Detailed information NTG1016016

Bioinformatically predicted

Overview

• Name: comEC/celB
• Type: Machinery gene
• Locus tag: DQL09_RS06275
• Genome accession: NZ_LS483307
• Coordinates: 1183836..1186058 (-)
• Length: 740 a.a.
• NCBI ID: WP_111677344.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain NCTC5163
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1178836..1191058

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQL09_RS06245 (NCTC5163_01253)	-	1179464..1180684 (+)	1221	WP_011528764.1	DUF3114 domain-containing protein	-
DQL09_RS06250 (NCTC5163_01254)	-	1180798..1181388 (-)	591	WP_011528765.1	serine hydrolase	-
DQL09_RS06255 (NCTC5163_01255)	-	1181385..1181633 (-)	249	WP_111677342.1	serine hydrolase	-
DQL09_RS06260 (NCTC5163_01256)	-	1181689..1181835 (-)	147	WP_011017947.1	hypothetical protein	-
DQL09_RS06265 (NCTC5163_01257)	sodA	1182002..1182607 (-)	606	WP_002983977.1	superoxide dismutase SodA	-
DQL09_RS06270 (NCTC5163_01258)	holA	1182704..1183744 (-)	1041	WP_111677343.1	DNA polymerase III subunit delta	-
DQL09_RS06275 (NCTC5163_01259)	comEC/celB	1183836..1186058 (-)	2223	WP_111677344.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
DQL09_RS06280 (NCTC5163_01260)	-	1186039..1186701 (-)	663	WP_002983967.1	ComEA family DNA-binding protein	-
DQL09_RS06285 (NCTC5163_01261)	-	1186901..1187641 (-)	741	WP_172448859.1	lysophospholipid acyltransferase family protein	-
DQL09_RS06290 (NCTC5163_01262)	-	1187808..1188941 (-)	1134	WP_111677044.1	ISAs1-like element IS1548 family transposase	-
DQL09_RS06295 (NCTC5163_01263)	-	1189085..1189861 (+)	777	WP_111677345.1	tRNA1(Val) (adenine(37)-N6)-methyltransferase	-
DQL09_RS06300 (NCTC5163_01264)	-	1189851..1190129 (+)	279	WP_011017953.1	GIY-YIG nuclease family protein	-

Sequence

Protein

• Length: 740 a.a.
• Molecular weight: 84654.56 Da
• Isoelectric Point: 9.7536

>NTDB_id=1016016 DQL09_RS06275 WP_111677344.1 1183836..1186058(-) (comEC/celB) [Streptococcus pyogenes strain NCTC5163]
MTFSWTKLMPLSKIQFAFLILVLFYQIHSPSWLTFLLSLSLICLLVKRLSKKEFLGVFAILSFCALFLLYQKQQLVQKLE
IQPVQITSVALVPDSIRINGDQLAVLGRHGKHSYQLFYRLKSQAEAQLFKKEHRWLVMHAKVTLEKAEEVRNFKGFNYQT
FLAYQGIYRIGKVEQIEQLEVISPKSICDYLSSLRRRAIVHCQQHFPRPMSHYLTGLLFGYLDKSFGEMTDYYSQLGIIH
LFALSGMQVGFFLTCFRRVLLLLAVPLEWIKWIELPFACFYAALTGYSISVIRSLVQSQLRHLGIKGLDNLACTFLLVFL
WDAHFLMTVGGVLTFSYAFLLTVVTVEELSGAKRQLVQVLTISLGILPFLLFYFSSFNPMSMVLTALLSYLFDLFILPLL
CLVFCLSPLVTVSICNHLFILLEKVIQFLGNTFNSSLVFGSPTSWHLLILVISFAIFYDYRQVRQRVITCGLVIALTLLS
VKYPLTNEVTFIDIGQGDSILVREWTGKNLLIDVGGRPFFSSKEHWRRGHHVANAQKTLIPYLKSRGIHTIDQLLVIHAD
TDHMGDIEMVAKAIRIKEILTSQGSLSHPSFVRRLRRLKCHVRVLAAGDQLPIMGSVLQVLYPWQLGDGKNNDSLVLYGR
LLNRTFLFTGDLEKEGENEIIKRYPQLRVDYLKAGHHGSNTSSSAAFLDHIQPKVAFISAGKNNRYQHPHRETLARLEDR
QITYYRTDTQGAIRLTGWTS

