Detailed information    

insolico Bioinformatically predicted

Overview

Name   cclA/cilC   Type   Machinery gene
Locus tag   H1W81_RS06975 Genome accession   NZ_LR824002
Coordinates   1344192..1344839 (+) Length   215 a.a.
NCBI ID   WP_002950388.1    Uniprot ID   Q5M4Y9
Organism   Streptococcus thermophilus isolate STH_CIRM_67     
Function   processing and translocation of ComGC; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1339192..1349839
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H1W81_RS06950 (STHERMO_1568) - 1340514..1341482 (-) 969 WP_011225772.1 ROK family glucokinase -
  H1W81_RS06955 (STHERMO_1569) - 1341475..1341681 (-) 207 WP_002950395.1 YqgQ family protein -
  H1W81_RS06960 (STHERMO_1570) - 1341782..1342735 (-) 954 WP_041826943.1 IS30 family transposase -
  H1W81_RS06965 (STHERMO_1571) - 1343036..1343473 (-) 438 WP_011225769.1 Fur family transcriptional regulator -
  H1W81_RS06970 (STHERMO_1572) - 1343562..1344083 (-) 522 WP_011225768.1 Dps family protein -
  H1W81_RS06975 (STHERMO_1573) cclA/cilC 1344192..1344839 (+) 648 WP_002950388.1 prepilin peptidase Machinery gene
  H1W81_RS06980 (STHERMO_1574) - 1344879..1346258 (-) 1380 WP_011225767.1 serine hydrolase -
  H1W81_RS06985 (STHERMO_1575) sodA 1346355..1346960 (-) 606 WP_011680996.1 superoxide dismutase SodA -
  H1W81_RS06990 (STHERMO_1576) holA 1347055..1348089 (-) 1035 WP_002946639.1 DNA polymerase III subunit delta -

Sequence

Protein


Download         Length: 215 a.a.        Molecular weight: 24887.00 Da        Isoelectric Point: 8.3836

>NTDB_id=1012175 H1W81_RS06975 WP_002950388.1 1344192..1344839(+) (cclA/cilC) [Streptococcus thermophilus isolate STH_CIRM_67]
MLSILYFFLGTSLGSFIGLICDRFPEKSIIFPRSHCNQCGHPLRFFEMIPILSQLFLRFKCRLCQSSIPYRYLFLELFCG
GILLLYFYDYLDFGRTYLLFFSLCLTIFDLKNKSYPLLIWILGTLPLLCLGNHYLTFSLGISLAVLSYIKRLNIGEGDFL
YLASVSLIFPFSKILIAIELACSFGLMYFLVRKNPNETVAFVPFLFMSVLILTFM

Nucleotide


Download         Length: 648 bp        

>NTDB_id=1012175 H1W81_RS06975 WP_002950388.1 1344192..1344839(+) (cclA/cilC) [Streptococcus thermophilus isolate STH_CIRM_67]
ATGCTTAGTATTTTATATTTTTTTCTTGGTACCTCTTTAGGCTCGTTTATTGGATTGATTTGTGATCGTTTTCCTGAGAA
GTCGATTATTTTTCCTAGAAGCCATTGCAATCAGTGTGGGCATCCGTTACGTTTTTTCGAAATGATTCCGATCCTATCAC
AACTTTTCTTAAGGTTCAAATGTCGGTTATGTCAAAGCTCTATCCCATACCGTTACCTCTTCTTGGAATTGTTTTGTGGA
GGAATACTTCTTCTTTATTTCTATGACTACCTAGATTTCGGAAGAACCTATTTGCTTTTTTTCAGTCTTTGTCTAACTAT
TTTTGATTTAAAAAATAAATCATATCCCCTTCTAATTTGGATTCTTGGAACACTACCTCTCCTATGTTTGGGAAACCACT
ACCTCACTTTTAGCTTAGGAATAAGTTTAGCCGTTCTGTCATATATCAAACGTTTAAATATTGGTGAAGGTGATTTTCTC
TATTTGGCCAGTGTCTCCCTCATTTTCCCATTTTCCAAAATACTAATAGCTATTGAACTAGCTTGCTCATTTGGGCTTAT
GTACTTCCTAGTACGTAAAAACCCTAATGAAACAGTCGCTTTTGTCCCATTTCTCTTTATGAGTGTTCTAATTCTTACCT
TCATGTAA

Domains

Predicted by InterProScan.

Bacterial Peptidase A24 N-terminal domain (A24_N_bact)

(9-89)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q5M4Y9

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cclA/cilC Streptococcus mitis SK321

39.72

99.535

0.395
  cclA/cilC Streptococcus pneumoniae TIGR4

39.72

99.535

0.395
  cclA/cilC Streptococcus mitis NCTC 12261

39.252

99.535

0.391
  cclA/cilC Streptococcus pneumoniae Rx1

38.785

99.535

0.386
  cclA/cilC Streptococcus pneumoniae D39

38.785

99.535

0.386
  cclA/cilC Streptococcus pneumoniae R6

38.785

99.535

0.386

Multiple sequence alignment