Detailed information NTG1016930

Bioinformatically predicted

Overview

• Name: comEC/celB
• Type: Machinery gene
• Locus tag: DQL31_RS06270
• Genome accession: NZ_LS483320
• Coordinates: 1183574..1185796 (-)
• Length: 740 a.a.
• NCBI ID: WP_111677344.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain NCTC5164
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1178574..1190796

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQL31_RS06240 (NCTC5164_01253)	-	1179202..1180422 (+)	1221	WP_011528764.1	DUF3114 domain-containing protein	-
DQL31_RS06245 (NCTC5164_01254)	-	1180536..1181126 (-)	591	WP_011528765.1	serine hydrolase	-
DQL31_RS06250 (NCTC5164_01255)	-	1181123..1181371 (-)	249	WP_111677342.1	serine hydrolase	-
DQL31_RS06255 (NCTC5164_01256)	-	1181427..1181573 (-)	147	WP_011017947.1	hypothetical protein	-
DQL31_RS06260 (NCTC5164_01257)	sodA	1181740..1182345 (-)	606	WP_002983977.1	superoxide dismutase SodA	-
DQL31_RS06265 (NCTC5164_01258)	holA	1182442..1183482 (-)	1041	WP_111677343.1	DNA polymerase III subunit delta	-
DQL31_RS06270 (NCTC5164_01259)	comEC/celB	1183574..1185796 (-)	2223	WP_111677344.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
DQL31_RS06275 (NCTC5164_01260)	-	1185777..1186439 (-)	663	WP_002983967.1	ComEA family DNA-binding protein	-
DQL31_RS06280 (NCTC5164_01261)	-	1186639..1187379 (-)	741	WP_172448859.1	lysophospholipid acyltransferase family protein	-
DQL31_RS06285 (NCTC5164_01262)	-	1187546..1188679 (-)	1134	WP_111677044.1	ISAs1-like element IS1548 family transposase	-
DQL31_RS06290 (NCTC5164_01263)	-	1188823..1189599 (+)	777	WP_111677345.1	tRNA1(Val) (adenine(37)-N6)-methyltransferase	-
DQL31_RS06295 (NCTC5164_01264)	-	1189589..1189867 (+)	279	WP_011017953.1	GIY-YIG nuclease family protein	-

Sequence

Protein

• Length: 740 a.a.
• Molecular weight: 84654.56 Da
• Isoelectric Point: 9.7536

>NTDB_id=1016930 DQL31_RS06270 WP_111677344.1 1183574..1185796(-) (comEC/celB) [Streptococcus pyogenes strain NCTC5164]
MTFSWTKLMPLSKIQFAFLILVLFYQIHSPSWLTFLLSLSLICLLVKRLSKKEFLGVFAILSFCALFLLYQKQQLVQKLE
IQPVQITSVALVPDSIRINGDQLAVLGRHGKHSYQLFYRLKSQAEAQLFKKEHRWLVMHAKVTLEKAEEVRNFKGFNYQT
FLAYQGIYRIGKVEQIEQLEVISPKSICDYLSSLRRRAIVHCQQHFPRPMSHYLTGLLFGYLDKSFGEMTDYYSQLGIIH
LFALSGMQVGFFLTCFRRVLLLLAVPLEWIKWIELPFACFYAALTGYSISVIRSLVQSQLRHLGIKGLDNLACTFLLVFL
WDAHFLMTVGGVLTFSYAFLLTVVTVEELSGAKRQLVQVLTISLGILPFLLFYFSSFNPMSMVLTALLSYLFDLFILPLL
CLVFCLSPLVTVSICNHLFILLEKVIQFLGNTFNSSLVFGSPTSWHLLILVISFAIFYDYRQVRQRVITCGLVIALTLLS
VKYPLTNEVTFIDIGQGDSILVREWTGKNLLIDVGGRPFFSSKEHWRRGHHVANAQKTLIPYLKSRGIHTIDQLLVIHAD
TDHMGDIEMVAKAIRIKEILTSQGSLSHPSFVRRLRRLKCHVRVLAAGDQLPIMGSVLQVLYPWQLGDGKNNDSLVLYGR
LLNRTFLFTGDLEKEGENEIIKRYPQLRVDYLKAGHHGSNTSSSAAFLDHIQPKVAFISAGKNNRYQHPHRETLARLEDR
QITYYRTDTQGAIRLTGWTS

