Detailed information NTG1010259

Bioinformatically predicted

Overview

• Name: comR
• Type: Regulator
• Locus tag: H1W98_RS01565
• Genome accession: NZ_LR822026
• Coordinates: 292072..292971 (+)
• Length: 299 a.a.
• NCBI ID: WP_084825763.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus isolate STH_CIRM_967
• Function: activate transcription of comX; activate transcription of comS (predicted from homology) Competence regulation

Genomic Context

Location: 287072..297971

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
H1W98_RS01545 (STHERMO_0310)	-	288496..289035 (+)	540	WP_372585740.1	tRNA (cytidine(34)-2'-O)-methyltransferase	-
H1W98_RS01550 (STHERMO_0311)	-	289346..289903 (+)	558	WP_179972601.1	ECF transporter S component	-
H1W98_RS01555 (STHERMO_0312)	-	289906..290556 (+)	651	WP_179972602.1	phosphatase PAP2 family protein	-
H1W98_RS01560 (STHERMO_0314)	-	290726..291901 (-)	1176	WP_179972979.1	IS256-like element IS1191 family transposase	-
H1W98_RS01565 (STHERMO_0315)	comR	292072..292971 (+)	900	WP_084825763.1	helix-turn-helix domain-containing protein	Regulator
H1W98_RS11180	-	293146..295247 (+)	2102	Protein_266	peptide cleavage/export ABC transporter	-
H1W98_RS01575 (STHERMO_0319)	-	295374..295706 (+)	333	WP_180482249.1	DUF805 domain-containing protein	-
H1W98_RS10545 (STHERMO_0320)	-	295758..296012 (-)	255	WP_232086931.1	hypothetical protein	-
H1W98_RS11185	-	295984..296331 (-)	348	WP_232086208.1	DUF4153 domain-containing protein	-
H1W98_RS10550 (STHERMO_0322)	-	296256..296558 (-)	303	WP_232086872.1	hypothetical protein	-

Sequence

Protein

• Length: 299 a.a.
• Molecular weight: 35289.82 Da
• Isoelectric Point: 5.2314

>NTDB_id=1010259 H1W98_RS01565 WP_084825763.1 292072..292971(+) (comR) [Streptococcus thermophilus isolate STH_CIRM_967]
MNIKDSIGLRIKTERERQQMSREVLCLDGAELTVRQLIRIEKGESLPSLDRLSYIAKRLGKSMTELLDQDNITIPDEYYE
MKNRLIKFPTYRNPDRIKSKLTLIEEVYEKFFDILPEEELLTLDILENILSFTSWEESPKVEEIYEDLFEQVKKKRKFST
NDLLVIDYYFFHLYGRKQYDKKLFERIVKRVLNQEIWTDDVYNIVLFNDLMAIAALKIFHKSFSDFLTVIDKALAVIEKS
QLYSYKPSVFVLKAKYELLHKENKKEAAENYDKAIMFASVLEDSVLEESIKAGKLADGL

Nucleotide

• Length: 900 bp

>NTDB_id=1010259 H1W98_RS01565 WP_084825763.1 292072..292971(+) (comR) [Streptococcus thermophilus isolate STH_CIRM_967]
TTGAACATAAAAGACAGCATTGGATTAAGAATCAAAACTGAGCGTGAACGGCAACAGATGTCACGTGAAGTGCTATGTTT
AGATGGTGCGGAATTGACTGTTCGCCAGTTAATTCGTATTGAAAAGGGGGAGTCTCTCCCATCTTTAGATAGATTATCGT
ATATTGCTAAACGTTTAGGAAAAAGTATGACAGAGTTATTGGATCAAGACAATATTACCATTCCTGACGAATATTATGAA
ATGAAGAATCGTTTGATTAAGTTTCCAACGTACAGAAACCCTGACAGAATAAAGTCTAAACTTACTTTGATTGAGGAAGT
CTATGAGAAATTTTTTGATATTCTTCCAGAAGAAGAATTATTAACTCTAGACATTCTCGAAAATATATTGAGTTTTACTA
GCTGGGAGGAGAGTCCAAAGGTTGAGGAAATATACGAGGACTTGTTTGAACAAGTCAAAAAGAAGAGGAAGTTCTCGACT
AACGATTTATTAGTCATTGACTATTATTTCTTTCATCTTTATGGGAGAAAACAGTATGACAAAAAACTATTTGAAAGAAT
TGTAAAGAGAGTATTAAATCAGGAAATTTGGACAGATGATGTTTACAATATTGTTTTATTTAATGATTTGATGGCTATTG
CTGCTTTAAAGATTTTTCATAAGTCCTTCTCAGACTTCTTAACAGTTATAGATAAAGCATTAGCTGTCATAGAAAAATCA
CAATTATATAGCTACAAGCCTAGTGTTTTTGTACTTAAGGCTAAATATGAACTTCTGCATAAAGAAAACAAGAAAGAGGC
TGCAGAGAATTATGATAAGGCCATAATGTTTGCTTCCGTTTTGGAAGACTCGGTTTTAGAGGAAAGTATAAAGGCAGGAA
AATTGGCAGATGGTTTATAG

Domains

Predicted by InterProScan.

• Helix-turn-helix (HTH_3) (11-66)

• ComR tetratricopeptide (ComR_TPR) (75-292)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comR	Streptococcus thermophilus LMG 18311	98.662	100	0.987
comR	Streptococcus thermophilus LMD-9	97.993	100	0.98
comR	Streptococcus salivarius strain HSISS4	94.649	100	0.946
comR	Streptococcus salivarius SK126	93.98	100	0.94
comR/comR1	Streptococcus sobrinus strain NIDR 6715-7	42.475	100	0.425
comR/comR2	Streptococcus sobrinus strain NIDR 6715-7	42.475	100	0.425