Detailed information NTG1009874

Bioinformatically predicted

Overview

• Name: comEC/celB
• Type: Machinery gene
• Locus tag: H0510_RS07080
• Genome accession: NZ_LR822019
• Coordinates: 1358323..1360563 (-)
• Length: 746 a.a.
• NCBI ID: WP_179966748.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus isolate STH_CIRM_772
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1353323..1365563

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
H0510_RS07060 (STHERMO_1562)	-	1354187..1355047 (-)	861	WP_011227466.1	methionyl aminopeptidase	-
H0510_RS07065 (STHERMO_1563)	spxR	1355091..1356371 (-)	1281	WP_096811595.1	CBS-HotDog domain-containing transcription factor SpxR	-
H0510_RS07070 (STHERMO_1564)	-	1356364..1356909 (-)	546	WP_022096992.1	GNAT family N-acetyltransferase	-
H0510_RS07075 (STHERMO_1565)	-	1356975..1358237 (-)	1263	WP_022096991.1	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	-
H0510_RS07080 (STHERMO_1566)	comEC/celB	1358323..1360563 (-)	2241	WP_179966748.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
H0510_RS07085 (STHERMO_1567)	comEA	1360553..1361248 (-)	696	WP_179966749.1	helix-hairpin-helix domain-containing protein	Machinery gene
H0510_RS07090 (STHERMO_1568)	-	1361356..1362111 (-)	756	WP_002948862.1	lysophospholipid acyltransferase family protein	-
H0510_RS09655 (STHERMO_1569)	-	1362311..1362847 (+)	537	WP_232086644.1	polysaccharide deacetylase family protein	-
H0510_RS09660 (STHERMO_1570)	-	1362888..1363175 (+)	288	WP_096811598.1	peptidoglycan GlcNAc deacetylase	-
H0510_RS07100 (STHERMO_1571)	-	1363225..1363977 (+)	753	WP_002948852.1	tRNA1(Val) (adenine(37)-N6)-methyltransferase	-
H0510_RS07105 (STHERMO_1572)	-	1363994..1364263 (+)	270	WP_179966750.1	GIY-YIG nuclease family protein	-

Sequence

Protein

• Length: 746 a.a.
• Molecular weight: 84859.79 Da
• Isoelectric Point: 9.9240

>NTDB_id=1009874 H0510_RS07080 WP_179966748.1 1358323..1360563(-) (comEC/celB) [Streptococcus thermophilus isolate STH_CIRM_772]
MWLKKAPINLFSLALLIVALYFTIFVSNFYAIGTFVFLMICFLRHHWKNRAALKLVGLIGGFFLVYFLFLYHIAIMQDKQ
APAEIHQVTLVADTLSVNGERLSAIGKSNGQTYQVFYRLKSDKEQHFFKTTSQTLVLKGKIKLSSATGQRNFQGFDYQSY
LASQGIYRIAQIDRLEHVVTPKSISPIAFFHQLRRKALVHIQTHFPNPMRHYMTGLLFGYLDKEFDEQSQLYTSLGIIHL
FALSGMQVGFFLGWFRYGLLRLGLPKNYILAILLPFSIFYGLMTGWTASVLRSLIQSLLAECGIKKLNNMGITLLLFFLV
LPHFLLTVGGVLSCSYSFLLCLFNFEEMPSFKKSIYMSLVLSLGTLPFLTYYYGTFQPLSLILTAIFSLVFDSFLLPVLT
VLFTLSGMVIFSQFNTLFEWMEFFLTWVQSWGVQPLILGKPSLFQFVSMIFVLVFLFDFWKKPQFRISLLMIFSLLMVWV
KHPLINEVTVVDVGQGDSIFLRSMKGETVLIDVGGKVTFGSKEKWQEGSQTSNAEKTLIPYLQARGVSQIDYLVLTHTDT
DHIGDLEVVAKRFKIKKICVSEGALTKPSFAKRIRFLKCPVRTLKAGDKLPMMGSNLQVLYPNKIGDGGNNDSLVLYGKL
LGTSFLFTGDLEKEGEEELMTSYPNLKVRVLKAGHHGSKGSSSEAFLDQLKPSLALVSAGENNRYKHPNDETLERFKERH
IKVLRTDQDGAIRFKGWFQLSSETVR

