Detailed information NTG1009771

Bioinformatically predicted

Overview

• Name: comEC/celB
• Type: Machinery gene
• Locus tag: H0511_RS07245
• Genome accession: NZ_LR822017
• Coordinates: 1424722..1426962 (-)
• Length: 746 a.a.
• NCBI ID: WP_179973926.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus isolate STH_CIRM_336
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1419722..1431962

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
H0511_RS07225 (STHERMO_1621)	-	1420586..1421446 (-)	861	WP_179973925.1	methionyl aminopeptidase	-
H0511_RS07230 (STHERMO_1622)	spxR	1421490..1422770 (-)	1281	WP_179972170.1	CBS-HotDog domain-containing transcription factor SpxR	-
H0511_RS07235	-	1422763..1423308 (-)	546	Protein_1391	GNAT family N-acetyltransferase	-
H0511_RS07240 (STHERMO_1625)	-	1423374..1424636 (-)	1263	WP_179972171.1	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	-
H0511_RS07245 (STHERMO_1626)	comEC/celB	1424722..1426962 (-)	2241	WP_179973926.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
H0511_RS07250 (STHERMO_1627)	comEA	1426952..1427647 (-)	696	WP_179973927.1	helix-hairpin-helix domain-containing protein	Machinery gene
H0511_RS07255 (STHERMO_1628)	-	1427753..1428508 (-)	756	WP_179973928.1	lysophospholipid acyltransferase family protein	-
H0511_RS10620 (STHERMO_1629)	-	1428602..1428808 (+)	207	WP_232087319.1	hypothetical protein	-
H0511_RS10130 (STHERMO_1630)	-	1428911..1429549 (+)	639	WP_269473445.1	polysaccharide deacetylase family protein	-
H0511_RS07265 (STHERMO_1631)	-	1429599..1430363 (+)	765	WP_179972175.1	tRNA1(Val) (adenine(37)-N6)-methyltransferase	-
H0511_RS07270 (STHERMO_1632)	-	1430367..1430636 (+)	270	WP_179972176.1	GIY-YIG nuclease family protein	-

Sequence

Protein

• Length: 746 a.a.
• Molecular weight: 85094.12 Da
• Isoelectric Point: 9.9593

>NTDB_id=1009771 H0511_RS07245 WP_179973926.1 1424722..1426962(-) (comEC/celB) [Streptococcus thermophilus isolate STH_CIRM_336]
MWLKKSPINLFSLALLIVALYFTIFVSNFYAIGTFVFLMICFLRHHWKNRATLKLVGLVGGFFLVYFLFLYHIAIMQDKQ
APAEIHQVTLVADTLSVNGERLSAIGKSNGQTYQVFYRLKSDKEKHFFKTTSQTLVLKGKIKLSSATGQRNFQGFDYQSY
LASQGIYRIAQIERLEHVVTPKSISPIAFFHQLRRRALVHIQTHFPNPMRHYMTGLLFGYLDKEFDEQSQLYTSLGIIHL
FALSGMQVGFFLGWFRYGLLRLGLPKNYILTILLPFSIFYGLMTGWTASVLRSLIQSLLSECGIKKLNNMGITLLLFFLV
LPHFLLTVGGVLSCSYAFLLCLFNFEEMPSFKKSIYMSLVLSLGTLPFLTYYYGTFQPLSLILTAIFSLVFDSFLLPVLT
VLFTLSGMVIFSQFNPLFEWMEFFLTWVQSWGVQPLILGKPSLFQFVLMIFVLVLLFDFWKKPQFRISLLMIFSLLMVWV
KHPLINEVTVVDVGQGDSIFLRSMKGETVLIDVGGKVTFVSKEKWQEGSQTSNAEKTLIPYLQERGVSQIDYLVLTHTDT
DHIGDLEEVAKRFKIKEICVSKGALTKPSFAKRIRFLKRPVRTLKAGDKLTMMGSNLQVLYPNKIGDGGNNDSLVLYGKL
LGTSFLFTGDLEKEGEEELMASYPNLKVRVLKAGHHGSKGSSSEAFLDQLKPSLALVSAGENNRYKHPNDETLERFKERH
IKVLRTDLDGAIRFKGWFQLSSETVR

