Detailed information    

insolico Bioinformatically predicted

Overview

Name   cclA/cilC   Type   Machinery gene
Locus tag   H1W94_RS03680 Genome accession   NZ_LR822041
Coordinates   689303..689950 (-) Length   215 a.a.
NCBI ID   WP_002950388.1    Uniprot ID   Q5M4Y9
Organism   Streptococcus thermophilus isolate STH_CIRM_1122     
Function   processing and translocation of ComGC; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 684303..694950
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H1W94_RS03665 (STHERMO_0774) holA 686053..687087 (+) 1035 WP_011227067.1 DNA polymerase III subunit delta -
  H1W94_RS03670 (STHERMO_0775) sodA 687182..687787 (+) 606 WP_011680996.1 superoxide dismutase SodA -
  H1W94_RS03675 (STHERMO_0776) - 687884..689263 (+) 1380 WP_082302965.1 serine hydrolase -
  H1W94_RS03680 (STHERMO_0777) cclA/cilC 689303..689950 (-) 648 WP_002950388.1 prepilin peptidase Machinery gene
  H1W94_RS03685 (STHERMO_0778) - 690059..690580 (+) 522 WP_011225768.1 Dps family protein -
  H1W94_RS03690 (STHERMO_0779) - 690669..691106 (+) 438 WP_011227072.1 Fur family transcriptional regulator -
  H1W94_RS03695 (STHERMO_0780) - 691217..691423 (+) 207 WP_002950395.1 YqgQ family protein -
  H1W94_RS03700 (STHERMO_0781) - 691416..692384 (+) 969 WP_180478558.1 ROK family glucokinase -
  H1W94_RS03705 (STHERMO_0782) typA 692522..694369 (+) 1848 WP_156703460.1 translational GTPase TypA -
  H1W94_RS03710 (STHERMO_0783) - 694393..694665 (+) 273 WP_002950398.1 DUF3165 family protein -

Sequence

Protein


Download         Length: 215 a.a.        Molecular weight: 24887.00 Da        Isoelectric Point: 8.3836

>NTDB_id=1011655 H1W94_RS03680 WP_002950388.1 689303..689950(-) (cclA/cilC) [Streptococcus thermophilus isolate STH_CIRM_1122]
MLSILYFFLGTSLGSFIGLICDRFPEKSIIFPRSHCNQCGHPLRFFEMIPILSQLFLRFKCRLCQSSIPYRYLFLELFCG
GILLLYFYDYLDFGRTYLLFFSLCLTIFDLKNKSYPLLIWILGTLPLLCLGNHYLTFSLGISLAVLSYIKRLNIGEGDFL
YLASVSLIFPFSKILIAIELACSFGLMYFLVRKNPNETVAFVPFLFMSVLILTFM

Nucleotide


Download         Length: 648 bp        

>NTDB_id=1011655 H1W94_RS03680 WP_002950388.1 689303..689950(-) (cclA/cilC) [Streptococcus thermophilus isolate STH_CIRM_1122]
ATGCTTAGTATTTTATATTTTTTTCTTGGTACCTCTTTAGGCTCGTTTATTGGATTGATTTGTGATCGTTTTCCTGAGAA
GTCGATTATTTTTCCTAGAAGCCATTGCAATCAGTGTGGGCATCCGTTACGTTTTTTCGAAATGATTCCGATCCTATCAC
AACTTTTCTTAAGGTTCAAATGTCGGTTATGTCAAAGCTCTATCCCATACCGTTACCTCTTCTTGGAATTGTTTTGTGGA
GGAATACTTCTTCTTTATTTCTATGACTACCTAGATTTCGGAAGAACCTATTTGCTTTTTTTCAGTCTTTGTCTAACTAT
TTTTGATTTAAAAAATAAATCATATCCCCTTCTAATTTGGATTCTTGGAACACTACCTCTCCTATGTTTGGGAAACCACT
ACCTCACTTTTAGCTTAGGAATAAGTTTAGCCGTTCTGTCATATATCAAACGTTTAAATATTGGTGAAGGTGATTTTCTC
TATTTGGCCAGTGTCTCCCTCATTTTCCCATTTTCCAAAATACTAATAGCTATTGAACTAGCTTGCTCATTTGGGCTTAT
GTACTTCCTAGTACGTAAAAACCCTAATGAAACAGTCGCTTTTGTCCCATTTCTCTTTATGAGTGTTCTAATTCTTACCT
TCATGTAA

Domains

Predicted by InterProScan.

Bacterial Peptidase A24 N-terminal domain (A24_N_bact)

(9-89)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q5M4Y9

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cclA/cilC Streptococcus mitis SK321

39.72

99.535

0.395
  cclA/cilC Streptococcus pneumoniae TIGR4

39.72

99.535

0.395
  cclA/cilC Streptococcus mitis NCTC 12261

39.252

99.535

0.391
  cclA/cilC Streptococcus pneumoniae Rx1

38.785

99.535

0.386
  cclA/cilC Streptococcus pneumoniae D39

38.785

99.535

0.386
  cclA/cilC Streptococcus pneumoniae R6

38.785

99.535

0.386