Detailed information NTG1005998

Bioinformatically predicted

Overview

• Name: comEC/celB
• Type: Machinery gene
• Locus tag: FGL22_RS07355
• Genome accession: NZ_LR594048
• Coordinates: 1470313..1472556 (-)
• Length: 747 a.a.
• NCBI ID: WP_014612434.1
• Uniprot ID: -
• Organism: Streptococcus dysgalactiae subsp. equisimilis strain NCTC11556
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1465313..1477556

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FGL22_RS07335 (NCTC11556_01522)	-	1465922..1467142 (+)	1221	WP_003056368.1	DUF3114 domain-containing protein	-
FGL22_RS07340 (NCTC11556_01523)	-	1467263..1468324 (-)	1062	WP_065355251.1	serine hydrolase	-
FGL22_RS07345 (NCTC11556_01524)	sodA	1468491..1469096 (-)	606	WP_014612432.1	superoxide dismutase SodA	-
FGL22_RS07350 (NCTC11556_01525)	holA	1469186..1470232 (-)	1047	WP_014612433.1	DNA polymerase III subunit delta	-
FGL22_RS07355 (NCTC11556_01526)	comEC/celB	1470313..1472556 (-)	2244	WP_014612434.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
FGL22_RS07360 (NCTC11556_01527)	comEA	1472537..1473199 (-)	663	WP_003057999.1	helix-hairpin-helix domain-containing protein	Machinery gene
FGL22_RS07365 (NCTC11556_01528)	-	1473596..1474336 (-)	741	WP_003062277.1	1-acyl-sn-glycerol-3-phosphate acyltransferase	-
FGL22_RS07370 (NCTC11556_01529)	-	1474454..1475230 (+)	777	WP_138128125.1	tRNA1(Val) (adenine(37)-N6)-methyltransferase	-
FGL22_RS07375 (NCTC11556_01530)	-	1475220..1475498 (+)	279	WP_003061674.1	GIY-YIG nuclease family protein	-
FGL22_RS07380 (NCTC11556_01531)	-	1475522..1477522 (-)	2001	WP_014612436.1	potassium transporter Kup	-

Sequence

Protein

• Length: 747 a.a.
• Molecular weight: 85213.73 Da
• Isoelectric Point: 9.2618

>NTDB_id=1005998 FGL22_RS07355 WP_014612434.1 1470313..1472556(-) (comEC/celB) [Streptococcus dysgalactiae subsp. equisimilis strain NCTC11556]
MNYRWTKWSPLPPIQLAFLVMALYYQIYCPSWLTCLLSSCLGMLLLKQFPQKTLCKVVMILALFAAVFVYRKHQLRQQLE
TQPLQVSQVALVPDSIRINGDQLAVIGRHGNHSYQLFYHFKHQTEARFFQKEYRWIVMHAKIVLDKAETSRNFRGFNYQS
FLAYQGIYRIGKVEQVEQLEVVSPKSVGDYLSSLRRQAIVHCQQSFPKPMSHYLTGLLFGYLDKSFGEMTDYYSQLGIIH
LFALSGMQVGFFLTCFRRGLTLLAIPLEWIKWIELPFACLYAALTGYSISVIRSLLQAQLGHLGIKGLDNLACAFLLVLL
WDAHALMTVGGVLTFSYAFMLTIITFEELSGVKKHFVQVITVSLGMLPFLLFYFASFNPMSMVLTELLSYLFDVLILPLL
CLVFCLSPLITLSGCNYLFLFLEKVIQFFGNTLNASLVFGSPTSWHLLILVISFAILYDHRKIRQRVITCGLVIGLTLLS
VKYPLTNEVTFIDIGQGDSILVRDWTGKNLLIDVGGRLSFSSKEQWRQGHQTSNAQKTLIPYLKSRGIHTIDQLLVTHAD
TDHMGDIEVVAKAIRIKEILTSQGSLSQPSFVRRLRGLKCHVRVLAAGDQLPIMGSVLQVLYPWQLGDGKNNDSLVLYGR
LLNRTFLFTGDLEKEGENEIIERYPQLRVDYLKAGHHGSNTSSSAAFLDHIQPKVAFISAGKNNRYQHPHRETLTRLEDR
EISYYRTDIQGAVRLTGWLNWHIETVR

