Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   PCN061_RS17425 Genome accession   NZ_CP006636
Coordinates   3436378..3437010 (+) Length   210 a.a.
NCBI ID   WP_000242755.1    Uniprot ID   A0A1C4FZU4
Organism   Escherichia coli PCN061     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 3431378..3442010
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PCN061_RS17395 (PCN061_3434) yheS 3431547..3433460 (+) 1914 WP_000634789.1 ABC transporter ATP-binding protein -
  PCN061_RS17400 (PCN061_3435) yheT 3433460..3434482 (+) 1023 WP_000057379.1 hydrolase -
  PCN061_RS17405 (PCN061_3436) yheU 3434476..3434694 (+) 219 WP_000907085.1 YheU family protein -
  PCN061_RS17410 (PCN061_3437) prkB 3434748..3435617 (+) 870 WP_001274680.1 phosphoribulokinase -
  PCN061_RS17415 (PCN061_3438) yhfA 3435672..3436076 (-) 405 WP_001148910.1 OsmC family protein -
  PCN061_RS17425 (PCN061_3439) crp 3436378..3437010 (+) 633 WP_000242755.1 cAMP-activated global transcriptional regulator CRP Regulator
  PCN061_RS17430 (PCN061_3440) yhfK 3437061..3439151 (+) 2091 WP_001295162.1 YccS/YhfK family putative transporter -
  PCN061_RS17435 (PCN061_3441) argD 3439218..3440438 (-) 1221 WP_024249933.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  PCN061_RS17440 (PCN061_3442) pabA 3440524..3441087 (-) 564 WP_000601847.1 aminodeoxychorismate synthase component 2 -
  PCN061_RS17445 (PCN061_3443) fic 3441119..3441721 (-) 603 WP_001280624.1 putative adenosine monophosphate-protein transferase Fic -
  PCN061_RS26525 - 3441711..3441806 (-) 96 Protein_3338 YhfG family protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23640.43 Da        Isoelectric Point: 8.2710

>NTDB_id=100604 PCN061_RS17425 WP_000242755.1 3436378..3437010(+) (crp) [Escherichia coli PCN061]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=100604 PCN061_RS17425 WP_000242755.1 3436378..3437010(+) (crp) [Escherichia coli PCN061]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCAGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTCTGTCTGCACAGATGGCGCGTCGTCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTCCTCGACGTGACGGGCCGCATTGCACAGACTCTGCTGAATCTGGCAAAACAACCAGACGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATCGGTCAGATTGTCGGCTGTTCTCGTGAAACCGTGGGACGCAT
TCTGAAGATGCTTGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1C4FZU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.714

100

0.957
  crp Haemophilus influenzae Rd KW20

77.941

97.143

0.757
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467

Multiple sequence alignment