Detailed information    

insolico Bioinformatically predicted

Overview

Name   comW   Type   Regulator
Locus tag   FJH52_RS00110 Genome accession   NZ_LR595848
Coordinates   22154..22390 (+) Length   78 a.a.
NCBI ID   WP_000939545.1    Uniprot ID   A0A0H2ZMA7
Organism   Streptococcus pneumoniae strain 4559 isolate 4559     
Function   stabilization and activation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 17154..27390
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FJH52_RS00100 - 20224..21070 (+) 847 Protein_14 IS630 family transposase -
  FJH52_RS00105 - 21105..21889 (-) 785 Protein_15 transposase -
  FJH52_RS00110 comW 22154..22390 (+) 237 WP_000939545.1 sigma(X)-activator ComW Regulator
  FJH52_RS00115 - 22621..23907 (+) 1287 WP_001813655.1 adenylosuccinate synthase -
  FJH52_RS00120 - 24149..25297 (-) 1149 WP_000876732.1 site-specific integrase -
  FJH52_RS00125 - 25469..26383 (-) 915 WP_000690123.1 HIRAN domain-containing protein -
  FJH52_RS00130 - 26395..26778 (-) 384 WP_000136460.1 ImmA/IrrE family metallo-endopeptidase -
  FJH52_RS00135 - 26791..27156 (-) 366 WP_000484469.1 helix-turn-helix domain-containing protein -

Sequence

Protein


Download         Length: 78 a.a.        Molecular weight: 9658.13 Da        Isoelectric Point: 6.7051

>NTDB_id=1006232 FJH52_RS00110 WP_000939545.1 22154..22390(+) (comW) [Streptococcus pneumoniae strain 4559 isolate 4559]
MLQKIYEQMANFYDSIEEEYGPTFGDNFDWEHVHFKFLIYYLVRYGIGCRKDFIVYHYRVAYRLYLEKLVMNRGFISC

Nucleotide


Download         Length: 237 bp        

>NTDB_id=1006232 FJH52_RS00110 WP_000939545.1 22154..22390(+) (comW) [Streptococcus pneumoniae strain 4559 isolate 4559]
ATGTTACAAAAAATTTATGAGCAGATGGCTAATTTCTATGATAGTATTGAAGAAGAGTATGGTCCTACATTTGGTGATAA
TTTTGACTGGGAACATGTTCATTTTAAATTTTTAATTTATTATTTAGTGAGATATGGCATTGGTTGTCGTAAGGATTTTA
TCGTTTACCATTATCGTGTTGCTTATCGTTTGTATCTTGAAAAATTGGTAATGAATCGGGGTTTTATTTCTTGTTGA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0H2ZMA7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comW Streptococcus pneumoniae Rx1

100

100

1
  comW Streptococcus pneumoniae D39

100

100

1
  comW Streptococcus pneumoniae R6

100

100

1
  comW Streptococcus pneumoniae TIGR4

100

100

1
  comW Streptococcus mitis SK321

75.641

100

0.756
  comW Streptococcus mitis NCTC 12261

75.325

98.718

0.744