Detailed information    

insolico Bioinformatically predicted

Overview

Name   coiA   Type   Machinery gene
Locus tag   DQL25_RS04145 Genome accession   NZ_LS483330
Coordinates   768410..769372 (+) Length   320 a.a.
NCBI ID   WP_111703226.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain NCTC8328     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 763410..774372
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQL25_RS04125 (NCTC8328_00821) - 764119..765339 (-) 1221 WP_111703223.1 DUF3114 domain-containing protein -
  DQL25_RS04130 (NCTC8328_00822) queA 765344..766372 (-) 1029 WP_111703224.1 tRNA preQ1(34) S-adenosylmethionine ribosyltransferase-isomerase QueA -
  DQL25_RS04135 (NCTC8328_00823) nagB 766574..767278 (+) 705 WP_111703225.1 glucosamine-6-phosphate deaminase -
  DQL25_RS04140 (NCTC8328_00824) - 767397..768113 (+) 717 WP_002989197.1 pseudouridine synthase -
  DQL25_RS04145 (NCTC8328_00825) coiA 768410..769372 (+) 963 WP_111703226.1 competence protein CoiA Machinery gene
  DQL25_RS04150 (NCTC8328_00826) pepF 769385..771190 (+) 1806 WP_111703227.1 oligoendopeptidase F Regulator
  DQL25_RS04155 (NCTC8328_00827) - 771566..772762 (+) 1197 WP_002995765.1 OFA family MFS transporter -
  DQL25_RS04160 (NCTC8328_00828) - 772828..773535 (+) 708 WP_002989211.1 O-methyltransferase -

Sequence

Protein


Download         Length: 320 a.a.        Molecular weight: 37811.24 Da        Isoelectric Point: 10.2848

>NTDB_id=1017689 DQL25_RS04145 WP_111703226.1 768410..769372(+) (coiA) [Streptococcus pyogenes strain NCTC8328]
MTKILTALDGKNQLISLVTQPISTKPPFRCPACKSPVRLRQGTIRRPHFAHVQLAHCQFQAENESEEHLTLKAKLYTSLV
RTEAVCIEKYLPELQQIADLWVNDKLALEIQCSPLTVERLKKRTKAYQEKGYLVRWLLGRKLWLNTHLTALQKQFLYFSS
SLGFHLWELDAAANLLRLKYLIHEDLFGKVSYLTKTISLDHNIMEMFRLPYQQEILYSYQKKMTVNLSKRIQRALLARHS
KWLRRQEKAYLSGYNLLMLTTDAFYPQWRPVQSSSGFCQIKGNLRPYYESFKVYYKKEKDKKVQTLFSPKYYVKMDSNRK

Nucleotide


Download         Length: 963 bp        

>NTDB_id=1017689 DQL25_RS04145 WP_111703226.1 768410..769372(+) (coiA) [Streptococcus pyogenes strain NCTC8328]
GTGACAAAAATATTAACCGCTTTAGATGGTAAGAATCAGCTTATTTCGCTAGTAACTCAGCCTATTTCAACGAAACCGCC
TTTTCGTTGCCCAGCTTGCAAATCTCCTGTTCGCTTGCGTCAGGGGACAATTAGACGACCTCATTTTGCCCATGTACAAC
TAGCTCATTGTCAATTCCAAGCAGAAAATGAATCTGAGGAACATTTGACGTTGAAGGCAAAACTTTACACCAGTTTAGTC
CGAACAGAAGCTGTCTGTATTGAAAAATATCTTCCTGAGCTGCAACAGATAGCAGACCTTTGGGTGAATGATAAGTTAGC
CTTAGAAATTCAGTGCAGTCCCTTGACAGTTGAGCGTCTAAAGAAACGCACCAAAGCCTATCAAGAAAAGGGGTATCTGG
TACGATGGTTACTGGGAAGAAAATTGTGGCTTAACACTCACTTAACTGCTTTGCAAAAACAGTTTCTTTACTTTTCATCT
AGTTTGGGCTTTCATTTGTGGGAGCTGGATGCAGCTGCAAATCTGCTACGTCTCAAATATTTAATCCATGAAGACTTATT
TGGTAAGGTAAGTTACCTAACCAAAACCATTTCTTTAGACCACAATATTATGGAAATGTTTCGATTACCCTATCAGCAAG
AAATCCTTTATTCTTATCAGAAAAAAATGACTGTGAACCTATCTAAAAGAATACAAAGAGCTCTTTTAGCTAGACACTCG
AAATGGCTACGACGACAAGAAAAGGCTTACTTATCAGGCTATAATTTACTTATGTTAACAACTGATGCTTTTTATCCTCA
ATGGAGACCAGTTCAATCTTCCAGCGGTTTTTGTCAAATTAAAGGAAATCTTCGCCCTTATTATGAAAGTTTTAAAGTCT
ATTATAAAAAAGAAAAGGATAAGAAGGTGCAAACGCTTTTTTCACCAAAATATTATGTTAAAATGGATAGTAATAGAAAA
TGA

Domains

Predicted by InterProScan.

Competence protein CoiA-like family (CoiA_nuc)

(19-264)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  coiA Streptococcus mitis NCTC 12261

42.258

96.875

0.409
  coiA Streptococcus pneumoniae Rx1

41.29

96.875

0.4
  coiA Streptococcus pneumoniae D39

41.29

96.875

0.4
  coiA Streptococcus pneumoniae R6

41.29

96.875

0.4
  coiA Streptococcus pneumoniae TIGR4

41.29

96.875

0.4
  coiA Lactococcus lactis subsp. cremoris KW2

39.024

100

0.4

Multiple sequence alignment