Nucleotide

• Length: 2241 bp

>NTDB_id=1009771 H0511_RS07245 WP_179973926.1 1424722..1426962(-) (comEC/celB) [Streptococcus thermophilus isolate STH_CIRM_336]
ATGTGGCTTAAAAAATCTCCAATCAATCTTTTTTCCCTAGCGCTTTTAATAGTTGCTCTTTATTTTACTATTTTTGTATC
TAATTTCTATGCTATTGGGACTTTTGTCTTTCTGATGATATGTTTTTTGAGGCATCATTGGAAGAATAGAGCAACTCTAA
AGTTGGTGGGACTTGTAGGTGGTTTCTTTTTGGTCTACTTTTTATTTTTATACCATATAGCTATCATGCAAGATAAACAG
GCTCCTGCTGAAATTCATCAGGTGACACTGGTTGCAGATACGCTCTCAGTTAATGGTGAGCGATTATCAGCAATCGGGAA
GTCAAATGGACAAACCTATCAGGTCTTTTACCGGCTAAAATCTGATAAGGAGAAGCATTTTTTTAAGACTACTAGTCAAA
CGCTTGTTTTAAAAGGGAAAATAAAGTTGTCCTCGGCAACTGGTCAACGTAATTTTCAAGGCTTTGATTATCAGTCTTAT
CTAGCTAGTCAGGGCATTTATAGGATTGCTCAGATTGAGCGTCTGGAACATGTCGTAACCCCAAAATCGATATCTCCAAT
AGCTTTTTTCCATCAATTGAGGAGGAGGGCTCTAGTTCATATTCAGACGCATTTTCCTAATCCGATGAGACACTACATGA
CAGGACTGCTCTTTGGGTATTTGGACAAGGAGTTTGATGAGCAGAGTCAACTCTACACCAGCTTGGGGATTATTCATCTT
TTTGCGCTATCGGGTATGCAGGTTGGATTTTTTCTTGGCTGGTTTCGCTATGGACTTCTCCGTTTGGGGCTTCCCAAAAA
TTATATCCTTACTATCTTATTACCTTTTTCGATTTTCTATGGCTTAATGACTGGTTGGACGGCTTCGGTCTTACGTTCTT
TGATTCAAAGCCTCTTGTCTGAGTGTGGTATTAAAAAACTGAACAATATGGGCATAACGCTACTTCTATTTTTTCTAGTC
TTGCCTCATTTTCTTTTAACGGTAGGAGGTGTTTTAAGTTGTTCTTATGCCTTCTTGTTGTGTTTATTTAATTTTGAGGA
GATGCCGTCCTTTAAAAAGTCAATTTATATGAGTTTGGTATTGAGTCTTGGGACTTTGCCTTTTTTGACCTACTATTATG
GAACTTTTCAACCATTGAGTTTGATTCTGACGGCAATCTTCTCTCTAGTTTTTGATAGCTTTCTCTTACCTGTCTTAACA
GTACTTTTTACACTTTCAGGAATGGTAATTTTTTCTCAATTTAACCCACTTTTTGAATGGATGGAGTTCTTTTTGACTTG
GGTACAATCTTGGGGAGTCCAGCCATTGATTTTAGGAAAACCTAGCTTGTTTCAGTTTGTCTTGATGATATTTGTATTGG
TTTTGCTCTTTGATTTTTGGAAAAAGCCTCAGTTTAGAATATCCCTCTTGATGATTTTTAGTCTTTTGATGGTCTGGGTC
AAACATCCTTTAATAAATGAAGTAACGGTGGTCGACGTTGGTCAAGGAGATAGTATTTTTTTAAGGAGTATGAAAGGTGA
GACGGTCCTAATAGATGTAGGTGGCAAGGTGACTTTCGTCTCTAAGGAAAAATGGCAAGAGGGGAGCCAGACGAGTAATG
CGGAGAAAACCTTAATTCCCTATTTACAGGAAAGGGGAGTGTCTCAAATTGACTATCTGGTTCTGACTCATACGGATACA
GATCATATTGGTGATTTGGAGGAAGTGGCTAAACGGTTTAAGATTAAGGAAATTTGTGTCAGTAAGGGGGCTTTGACTAA
GCCTAGTTTTGCCAAACGTATTCGATTTCTTAAACGTCCCGTTCGCACTTTAAAGGCTGGTGATAAGCTGACTATGATGG
GAAGTAACCTACAGGTTCTTTATCCTAATAAAATTGGTGATGGTGGTAACAATGATTCACTTGTTCTCTATGGAAAGTTA
TTGGGAACCAGTTTTTTGTTTACTGGTGATTTAGAAAAAGAAGGAGAGGAGGAATTAATGGCTAGCTATCCAAATTTAAA
AGTAAGGGTCCTAAAAGCAGGACATCACGGTTCTAAAGGCTCTTCATCAGAAGCTTTTTTGGATCAGCTAAAGCCATCAC
TTGCTCTTGTCTCAGCTGGTGAAAATAATCGTTATAAGCATCCAAATGATGAAACATTAGAGCGTTTCAAAGAACGTCAC
ATTAAGGTTTTACGCACAGACCTGGATGGTGCCATTCGGTTTAAGGGATGGTTCCAACTATCAAGTGAAACTGTCCGATA
A

Domains

Predicted by InterProScan.

• Competence protein (Competence) (216-462)

• Metallo-beta-lactamase superfamily (Lactamase_B) (492-699)

• Domain of unknown function (DUF4131) (DUF4131) (29-170)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC/celB	Streptococcus mitis NCTC 12261	47.855	100	0.479
comEC/celB	Streptococcus mitis SK321	46.854	100	0.469
comEC/celB	Streptococcus pneumoniae TIGR4	46.051	100	0.461
comEC/celB	Streptococcus pneumoniae Rx1	45.783	100	0.458
comEC/celB	Streptococcus pneumoniae D39	45.783	100	0.458
comEC/celB	Streptococcus pneumoniae R6	45.783	100	0.458
comEC	Lactococcus lactis subsp. cremoris KW2	44.337	97.051	0.43