Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGD   Type   Machinery gene
Locus tag   GPW48_RS00760 Genome accession   NZ_LR738720
Coordinates   116898..117305 (+) Length   135 a.a.
NCBI ID   WP_011921721.1    Uniprot ID   A0A0H3MT39
Organism   Streptococcus suis isolate GD-0001     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 111898..122305
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GPW48_RS00735 - 113306..113671 (+) 366 WP_002936568.1 DUF1033 family protein -
  GPW48_RS00740 - 113706..114649 (-) 944 Protein_109 S66 family peptidase -
  GPW48_RS00745 comGA 114735..115685 (+) 951 WP_011921718.1 competence type IV pilus ATPase ComGA Machinery gene
  GPW48_RS00750 comGB 115597..116634 (+) 1038 WP_255304289.1 competence type IV pilus assembly protein ComGB Machinery gene
  GPW48_RS00755 comGC 116636..116917 (+) 282 WP_011921720.1 competence type IV pilus major pilin ComGC Machinery gene
  GPW48_RS00760 comGD 116898..117305 (+) 408 WP_011921721.1 competence type IV pilus minor pilin ComGD Machinery gene
  GPW48_RS00765 comGE 117277..117570 (+) 294 WP_011921722.1 competence type IV pilus minor pilin ComGE Machinery gene
  GPW48_RS00770 comGF/cglF 117557..117991 (+) 435 WP_011922561.1 competence type IV pilus minor pilin ComGF Machinery gene
  GPW48_RS00775 comGG 117969..118379 (+) 411 WP_011921724.1 competence type IV pilus minor pilin ComGG Machinery gene
  GPW48_RS00780 comGH 118436..119389 (+) 954 WP_024406069.1 class I SAM-dependent methyltransferase Machinery gene
  GPW48_RS00785 - 119439..120626 (+) 1188 WP_012775473.1 acetate kinase -
  GPW48_RS00790 - 120940..121491 (+) 552 WP_012775474.1 folate family ECF transporter S component -

Sequence

Protein


Download         Length: 135 a.a.        Molecular weight: 15367.59 Da        Isoelectric Point: 8.3926

>NTDB_id=1006735 GPW48_RS00760 WP_011921721.1 116898..117305(+) (comGD) [Streptococcus suis isolate GD-0001]
MLRRKNKAFTLFESLLTLLVVSFLAVSLSGTVQTVFRSVQEEIFLWEFEAIYKDSQKLAASSHKKVNLAIGGQEVTNGYQ
AVEVPRNVEVLEEKTIQFEEDGGNSSLTKIRFHLSQKIVTYQLYIGSGRYKKTEE

Nucleotide


Download         Length: 408 bp        

>NTDB_id=1006735 GPW48_RS00760 WP_011921721.1 116898..117305(+) (comGD) [Streptococcus suis isolate GD-0001]
ATGCTACGGCGAAAAAATAAGGCTTTTACCCTGTTTGAAAGCCTGCTGACCTTGTTGGTTGTCAGTTTTTTAGCTGTTTC
CTTATCAGGAACAGTACAAACGGTCTTTCGGTCTGTTCAGGAAGAAATTTTTCTCTGGGAATTTGAGGCCATCTATAAAG
ACAGTCAGAAATTAGCAGCCAGTTCCCACAAAAAAGTGAACCTTGCTATCGGTGGACAGGAGGTTACAAATGGTTATCAG
GCTGTAGAGGTGCCCAGAAATGTAGAGGTCTTAGAGGAGAAAACTATTCAGTTTGAAGAAGATGGTGGAAATTCTTCTCT
GACCAAGATTCGTTTTCACCTTAGTCAAAAAATAGTCACGTATCAATTATATATAGGGAGTGGTCGCTATAAGAAAACAG
AAGAATAA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0H3MT39

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGD Streptococcus gordonii str. Challis substr. CH1

48.031

94.074

0.452
  comGD Streptococcus mutans UA140

46.512

95.556

0.444
  comGD Streptococcus mutans UA159

46.512

95.556

0.444
  comGD/cglD Streptococcus pneumoniae TIGR4

44.961

95.556

0.43
  comGD/cglD Streptococcus pneumoniae R6

44.961

95.556

0.43
  comGD/cglD Streptococcus pneumoniae Rx1

44.961

95.556

0.43
  comGD/cglD Streptococcus pneumoniae D39

44.961

95.556

0.43
  comGD/cglD Streptococcus mitis NCTC 12261

44.186

95.556

0.422
  comGD/cglD Streptococcus mitis SK321

43.411

95.556

0.415
  comGD Lactococcus lactis subsp. cremoris KW2

39.062

94.815

0.37

Multiple sequence alignment