Detailed information NTG1009078

Bioinformatically predicted

Overview

• Name: comD/comD2
• Type: Regulator
• Locus tag: ABKA15_RS00035
• Genome accession: NZ_CP157941
• Coordinates: 3541..4827 (+)
• Length: 428 a.a.
• NCBI ID: WP_225620268.1
• Uniprot ID: -
• Organism: Streptococcus sp. KHUD_010
• Function: phosphorylation of ComE (predicted from homology) Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
IScluster/Tn	5683..6628	3541..4827	flank	856

Gene organization within MGE regions

Location: 3541..6628

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ABKA15_RS00035 (ABKA15_00035)	comD/comD2	3541..4827 (+)	1287	WP_225620268.1	GHKL domain-containing protein	Regulator
ABKA15_RS00040 (ABKA15_00040)	comE	4827..5576 (+)	750	WP_049512713.1	competence system response regulator transcription factor ComE	Regulator
ABKA15_RS00045 (ABKA15_00045)	-	5683..6628 (+)	946	Protein_7	IS30 family transposase	-

Sequence

Protein

• Length: 428 a.a.
• Molecular weight: 50366.72 Da
• Isoelectric Point: 8.7165

>NTDB_id=1009078 ABKA15_RS00035 WP_225620268.1 3541..4827(+) (comD/comD2) [Streptococcus sp. KHUD_010]
MIEAVSVVYCYKKISRVNKVNIHFTLLCLGIVFSTDFTTLIHYSIRYMMFFIQPLFFYLYFFKVKKVKKHLSVFLALFLS
LAVSSSETFFSVIISSVTGDKFVDRYWGLFYIFINIISLVFILKAIDYFKFNFKYFKKADFKENIVQLNFYLLFIHFLLN
LSHWLSNMKNLNSFSSMIATICFLMFMSTLFYLQSIREKYEKEEQIKQKEREQLQLQKYTDEIVSLYNEIRGFRHDYGGM
LASFQSAIHTGDIKEVERIYQEVLVNANLQLRSDKYTYFDLNNVGDSALRSVMTQTLFKARDYNIELTFEVKDFVKPLPI
KLLDLVRMTSVLLNNAIEGAAESYQKTMNVSLVDLDTETILVIQNSRKKRPLDLEEIYQTDFSTKGEGRGLGLSNIKEII
NNYEGIILDTKIEDEYFTQVMRVRKEGL

Nucleotide

• Length: 1287 bp

>NTDB_id=1009078 ABKA15_RS00035 WP_225620268.1 3541..4827(+) (comD/comD2) [Streptococcus sp. KHUD_010]
ATTATAGAAGCTGTTTCTGTTGTATATTGCTATAAGAAAATAAGTAGAGTGAATAAAGTGAATATTCACTTTACTTTGTT
GTGTTTAGGAATTGTATTTTCAACTGATTTCACTACTTTAATACATTATTCCATTAGATATATGATGTTTTTTATTCAAC
CATTATTTTTTTATTTATATTTTTTTAAAGTAAAAAAAGTTAAAAAACATCTTTCTGTATTTTTAGCACTATTTTTATCT
TTAGCTGTGTCAAGTTCTGAAACCTTCTTTTCAGTCATTATTTCTTCTGTTACAGGTGATAAGTTTGTTGATAGATACTG
GGGATTGTTCTATATTTTTATCAATATCATTTCTTTAGTTTTTATTTTAAAAGCAATTGATTATTTTAAGTTTAATTTTA
AATATTTTAAAAAGGCGGATTTTAAAGAGAATATTGTGCAGTTAAACTTTTATCTCTTATTTATTCATTTTTTATTAAAT
TTGTCGCATTGGCTTAGTAATATGAAAAATTTAAATAGTTTTTCTAGTATGATTGCTACAATTTGCTTTTTAATGTTTAT
GTCAACTTTATTCTACTTACAATCTATTCGCGAAAAGTATGAAAAAGAAGAACAAATTAAACAGAAAGAACGAGAACAAC
TACAATTACAAAAATATACAGATGAAATAGTGAGTCTGTATAATGAAATTCGAGGCTTTCGGCATGATTATGGCGGAATG
TTGGCAAGCTTCCAATCGGCCATTCATACAGGTGATATAAAAGAAGTAGAACGAATTTATCAGGAGGTGCTAGTAAATGC
TAATTTACAACTTCGTTCAGATAAATATACGTATTTTGATTTAAATAATGTTGGAGATTCAGCACTTAGAAGTGTTATGA
CGCAAACATTATTTAAGGCACGTGATTACAATATAGAATTAACATTTGAAGTAAAAGATTTTGTCAAGCCCTTGCCGATT
AAATTGTTAGATCTGGTTAGAATGACAAGCGTCCTTTTGAATAATGCCATAGAAGGAGCAGCAGAAAGTTATCAAAAAAC
GATGAATGTTTCTTTGGTGGATTTAGATACAGAAACAATCTTAGTCATTCAAAATTCACGTAAGAAAAGACCGCTAGATT
TAGAAGAGATTTACCAAACTGATTTTTCAACAAAGGGTGAAGGACGCGGTTTAGGCTTAAGCAATATCAAAGAAATTATT
AACAACTATGAAGGAATTATCCTCGATACTAAAATTGAGGATGAATATTTTACACAAGTAATGAGAGTGCGGAAAGAAGG
TTTATAA

Domains

Predicted by InterproScan.

• GHKL domain (HATPase_c_5) (321-420)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comD/comD2	Streptococcus gordonii strain NCTC7865	54.649	100	0.563
comD/comD1	Streptococcus gordonii str. Challis substr. CH1	59.424	89.252	0.53
comD	Streptococcus mitis SK321	47.194	91.589	0.432
comD	Streptococcus mitis NCTC 12261	48.936	87.85	0.43
comD/comD2	Streptococcus pneumoniae TIGR4	48.138	87.85	0.423
comD/comD1	Streptococcus pneumoniae Rx1	47.606	87.85	0.418
comD/comD1	Streptococcus pneumoniae D39	47.606	87.85	0.418
comD/comD1	Streptococcus pneumoniae R6	47.606	87.85	0.418