGGGGCTAATTTTATTTATCTTTGCTCTCATTAATTTGTATCGACATTATGGGTCTAAGAAATTCTTTCAAACAT
TTGGTTGTTTGTTGGTTTTTGGTTTATATTTTGTGACACTGCACTTTAAACAAGAACAGGACTATGCAGCAGCGCCAGCC
AGTCTGACTCAGATTGAACTGGTGCCTGATACCATTTCAATTAATGGTGATTTGTTATCTTTTGAGGGTAAATCTAATGG
TAGGACCTATCAAGCTTTTTACCAATTCAAGTCGCAAGAGGAGCAAAGCTTTTTCCAAAAATTGGATAAAACTATAATTT
TGACAGTTCAAGCGACAACCGAGGAAGCCACACCTCGACGTAACTTCAAGGGATTTGATTATCGGAGTTATCTCAAACGC
AAAGGGATTTATCGCATAGTTAAAATCGAGACTATTACAAACATGCAACAAGCAATTAGACTATCTCTAACTGGCTATTT
GCATGATTGGCGTAGAAAAGCCATTGTTCACATTCAGCAGAGTTTTCCTTCCCCTATGCAGCATTACATGACAGGCCTGC
TTTTTGGATATTTGGATAAGTCTTTTGAAGAGATGGGCAATCTTTACTCTAGTCTTGGGATTATCCATCTTTTTGCCCTT
TCTGGTATGCAGGTAGGTTTTTTTCTAGGTATTTTTCGCTTCCTTTTTTTGAGAATGGGCTGGCGCAAAGATTATGTAGA
TTGGCTACAAATTCCTTTTTCCATTTGTTATGCAGGGTTGACAGGTTTCTCTGTATCAGTTATCCGTAGTCTCATTCAAG
CTAGTTTGACAAATTTAGAAATCAAACGTTTGGATAATCTTGCGCTGACGCTGATGATTATGTTCTTTTTCCTACCGCAT
TACCTTTTGACAACAGGTGGAGTGCTAAGTTTTTCCTATGCGTTTATCTTATCTCTGATTGATTTTGATGGGCTTAGTGA
GTATCGTAAGAAACTTGCGGAGACTACTGCCATTACTTTTGGAATCTTACCTGTTTTAATTTTTTATTTTGCAACTTTTC
AGCCCGCATCAATTGTGTTGACAGCTGTATTTTCTCTAGTCTTTGATGTTTTTATGTTGCCCGTCTTATCGGTGATATTT
CTATTATCACCATTAGTAAAAATCAGTTTTGTTAATGGTATTTTTGAAGGATTGGAAAGAGTAGTGACATGGGTAGAACG
ATATTTCAATCACCCGTTAGTCTTTGGACAACCTGATTTAACTGTATTTTTATCCATGTTGATTGCCTTAGGATTTCTTT
ATGATGTTCTAAGGAGAAAAAAGTTGGTGCTACAACTTTGCTTACTTTTGCCTCTGCTATTTTTCATAAGCAAGAACCCA
CCGTGCAACGAGGTAACGGTGGTTGATATTGGTCAAGGCGATAGTATTTTTCTGCGGGACGTCACTGGAAAGACAGTGCT
TATTGATGTGGGCGGGAAGGTCAGTTTTTCATCTCAAGAGAGCTGGCAGGAGCGACAATCAGATAGCAATGCAGAGCGTA
CGTTAATCCCTTATCTCAAAAGTAGAGGTGTTGATAAAATTGATCAGTTAGTGCTGACTCATACCGAAGTGTGA

Domains

Predicted by InterproScan.

Competence protein (Competence)

(213-459)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEC/celB Streptococcus mitis SK321

49.192

100

0.492
  comEC/celB Streptococcus pneumoniae TIGR4

48.905

98.384

0.481
  comEC/celB Streptococcus mitis NCTC 12261

48.634

98.564

0.479
  comEC/celB Streptococcus pneumoniae D39

48.27

98.564

0.476
  comEC/celB Streptococcus pneumoniae Rx1

48.27

98.564

0.476
  comEC/celB Streptococcus pneumoniae R6

48.27

98.564

0.476
  comEC Lactococcus lactis subsp. cremoris KW2

44.384

99.102

0.44

Multiple sequence alignment