Detailed information NTG1018615

Bioinformatically predicted

Overview

• Name: comGF
• Type: Machinery gene
• Locus tag: DQL34_RS10315
• Genome accession: NZ_LS483339
• Coordinates: 1946476..1946913 (-)
• Length: 145 a.a.
• NCBI ID: WP_084825661.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus strain NCTC12958
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1941476..1951913

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQL34_RS10280 (NCTC12958_02173)	-	1941535..1942197 (-)	663	WP_096811680.1	CPBP family intramembrane glutamic endopeptidase	-
DQL34_RS10285 (NCTC12958_02174)	-	1942300..1942743 (-)	444	WP_011681680.1	hypothetical protein	-
DQL34_RS12285 (NCTC12958_02175)	-	1942817..1943242 (-)	426	WP_111679733.1	CPBP family intramembrane glutamic endopeptidase	-
DQL34_RS10295 (NCTC12958_02176)	-	1943485..1943682 (-)	198	WP_014727723.1	helix-turn-helix transcriptional regulator	-
DQL34_RS10300 (NCTC12958_02177)	-	1943931..1945124 (-)	1194	WP_084826168.1	acetate kinase	-
DQL34_RS10305 (NCTC12958_02178)	comGH	1945180..1946136 (-)	957	WP_023909974.1	class I SAM-dependent methyltransferase	Machinery gene
DQL34_RS10310 (NCTC12958_02179)	comGG	1946181..1946498 (-)	318	WP_023909975.1	competence type IV pilus minor pilin ComGG	Machinery gene
DQL34_RS10315 (NCTC12958_02180)	comGF	1946476..1946913 (-)	438	WP_084825661.1	competence type IV pilus minor pilin ComGF	Machinery gene
DQL34_RS10320 (NCTC12958_02181)	comGE	1946897..1947190 (-)	294	WP_100262274.1	competence type IV pilus minor pilin ComGE	Machinery gene
DQL34_RS10325 (NCTC12958_02182)	comGD	1947162..1947590 (-)	429	WP_171815055.1	competence type IV pilus minor pilin ComGD	Machinery gene
DQL34_RS10330 (NCTC12958_02183)	comGC	1947550..1947876 (-)	327	WP_023909980.1	competence type IV pilus major pilin ComGC	Machinery gene
DQL34_RS10335 (NCTC12958_02184)	comGB	1947873..1948973 (-)	1101	WP_133264040.1	competence type IV pilus assembly protein ComGB	Machinery gene
DQL34_RS10340 (NCTC12958_02185)	comGA	1948855..1949796 (-)	942	WP_014622005.1	competence type IV pilus ATPase ComGA	Machinery gene
DQL34_RS10345 (NCTC12958_02186)	-	1949877..1950239 (-)	363	WP_111679734.1	DUF1033 family protein	-

Sequence

Protein

• Length: 145 a.a.
• Molecular weight: 16345.87 Da
• Isoelectric Point: 9.3928

>NTDB_id=1018615 DQL34_RS10315 WP_084825661.1 1946476..1946913(-) (comGF) [Streptococcus thermophilus strain NCTC12958]
MYLSSKLRAFTLLECLVALLVIAGSVQVYQGLTTVLVSNVKRVRQQENQDWLLFVQQMEAELEGCQLVKVEGNKLYVKQD
NQDLAFGLSSASDFRKTNADGRGYQPMLFDVKSSKVSQKNQIVTIQVTLKNGLQRSFIYAFEKTG

Nucleotide

• Length: 438 bp

>NTDB_id=1018615 DQL34_RS10315 WP_084825661.1 1946476..1946913(-) (comGF) [Streptococcus thermophilus strain NCTC12958]
ATGTATCTAAGCAGTAAGCTGCGTGCCTTTACCCTCTTGGAATGTCTAGTGGCCTTGTTAGTCATTGCTGGCTCAGTTCA
AGTTTATCAAGGGTTAACCACTGTACTTGTGAGTAATGTTAAGCGGGTAAGACAACAAGAAAACCAAGACTGGCTTCTAT
TTGTTCAACAAATGGAGGCAGAATTAGAAGGATGTCAGTTGGTCAAGGTAGAGGGGAACAAACTCTATGTCAAGCAGGAT
AATCAAGACTTGGCTTTTGGTCTTTCAAGTGCCTCTGATTTTCGAAAAACAAATGCTGATGGTCGAGGCTATCAACCAAT
GCTTTTCGATGTCAAATCTAGTAAGGTAAGTCAAAAGAACCAGATAGTTACCATCCAAGTGACTCTTAAAAATGGACTAC
AAAGGAGTTTTATTTATGCTTTTGAAAAAACAGGTTAG

Domains

Predicted by InterProScan.

• Putative Competence protein ComGF (ComGF) (40-134)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGF	Streptococcus mutans UA140	58.156	97.241	0.566
comGF	Streptococcus mutans UA159	57.447	97.241	0.559
comGF/cglF	Streptococcus pneumoniae D39	50.714	96.552	0.49
comGF/cglF	Streptococcus pneumoniae Rx1	50.714	96.552	0.49
comGF/cglF	Streptococcus pneumoniae R6	50.714	96.552	0.49
comGF/cglF	Streptococcus pneumoniae TIGR4	50.714	96.552	0.49
comGF/cglF	Streptococcus mitis NCTC 12261	48.936	97.241	0.476
comGF/cglF	Streptococcus mitis SK321	48.227	97.241	0.469
comGF	Lactococcus lactis subsp. cremoris KW2	46.763	95.862	0.448