Nucleotide

• Length: 2241 bp

>NTDB_id=1009874 H0510_RS07080 WP_179966748.1 1358323..1360563(-) (comEC/celB) [Streptococcus thermophilus isolate STH_CIRM_772]
ATGTGGCTTAAAAAAGCTCCAATCAATCTTTTTTCCCTAGCGCTTTTAATAGTTGCTCTTTATTTTACTATTTTTGTATC
TAATTTCTATGCTATTGGGACTTTTGTCTTTCTGATGATATGTTTTTTGAGGCATCATTGGAAGAATAGAGCAGCTCTAA
AGTTGGTGGGACTTATAGGTGGTTTCTTTTTGGTCTACTTTTTATTTTTGTACCATATAGCTATCATGCAAGATAAACAA
GCTCCTGCTGAAATTCATCAGGTGACACTGGTTGCAGATACGCTCTCAGTTAATGGTGAGCGATTATCAGCAATCGGGAA
GTCAAATGGACAAACCTATCAGGTCTTTTACCGGCTAAAATCTGATAAGGAGCAGCATTTTTTTAAGACTACTAGTCAAA
CGCTTGTTTTAAAAGGGAAAATAAAGTTGTCCTCGGCAACTGGTCAACGTAATTTTCAAGGATTTGATTATCAGTCTTAT
CTAGCTAGTCAGGGCATTTATAGGATTGCTCAGATTGACCGTCTGGAACATGTCGTAACCCCAAAATCGATATCTCCAAT
AGCTTTTTTTCATCAATTGAGGAGGAAGGCTCTAGTTCATATTCAGACGCATTTTCCTAATCCGATGAGACACTACATGA
CAGGACTGCTCTTTGGGTATTTGGACAAGGAGTTTGATGAGCAGAGTCAACTCTACACTAGCTTGGGGATTATTCATCTT
TTTGCGCTATCGGGTATGCAGGTTGGATTTTTTCTTGGCTGGTTTCGCTATGGACTTCTCCGTTTGGGGCTTCCCAAAAA
TTATATCCTTGCTATCTTATTACCTTTTTCGATTTTCTATGGCTTAATGACTGGTTGGACGGCTTCGGTCTTACGTTCTT
TGATTCAAAGCCTCTTGGCTGAGTGTGGTATTAAAAAACTGAACAATATGGGCATAACGCTACTTCTATTTTTTCTAGTC
TTGCCTCATTTTCTTTTAACGGTAGGAGGTGTTTTAAGTTGTTCTTATTCCTTCTTGTTGTGTTTATTTAATTTTGAGGA
GATGCCGTCCTTTAAAAAGTCAATTTATATGAGTTTAGTATTGAGTCTTGGGACTTTGCCTTTTTTGACCTACTATTATG
GAACTTTTCAACCATTGAGTTTGATTCTGACGGCAATCTTCTCTCTAGTTTTTGATAGCTTTCTCTTACCTGTCTTAACA
GTACTTTTTACACTTTCAGGAATGGTAATTTTTTCTCAATTTAACACACTTTTTGAATGGATGGAGTTCTTTTTGACTTG
GGTACAATCTTGGGGAGTCCAGCCATTGATTTTAGGAAAACCTAGCTTGTTTCAGTTTGTCTCAATGATATTTGTATTGG
TTTTTCTCTTTGATTTTTGGAAAAAGCCTCAGTTTAGAATATCCCTCTTGATGATTTTTAGTCTTTTGATGGTCTGGGTC
AAACATCCTTTAATAAATGAAGTAACGGTGGTCGACGTTGGTCAAGGAGATAGTATTTTTTTAAGGAGTATGAAAGGTGA
AACGGTCCTAATAGATGTAGGTGGCAAGGTGACTTTCGGCTCTAAGGAAAAATGGCAAGAGGGGAGCCAGACGAGTAATG
CGGAGAAAACCTTAATTCCCTATCTACAGGCAAGGGGAGTGTCTCAAATTGACTATCTGGTTCTGACTCATACGGATACA
GACCATATTGGTGATTTGGAGGTAGTGGCTAAACGGTTTAAGATTAAGAAAATTTGTGTCAGTGAGGGGGCTTTGACTAA
GCCTAGTTTTGCCAAACGTATTCGATTTCTTAAATGTCCCGTTCGCACTTTAAAGGCTGGTGATAAGCTGCCTATGATGG
GAAGTAACCTACAGGTTCTTTATCCCAATAAAATTGGTGATGGTGGTAACAATGATTCACTTGTTCTCTATGGAAAGTTA
TTGGGAACCAGTTTTCTATTTACTGGTGATTTGGAAAAAGAAGGAGAAGAGGAATTGATGACTAGCTATCCAAATTTAAA
AGTAAGGGTCCTCAAAGCAGGACATCACGGTTCTAAAGGCTCTTCATCAGAAGCTTTTTTGGATCAGCTAAAGCCATCAC
TTGCTCTTGTCTCAGCAGGTGAAAATAATCGTTATAAGCATCCAAATGATGAAACATTAGAGCGTTTCAAAGAACGTCAC
ATTAAGGTTTTACGCACAGACCAGGATGGTGCCATTCGGTTTAAGGGATGGTTCCAACTATCAAGTGAAACTGTCCGATA
A

Domains

Predicted by InterProScan.

• Competence protein (Competence) (216-462)

• Domain of unknown function (DUF4131) (DUF4131) (29-170)

• Metallo-beta-lactamase superfamily (Lactamase_B) (492-699)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC/celB	Streptococcus mitis NCTC 12261	47.453	100	0.475
comEC/celB	Streptococcus mitis SK321	46.586	100	0.466
comEC/celB	Streptococcus pneumoniae TIGR4	45.649	100	0.457
comEC/celB	Streptococcus pneumoniae D39	45.382	100	0.454
comEC/celB	Streptococcus pneumoniae Rx1	45.382	100	0.454
comEC/celB	Streptococcus pneumoniae R6	45.382	100	0.454
comEC	Lactococcus lactis subsp. cremoris KW2	45.103	97.185	0.438