Nucleotide

• Length: 2223 bp

>NTDB_id=1016016 DQL09_RS06275 WP_111677344.1 1183836..1186058(-) (comEC/celB) [Streptococcus pyogenes strain NCTC5163]
ATGACATTTTCTTGGACTAAGCTAATGCCCCTGTCAAAGATTCAATTTGCTTTTTTAATCTTGGTTCTCTTTTATCAAAT
CCATAGCCCTAGCTGGTTAACGTTTCTCCTTAGCCTTAGTTTGATTTGCTTACTTGTCAAGCGTTTGTCTAAAAAAGAAT
TTCTCGGTGTCTTTGCCATCCTTAGTTTCTGTGCTTTGTTTTTACTGTATCAGAAACAGCAGTTGGTTCAAAAACTGGAA
ATTCAGCCAGTACAAATAACCTCTGTAGCATTAGTTCCTGATAGTATTCGGATTAATGGTGATCAATTAGCTGTTCTTGG
ACGTCATGGGAAACATTCTTATCAGTTATTTTACCGTTTGAAAAGCCAAGCAGAAGCCCAATTGTTCAAGAAAGAGCACC
GTTGGTTAGTGATGCATGCAAAAGTGACATTGGAAAAAGCTGAGGAAGTTCGAAATTTTAAAGGCTTTAATTATCAGACT
TTTTTGGCTTATCAAGGAATTTACAGGATAGGGAAGGTAGAGCAAATAGAACAGCTTGAAGTGATTTCACCCAAGTCAAT
ATGTGACTATTTGTCCTCTTTAAGACGGCGAGCCATTGTTCATTGCCAGCAGCATTTTCCAAGACCTATGTCTCACTACC
TGACAGGCCTCCTTTTTGGTTATTTAGATAAGTCGTTTGGTGAGATGACAGATTATTATAGTCAGTTGGGTATCATTCAT
CTCTTTGCTTTATCAGGGATGCAGGTTGGCTTCTTTCTTACTTGTTTTAGAAGGGTGTTACTATTACTCGCAGTTCCTTT
GGAATGGATAAAATGGATAGAGCTTCCTTTTGCTTGCTTTTATGCCGCGTTGACAGGTTATAGTATTTCTGTTATTCGAA
GCCTCGTGCAGTCGCAGTTGCGTCATTTAGGAATAAAAGGATTAGACAATCTCGCTTGTACTTTTTTACTTGTCTTTTTA
TGGGATGCCCATTTCTTAATGACTGTTGGTGGCGTATTAACGTTTAGCTATGCTTTTTTGTTAACAGTGGTTACTGTTGA
AGAATTATCAGGAGCTAAAAGACAGTTGGTACAAGTCTTGACCATTTCCCTAGGAATATTACCATTTTTGCTCTTTTATT
TTTCCAGTTTTAACCCAATGTCAATGGTCTTAACAGCTCTCTTGTCTTATCTCTTTGACCTTTTTATTTTGCCCCTTCTT
TGTCTGGTTTTTTGTCTATCCCCTTTGGTGACTGTCTCAATATGTAACCATCTTTTTATTTTATTAGAAAAAGTCATTCA
ATTTCTCGGAAATACTTTCAATAGTTCCCTTGTTTTTGGAAGCCCGACCAGTTGGCACTTGCTTATCTTGGTGATTAGCT
TCGCTATTTTTTATGATTATCGGCAGGTGCGACAACGAGTTATCACTTGCGGTTTGGTTATAGCGTTGACGCTTTTGTCT
GTCAAATATCCTTTGACCAATGAAGTGACCTTTATCGACATTGGCCAGGGAGATAGTATTTTGGTGAGGGAGTGGACAGG
GAAAAATCTCTTAATAGATGTAGGTGGGCGCCCTTTCTTTTCTTCAAAAGAGCACTGGCGACGAGGACATCACGTAGCTA
ATGCTCAGAAAACCTTAATTCCTTACTTAAAAAGTAGAGGCATTCACACAATTGACCAACTATTAGTAATTCACGCAGAT
ACTGATCATATGGGGGATATAGAGATGGTTGCCAAAGCTATTCGGATAAAGGAGATTTTGACTAGTCAAGGCAGTTTAAG
CCATCCAAGCTTTGTTAGGCGGCTAAGGCGTTTAAAATGTCACGTTAGGGTTTTAGCAGCTGGAGACCAGTTGCCTATTA
TGGGAAGTGTCTTACAGGTACTCTACCCTTGGCAGTTAGGGGACGGGAAAAATAACGATTCTTTGGTACTTTATGGCAGG
CTCTTAAATCGAACTTTTCTTTTCACAGGTGACTTGGAAAAAGAGGGGGAAAACGAGATCATAAAACGTTATCCTCAACT
AAGAGTAGATTATTTAAAAGCAGGTCACCATGGATCAAATACCTCTTCTAGTGCAGCTTTTTTAGACCATATTCAGCCTA
AAGTGGCCTTTATTTCTGCTGGAAAAAATAACCGTTATCAGCATCCTCACAGAGAAACCTTAGCCCGTTTGGAAGACAGA
CAAATTACTTATTACCGAACGGATACGCAAGGAGCTATTCGTTTGACTGGTTGGACAAGCTGA

Domains

Predicted by InterProScan.

• Competence protein (Competence) (217-462)

• Metallo-beta-lactamase superfamily (Lactamase_B) (495-701)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC/celB	Streptococcus mitis SK321	46.081	100	0.461
comEC/celB	Streptococcus mitis NCTC 12261	45.811	100	0.458
comEC/celB	Streptococcus pneumoniae TIGR4	44.865	100	0.449
comEC/celB	Streptococcus pneumoniae Rx1	44.669	100	0.447
comEC/celB	Streptococcus pneumoniae D39	44.669	100	0.447
comEC/celB	Streptococcus pneumoniae R6	44.669	100	0.447
comEC	Lactococcus lactis subsp. cremoris KW2	40.884	97.838	0.4