Nucleotide

• Length: 2223 bp

>NTDB_id=1016930 DQL31_RS06270 WP_111677344.1 1183574..1185796(-) (comEC/celB) [Streptococcus pyogenes strain NCTC5164]
ATGACATTTTCTTGGACTAAGCTAATGCCCCTGTCAAAGATTCAATTTGCTTTTTTAATCTTGGTTCTCTTTTATCAAAT
CCATAGCCCTAGCTGGTTAACGTTTCTCCTTAGCCTTAGTTTGATTTGCTTACTTGTCAAGCGTTTGTCTAAAAAAGAAT
TTCTCGGTGTCTTTGCCATCCTTAGTTTCTGTGCTTTGTTTTTACTGTATCAGAAACAGCAGTTGGTTCAAAAACTGGAA
ATTCAGCCAGTACAAATAACCTCTGTAGCATTAGTTCCTGATAGTATTCGGATTAATGGTGATCAATTAGCTGTTCTTGG
ACGTCATGGGAAACATTCTTATCAGTTATTTTACCGTTTGAAAAGCCAAGCAGAAGCCCAATTGTTCAAGAAAGAGCACC
GTTGGTTAGTGATGCATGCAAAAGTGACATTGGAAAAAGCTGAGGAAGTTCGAAATTTTAAAGGCTTTAATTATCAGACT
TTTTTGGCTTATCAAGGAATTTACAGGATAGGGAAGGTAGAGCAAATAGAACAGCTTGAAGTGATTTCACCCAAGTCAAT
ATGTGACTATTTGTCCTCTTTAAGACGGCGAGCCATTGTTCATTGCCAGCAGCATTTTCCAAGACCTATGTCTCACTACC
TGACAGGCCTCCTTTTTGGTTATTTAGATAAGTCGTTTGGTGAGATGACAGATTATTATAGTCAGTTGGGTATCATTCAT
CTCTTTGCTTTATCAGGGATGCAGGTTGGCTTCTTTCTTACTTGTTTTAGAAGGGTGTTACTATTACTCGCAGTTCCTTT
GGAATGGATAAAATGGATAGAGCTTCCTTTTGCTTGCTTTTATGCCGCGTTGACAGGTTATAGTATTTCTGTTATTCGAA
GCCTCGTGCAGTCGCAGTTGCGTCATTTAGGAATAAAAGGATTAGACAATCTCGCTTGTACTTTTTTACTTGTCTTTTTA
TGGGATGCCCATTTCTTAATGACTGTTGGTGGCGTATTAACGTTTAGCTATGCTTTTTTGTTAACAGTGGTTACTGTTGA
AGAATTATCAGGAGCTAAAAGACAGTTGGTACAAGTCTTGACCATTTCCCTAGGAATATTACCATTTTTGCTCTTTTATT
TTTCCAGTTTTAACCCAATGTCAATGGTCTTAACAGCTCTCTTGTCTTATCTCTTTGACCTTTTTATTTTGCCCCTTCTT
TGTCTGGTTTTTTGTCTATCCCCTTTGGTGACTGTCTCAATATGTAACCATCTTTTTATTTTATTAGAAAAAGTCATTCA
ATTTCTCGGAAATACTTTCAATAGTTCCCTTGTTTTTGGAAGCCCGACCAGTTGGCACTTGCTTATCTTGGTGATTAGCT
TCGCTATTTTTTATGATTATCGGCAGGTGCGACAACGAGTTATCACTTGCGGTTTGGTTATAGCGTTGACGCTTTTGTCT
GTCAAATATCCTTTGACCAATGAAGTGACCTTTATCGACATTGGCCAGGGAGATAGTATTTTGGTGAGGGAGTGGACAGG
GAAAAATCTCTTAATAGATGTAGGTGGGCGCCCTTTCTTTTCTTCAAAAGAGCACTGGCGACGAGGACATCACGTAGCTA
ATGCTCAGAAAACCTTAATTCCTTACTTAAAAAGTAGAGGCATTCACACAATTGACCAACTATTAGTAATTCACGCAGAT
ACTGATCATATGGGGGATATAGAGATGGTTGCCAAAGCTATTCGGATAAAGGAGATTTTGACTAGTCAAGGCAGTTTAAG
CCATCCAAGCTTTGTTAGGCGGCTAAGGCGTTTAAAATGTCACGTTAGGGTTTTAGCAGCTGGAGACCAGTTGCCTATTA
TGGGAAGTGTCTTACAGGTACTCTACCCTTGGCAGTTAGGGGACGGGAAAAATAACGATTCTTTGGTACTTTATGGCAGG
CTCTTAAATCGAACTTTTCTTTTCACAGGTGACTTGGAAAAAGAGGGGGAAAACGAGATCATAAAACGTTATCCTCAACT
AAGAGTAGATTATTTAAAAGCAGGTCACCATGGATCAAATACCTCTTCTAGTGCAGCTTTTTTAGACCATATTCAGCCTA
AAGTGGCCTTTATTTCTGCTGGAAAAAATAACCGTTATCAGCATCCTCACAGAGAAACCTTAGCCCGTTTGGAAGACAGA
CAAATTACTTATTACCGAACGGATACGCAAGGAGCTATTCGTTTGACTGGTTGGACAAGCTGA

Domains

Predicted by InterProScan.

• Competence protein (Competence) (217-462)

• Metallo-beta-lactamase superfamily (Lactamase_B) (495-701)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC/celB	Streptococcus mitis SK321	46.081	100	0.461
comEC/celB	Streptococcus mitis NCTC 12261	45.811	100	0.458
comEC/celB	Streptococcus pneumoniae TIGR4	44.865	100	0.449
comEC/celB	Streptococcus pneumoniae Rx1	44.669	100	0.447
comEC/celB	Streptococcus pneumoniae D39	44.669	100	0.447
comEC/celB	Streptococcus pneumoniae R6	44.669	100	0.447
comEC	Lactococcus lactis subsp. cremoris KW2	40.884	97.838	0.4