NTDB

Overview

Name	ruvA	Type	Machinery gene
Locus tag	DQL05_RS08380	Genome accession	NZ_LS483322
Coordinates	1659885..1660481 (-)	Length	198 a.a.
NCBI ID	WP_002992186.1	Uniprot ID	P0DF49
Organism	Streptococcus pyogenes strain NCTC12066
Function	homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 1654885..1665481

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQL05_RS08345 (NCTC12066_01651)	-	1654944..1655249 (-)	306	WP_002982199.1	DUF1292 domain-containing protein	-
DQL05_RS08350 (NCTC12066_01652)	ruvX	1655261..1655680 (-)	420	WP_002982196.1	Holliday junction resolvase RuvX	-
DQL05_RS08355 (NCTC12066_01653)	-	1655677..1655946 (-)	270	WP_002982194.1	IreB family regulatory phosphoprotein	-
DQL05_RS08360 (NCTC12066_01654)	spx	1656061..1656459 (-)	399	WP_002982188.1	transcriptional regulator Spx	-
DQL05_RS08365 (NCTC12066_01655)	recA	1656750..1657886 (-)	1137	WP_109828910.1	recombinase RecA	Machinery gene
DQL05_RS08370 (NCTC12066_01656)	cinA	1657975..1659246 (-)	1272	WP_011055089.1	competence/damage-inducible protein A	Machinery gene
DQL05_RS08375 (NCTC12066_01657)	-	1659315..1659875 (-)	561	WP_002992183.1	DNA-3-methyladenine glycosylase I	-
DQL05_RS08380 (NCTC12066_01658)	ruvA	1659885..1660481 (-)	597	WP_002992186.1	Holliday junction branch migration protein RuvA	Machinery gene
DQL05_RS08385 (NCTC12066_01659)	-	1660483..1661703 (-)	1221	WP_002992187.1	MDR family MFS transporter	-
DQL05_RS08390 (NCTC12066_01660)	hexB	1661714..1663696 (-)	1983	WP_002992189.1	DNA mismatch repair endonuclease MutL	Machinery gene
DQL05_RS08395 (NCTC12066_01661)	-	1663791..1664942 (-)	1152	WP_172450205.1	tyrosine-type recombinase/integrase	-

Sequence

Protein

Download Length: 198 a.a. Molecular weight: 21879.26 Da Isoelectric Point: 6.8838

                                >NTDB_id=1017161 DQL05_RS08380 WP_002992186.1 1659885..1660481(-) (ruvA) [Streptococcus pyogenes strain NCTC12066]

MYDYIKGQLTKITAKYIVVEANGLGYMINVANPYSFTDSVNQLVTIYLHQVIREDAHLLFGFHTEDEKDVFLKLISVSGI

GPTTALAIVAVDDNEGLVNAIDNSDIKYLMKFPKIGKKTAQQMVLDLAGKFVEAPQETGHTKARSNKAGNTQLDEAIEAL

LALGYKAKELKKIRAFFEGTSETAEQYIKSALKLLMKG

Nucleotide

Download Length: 597 bp

                                >NTDB_id=1017161 DQL05_RS08380 WP_002992186.1 1659885..1660481(-) (ruvA) [Streptococcus pyogenes strain NCTC12066]

ATGTACGACTATATTAAAGGTCAATTGACCAAAATTACGGCAAAATACATTGTCGTTGAAGCTAATGGATTGGGCTACAT

GATTAATGTTGCCAATCCTTATAGCTTTACAGATAGTGTCAACCAATTGGTAACCATTTATCTGCATCAAGTGATTCGTG

AGGATGCTCACCTGTTGTTTGGTTTTCACACGGAAGATGAAAAAGATGTTTTTCTGAAATTAATTTCTGTATCAGGTATT

GGTCCGACAACAGCTCTTGCTATTGTGGCAGTTGATGATAATGAGGGACTTGTGAATGCCATTGATAACAGTGACATTAA

GTACCTAATGAAATTTCCTAAAATTGGTAAAAAAACAGCGCAGCAAATGGTTCTTGACTTAGCTGGCAAATTTGTGGAGG

CTCCACAAGAGACTGGTCATACCAAAGCGCGCAGCAATAAAGCAGGCAATACTCAACTGGACGAAGCGATTGAAGCCCTC

CTTGCCCTCGGTTATAAAGCAAAAGAGCTGAAAAAAATTCGTGCCTTCTTTGAGGGGACCTCTGAGACGGCAGAGCAATA

CATCAAATCAGCATTGAAACTGTTAATGAAAGGGTAG

Domains

Predicted by InterProScan.

RuvA N terminal domain (RuvA_N)

(1-61)

Helix-hairpin-helix domain (HHH_5)

(71-127)

RuvA, C-terminal domain (RuvA_C)

(152-196)

Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.

3D structure

Source	ID	Structure
AlphaFold DB	P0DF49

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.

Visualization of predicted probability:

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	H_a-value
ruvA	Streptococcus pneumoniae TIGR4	65.99	99.495	0.657
ruvA	Streptococcus pneumoniae R6	65.99	99.495	0.657
ruvA	Streptococcus pneumoniae D39	65.99	99.495	0.657
ruvA	Bacillus subtilis subsp. subtilis str. 168	40.887	100	0.419

Detailed information NTG1017161