Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGD   Type   Machinery gene
Locus tag   DQL30_RS00780 Genome accession   NZ_LS483333
Coordinates   117336..117764 (+) Length   142 a.a.
NCBI ID   WP_002986548.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain NCTC12048     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 112336..122764
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQL30_RS00760 (NCTC12048_00154) - 114679..115044 (+) 366 WP_002986560.1 DUF1033 family protein -
  DQL30_RS00765 (NCTC12048_00155) comGA 115137..116075 (+) 939 WP_111713563.1 competence type IV pilus ATPase ComGA Machinery gene
  DQL30_RS00770 (NCTC12048_00156) comGB 116011..117045 (+) 1035 WP_227868709.1 competence type IV pilus assembly protein ComGB Machinery gene
  DQL30_RS00775 (NCTC12048_00157) comGC 117047..117361 (+) 315 WP_111713564.1 competence type IV pilus major pilin ComGC Machinery gene
  DQL30_RS00780 (NCTC12048_00158) comGD 117336..117764 (+) 429 WP_002986548.1 competence type IV pilus minor pilin ComGD Machinery gene
  DQL30_RS00785 (NCTC12048_00159) comGE 117721..118005 (+) 285 WP_011284422.1 competence type IV pilus minor pilin ComGE Machinery gene
  DQL30_RS00790 (NCTC12048_00160) comGF 117998..118432 (+) 435 WP_002992738.1 competence type IV pilus minor pilin ComGF Machinery gene
  DQL30_RS00795 (NCTC12048_00161) comGG 118416..118742 (+) 327 WP_010921801.1 competence type IV pilus minor pilin ComGG -
  DQL30_RS00800 (NCTC12048_00162) comGH 118840..119793 (+) 954 WP_002987790.1 class I SAM-dependent methyltransferase Machinery gene
  DQL30_RS00805 (NCTC12048_00163) - 119852..121048 (+) 1197 WP_010921803.1 acetate kinase -
  DQL30_RS00810 - 121235..121543 (+) 309 Protein_112 hypothetical protein -
  DQL30_RS00815 (NCTC12048_00164) proC 121626..122396 (-) 771 WP_038433852.1 pyrroline-5-carboxylate reductase -

Sequence

Protein


Download         Length: 142 a.a.        Molecular weight: 16310.04 Da        Isoelectric Point: 10.3481

>NTDB_id=1017943 DQL30_RS00780 WP_002986548.1 117336..117764(+) (comGD) [Streptococcus pyogenes strain NCTC12048]
MKKPVLAIKAFTLLETLLSLSVMSFIILGLSVPVTKSYQKVEEHLFFSHFEHLYRHQQKLAILQQKQRVLDISSTKIVTE
GNSLTVPKSITVNHPYRLVIDQMGGNHSLAKIIFDMTDRRFKYQFYLGSGNYQKTSQSLHSP

Nucleotide


Download         Length: 429 bp        

>NTDB_id=1017943 DQL30_RS00780 WP_002986548.1 117336..117764(+) (comGD) [Streptococcus pyogenes strain NCTC12048]
ATGAAAAAGCCCGTCTTAGCAATTAAAGCTTTTACTTTGCTTGAAACTTTACTAAGTTTGTCAGTGATGAGTTTCATTAT
ATTGGGATTGTCTGTACCAGTGACAAAAAGCTATCAAAAAGTAGAAGAGCATCTGTTTTTTAGCCATTTTGAACATTTGT
ATCGACATCAGCAAAAGTTAGCCATATTACAGCAAAAACAGCGCGTCTTGGATATTTCTTCAACAAAAATTGTTACAGAA
GGTAATAGCCTAACAGTTCCTAAATCAATAACAGTGAATCATCCTTATCGGTTAGTTATTGATCAGATGGGAGGCAACCA
TTCCTTAGCCAAAATTATTTTTGACATGACTGATCGACGCTTTAAATACCAATTTTATCTAGGGAGTGGGAATTATCAAA
AAACAAGTCAAAGCTTACATAGCCCTTGA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGD Streptococcus mutans UA159

45.736

90.845

0.415
  comGD Streptococcus mutans UA140

45.736

90.845

0.415
  comGD/cglD Streptococcus mitis NCTC 12261

40.441

95.775

0.387
  comGD Streptococcus gordonii str. Challis substr. CH1

40.458

92.254

0.373
  comGD/cglD Streptococcus mitis SK321

39.695

92.254

0.366
  comGD/cglD Streptococcus pneumoniae Rx1

39.695

92.254

0.366
  comGD/cglD Streptococcus pneumoniae D39

39.695

92.254

0.366
  comGD/cglD Streptococcus pneumoniae R6

39.695

92.254

0.366

Multiple sequence alignment