Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGA   Type   Machinery gene
Locus tag   UXQ45_RS08175 Genome accession   NZ_CP157420
Coordinates   1673590..1674564 (-) Length   324 a.a.
NCBI ID   WP_000697221.1    Uniprot ID   -
Organism   Staphylococcus aureus strain BSN48-2     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1668590..1679564
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  UXQ45_RS08135 (UXQ45_008135) gcvT 1669091..1670182 (-) 1092 WP_000093349.1 glycine cleavage system aminomethyltransferase GcvT -
  UXQ45_RS08140 (UXQ45_008140) - 1670341..1670865 (-) 525 WP_001015120.1 shikimate kinase -
  UXQ45_RS08145 (UXQ45_008145) - 1670855..1671001 (-) 147 WP_001792109.1 hypothetical protein -
  UXQ45_RS08150 (UXQ45_008150) comGF 1671098..1671595 (-) 498 WP_001788897.1 competence type IV pilus minor pilin ComGF Machinery gene
  UXQ45_RS08155 (UXQ45_008155) comGE 1671513..1671812 (-) 300 WP_000844410.1 hypothetical protein Machinery gene
  UXQ45_RS08160 (UXQ45_008160) comGD 1671799..1672245 (-) 447 WP_001788899.1 competence type IV pilus minor pilin ComGD Machinery gene
  UXQ45_RS08165 (UXQ45_008165) comGC 1672223..1672534 (-) 312 WP_000472256.1 competence type IV pilus major pilin ComGC Machinery gene
  UXQ45_RS08170 (UXQ45_008170) comGB 1672548..1673618 (-) 1071 WP_000776422.1 competence type IV pilus assembly protein ComGB Machinery gene
  UXQ45_RS08175 (UXQ45_008175) comGA 1673590..1674564 (-) 975 WP_000697221.1 competence type IV pilus ATPase ComGA Machinery gene
  UXQ45_RS08180 (UXQ45_008180) - 1674616..1675239 (-) 624 WP_001223008.1 MBL fold metallo-hydrolase -
  UXQ45_RS08185 (UXQ45_008185) - 1675236..1675565 (-) 330 WP_001018871.1 MTH1187 family thiamine-binding protein -
  UXQ45_RS08190 (UXQ45_008190) - 1675565..1676551 (-) 987 WP_000161311.1 ROK family glucokinase -
  UXQ45_RS08195 (UXQ45_008195) - 1676548..1676751 (-) 204 WP_000087561.1 YqgQ family protein -
  UXQ45_RS08200 (UXQ45_008200) - 1676732..1678195 (-) 1464 WP_001017852.1 rhomboid family intramembrane serine protease -
  UXQ45_RS08205 (UXQ45_008205) - 1678207..1678746 (-) 540 WP_000164546.1 5-formyltetrahydrofolate cyclo-ligase -
  UXQ45_RS08210 (UXQ45_008210) rpmG 1678955..1679104 (-) 150 WP_001265709.1 50S ribosomal protein L33 -

Sequence

Protein


Download         Length: 324 a.a.        Molecular weight: 36925.97 Da        Isoelectric Point: 8.8537

>NTDB_id=1006722 UXQ45_RS08175 WP_000697221.1 1673590..1674564(-) (comGA) [Staphylococcus aureus strain BSN48-2]
MKILFQEIINKAIEMKASDVHFIPVKNEVSIKFRINDNLEQYEQIGNSIYQKLLVYMKFQAGLDVSTQQVAQSGRYSYHF
NKIYFLRISTLPLSLGQESCVIRIVPQFFQQQKSTYKFNDFKHLMNKKQGLLLFSGPTGSGKSTLMYQMVSYANKALNLN
VISIEDPVEMQIPGIVQINVNDKAGINYVNSFKAILRCDPDVILIGEIRDKDVAKCVIQASLSGHLVLTTLHATDCKGAI
LRLLEMGISVQELIQATNLIINQRLVTTIKQQRQLVCEILSQQQLRYFFSHNHSLPSSFKNLEDKLDDMTRAGVICETTM
DKYI

Nucleotide


Download         Length: 975 bp        

>NTDB_id=1006722 UXQ45_RS08175 WP_000697221.1 1673590..1674564(-) (comGA) [Staphylococcus aureus strain BSN48-2]
TTGAAGATTCTATTTCAAGAAATAATTAATAAAGCGATAGAAATGAAAGCGAGTGATGTACATTTTATTCCAGTTAAAAA
TGAAGTAAGTATTAAATTTAGAATTAATGATAACTTGGAGCAGTATGAACAAATTGGGAATAGCATTTATCAAAAGTTAT
TAGTTTATATGAAGTTTCAAGCTGGGCTTGATGTTTCTACACAGCAAGTCGCACAGAGCGGTCGATATAGTTACCATTTC
AATAAAATATATTTTTTGAGAATATCAACTTTACCATTGTCACTTGGCCAAGAAAGTTGTGTTATCAGAATTGTACCTCA
ATTTTTTCAACAACAGAAATCAACTTATAAATTCAATGATTTTAAACACCTCATGAATAAGAAACAAGGATTACTATTGT
TTAGTGGGCCAACTGGTTCAGGAAAGAGTACATTAATGTATCAAATGGTCTCATACGCGAATAAAGCCTTGAATTTAAAT
GTAATTTCTATAGAGGATCCTGTAGAGATGCAAATTCCTGGTATCGTCCAAATTAATGTGAATGATAAAGCTGGCATTAA
CTATGTAAATTCGTTTAAAGCTATTTTAAGATGTGATCCTGATGTTATTTTAATAGGTGAAATCAGAGATAAAGATGTTG
CCAAGTGTGTTATACAGGCTAGTTTAAGTGGTCACCTTGTTCTGACTACATTGCATGCAACTGATTGTAAAGGTGCTATT
TTAAGGCTATTAGAAATGGGCATTTCTGTACAAGAATTGATACAGGCAACTAACTTAATTATAAACCAACGACTTGTAAC
TACTATTAAGCAACAGCGACAATTAGTATGCGAAATTCTATCTCAGCAACAACTCCGATATTTCTTTTCCCATAATCATT
CATTACCATCATCATTTAAGAACTTAGAAGATAAACTTGATGATATGACAAGAGCAGGTGTCATTTGTGAAACTACAATG
GATAAATACATTTAA

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(7-267)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGA Staphylococcus aureus MW2

99.691

100

0.997
  comGA Staphylococcus aureus N315

99.691

100

0.997

Multiple sequence alignment