Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB   Type   Regulator
Locus tag   H1W91_RS08075 Genome accession   NZ_LR822032
Coordinates   1544270..1545637 (-) Length   455 a.a.
NCBI ID   WP_180477149.1    Uniprot ID   -
Organism   Streptococcus thermophilus isolate STH_CIRM_1050     
Function   transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 1539270..1550637
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H1W91_RS08050 (STHERMO_1762) - 1539620..1539886 (-) 267 WP_180477147.1 Blp family class II bacteriocin -
  H1W91_RS10445 (STHERMO_1763) - 1540137..1540538 (-) 402 WP_311316656.1 hypothetical protein -
  H1W91_RS08055 (STHERMO_1767) - 1541525..1541755 (-) 231 WP_011226494.1 bacteriocin class II family protein -
  H1W91_RS08060 (STHERMO_1768) - 1542005..1542736 (+) 732 WP_180477148.1 LytR/AlgR family response regulator transcription factor -
  H1W91_RS10150 comD/blpH 1543273..1544076 (+) 804 WP_224103634.1 ATP-binding protein Regulator
  H1W91_RS08070 (STHERMO_1770) - 1544094..1544255 (-) 162 WP_011226496.1 ComC/BlpC family leader-containing pheromone/bacteriocin -
  H1W91_RS08075 (STHERMO_1771) comB 1544270..1545637 (-) 1368 WP_180477149.1 bacteriocin secretion accessory protein Regulator
  H1W91_RS08080 - 1545653..1547806 (-) 2154 Protein_1541 peptide cleavage/export ABC transporter -
  H1W91_RS08085 (STHERMO_1777) - 1548820..1550565 (-) 1746 WP_180477150.1 ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 455 a.a.        Molecular weight: 50383.10 Da        Isoelectric Point: 4.7492

>NTDB_id=1010853 H1W91_RS08075 WP_180477149.1 1544270..1545637(-) (comB) [Streptococcus thermophilus isolate STH_CIRM_1050]
MNPQLFKSTEFYHRRYHNMSTVLITPLILLVIFLFLFAFFAKKEVTVTSRGSIEPTKIIAVIQSTSDNTIIDNQLVANKV
VKKGDTLVQYSETMEASQKEGLQKQLELLKRQESGLKTLQSSLTQGTNLFQEQEDEFGYQSTFNTYLSQAQDIDLGVAKT
NTEVNNQAAIASNTGSAIDNQISQLQTQVSEYEALSQAITNHETTLPEGNPHQATLNAYNSQYATTPDASVTDQYLSQVN
TNISSLNASIGNLEIQKAGTGTVVTYDNSDSTKKEALKNQFLQNAGQQLSSVETQITDTESKINQADVLLTNTLIQSPED
GILHLSQADKKATMAATGTELAQLYPDMTQTQEVAITYYVNSDYVPKLQKGQSVRLTLDKVGNHGTTIIGKLESIDNSAT
ETERGNVFRVTARASISEKEAQNLRYGLEGRVTSVIDQKTYFNYFKDKLLNLQDQ

Nucleotide


Download         Length: 1368 bp        

>NTDB_id=1010853 H1W91_RS08075 WP_180477149.1 1544270..1545637(-) (comB) [Streptococcus thermophilus isolate STH_CIRM_1050]
ATGAATCCACAGTTGTTTAAAAGCACAGAGTTTTACCATCGTCGCTACCACAATATGTCTACTGTTTTGATTACTCCCTT
GATTTTGTTAGTTATTTTCCTTTTTCTTTTCGCTTTTTTTGCTAAGAAGGAAGTTACAGTCACGTCTAGAGGAAGTATAG
AGCCAACCAAGATTATCGCAGTAATCCAATCAACCAGTGACAATACCATCATAGATAATCAACTGGTTGCTAATAAGGTT
GTTAAAAAAGGGGACACCTTAGTTCAGTATTCAGAGACCATGGAGGCATCGCAAAAAGAGGGGCTTCAAAAGCAACTAGA
ACTTTTAAAAAGACAGGAATCAGGTTTGAAGACCTTGCAATCTAGCCTAACGCAGGGAACCAATCTTTTCCAAGAACAGG
AAGACGAGTTTGGTTATCAGAGTACTTTTAACACCTACCTAAGTCAGGCACAGGATATTGACTTGGGTGTGGCTAAAACA
AATACAGAGGTTAATAACCAAGCAGCAATTGCGAGTAATACCGGTTCTGCTATTGATAACCAGATTAGTCAATTGCAGAC
TCAGGTCTCAGAGTATGAGGCGCTCTCTCAAGCTATTACCAATCATGAAACGACTTTACCTGAAGGCAATCCTCATCAGG
CAACCTTAAATGCCTATAACAGTCAGTATGCTACGACACCGGATGCCAGTGTAACAGACCAATACCTATCTCAAGTTAAT
ACCAATATTTCGAGCTTGAATGCTTCCATAGGTAATCTAGAAATCCAAAAGGCTGGGACAGGCACAGTTGTAACTTATGA
CAATAGTGATAGCACTAAAAAAGAAGCTCTAAAAAATCAATTCTTGCAAAATGCAGGACAGCAATTGAGCTCAGTGGAAA
CACAAATTACCGATACCGAGAGTAAAATCAATCAGGCAGATGTCCTTCTGACTAATACCCTCATCCAGTCACCAGAAGAT
GGAATCTTACACTTGAGTCAAGCTGATAAAAAAGCAACCATGGCTGCGACAGGAACTGAGTTGGCCCAGCTTTATCCCGA
TATGACTCAAACCCAGGAAGTTGCCATTACTTATTATGTGAATTCGGATTATGTGCCAAAACTGCAAAAAGGCCAGTCAG
TTCGACTGACCTTGGATAAGGTTGGTAATCACGGTACCACAATTATTGGAAAACTTGAGAGTATTGATAATTCTGCCACG
GAAACAGAAAGGGGGAATGTGTTTAGAGTAACTGCTAGGGCAAGTATTTCAGAAAAAGAAGCCCAAAATCTACGTTACGG
TCTAGAAGGTCGTGTGACAAGCGTTATTGACCAAAAGACCTACTTCAATTACTTTAAAGACAAGTTACTAAACTTGCAAG
ACCAATAG

Domains

Predicted by InterProScan.

HlyD family secretion protein ()

(315-427)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB Streptococcus pneumoniae Rx1

39.69

99.121

0.393
  comB Streptococcus pneumoniae D39

39.69

99.121

0.393
  comB Streptococcus pneumoniae R6

39.69

99.121

0.393
  comB Streptococcus pneumoniae TIGR4

39.024

99.121

0.387
  comB Streptococcus mitis SK321

38.359

99.121

0.38
  comB Streptococcus mitis NCTC 12261

38.359

99.121

0.38

Multiple sequence alignment