Nucleotide

• Length: 2244 bp

>NTDB_id=1005998 FGL22_RS07355 WP_014612434.1 1470313..1472556(-) (comEC/celB) [Streptococcus dysgalactiae subsp. equisimilis strain NCTC11556]
ATGAACTATCGTTGGACTAAGTGGTCTCCCTTGCCTCCCATTCAACTAGCCTTTTTGGTAATGGCTCTTTATTATCAGAT
CTATTGTCCTAGCTGGTTGACTTGCTTACTTAGCAGTTGTTTAGGAATGTTACTATTGAAGCAGTTTCCTCAGAAGACCC
TCTGTAAGGTTGTTATGATTCTGGCCTTATTTGCTGCTGTCTTTGTTTATCGGAAACATCAGTTGAGACAGCAATTGGAA
ACACAACCTTTACAAGTGTCTCAGGTAGCATTAGTTCCTGATAGTATTCGAATTAATGGAGATCAATTAGCTGTTATTGG
GCGTCACGGTAATCATTCTTATCAGTTGTTTTATCATTTTAAACATCAAACGGAAGCCCGATTTTTCCAAAAAGAGTACC
GTTGGATAGTGATGCATGCCAAAATAGTATTGGACAAGGCTGAGACTTCCCGAAATTTTAGAGGATTTAATTACCAATCT
TTTTTAGCCTATCAGGGAATTTACAGGATAGGAAAAGTGGAACAAGTAGAGCAGCTTGAAGTGGTTTCACCAAAGTCAGT
AGGAGATTATTTATCTTCTTTGAGGCGACAGGCTATTGTCCATTGCCAACAATCCTTTCCAAAGCCCATGTCTCATTATT
TGACGGGACTCCTTTTCGGCTATTTGGATAAGTCCTTTGGTGAGATGACAGATTATTATAGTCAGCTTGGTATCATTCAT
CTTTTTGCCCTATCAGGGATGCAGGTTGGCTTCTTTTTAACCTGTTTTAGAAGAGGTTTGACGCTATTAGCTATTCCTCT
CGAATGGATTAAATGGATAGAGCTTCCCTTTGCCTGTCTATATGCTGCGCTGACAGGTTACAGTATTTCTGTTATTCGAA
GCCTTCTGCAGGCCCAATTAGGTCATCTAGGCATAAAAGGCTTAGATAATCTGGCTTGCGCTTTCTTACTTGTTCTTTTA
TGGGATGCTCATGCTTTGATGACTGTTGGTGGAGTACTAACATTTAGCTATGCGTTTATGTTAACTATTATCACTTTTGA
GGAGTTATCGGGAGTTAAAAAGCATTTCGTCCAGGTCATTACTGTTTCTTTAGGGATGTTACCTTTCTTGCTCTTTTATT
TTGCTAGTTTTAACCCCATGTCAATGGTATTGACAGAGCTTTTGTCTTATCTCTTCGATGTTTTGATTTTGCCTCTTCTT
TGCTTGGTTTTCTGTTTGTCTCCTTTGATAACTCTCTCAGGATGTAATTATCTCTTTCTTTTCTTAGAAAAAGTCATTCA
ATTTTTTGGGAATACCCTCAATGCCTCCCTTGTTTTTGGAAGTCCGACCAGTTGGCACTTGCTTATCCTGGTGATTAGCT
TCGCTATTCTTTATGACCATCGGAAGATACGACAAAGAGTTATCACTTGCGGCTTGGTCATAGGCCTGACGCTTTTATCT
GTTAAATATCCTTTGACCAATGAAGTGACCTTTATCGACATTGGCCAGGGCGATAGTATTTTAGTGAGGGATTGGACAGG
AAAAAATCTCTTAATAGATGTAGGTGGGCGCCTTTCCTTTTCTTCAAAAGAGCAGTGGCGACAGGGGCACCAGACATCGA
ATGCTCAGAAAACCTTAATTCCTTACTTAAAAAGTAGAGGCATTCACACCATTGACCAATTACTAGTGACTCATGCGGAT
ACTGATCATATGGGGGATATAGAGGTGGTTGCCAAAGCTATTCGGATAAAGGAGATTTTGACTAGCCAAGGTAGTTTAAG
CCAGCCAAGCTTTGTTAGGCGGTTAAGGGGTTTAAAATGTCACGTTAGGGTTTTAGCAGCTGGAGACCAATTGCCTATTA
TGGGAAGTGTCTTACAGGTACTCTACCCTTGGCAGTTAGGGGACGGGAAAAATAACGATTCTTTGGTACTTTATGGCAGG
CTCTTAAATCGAACTTTTCTTTTCACAGGTGATTTGGAAAAAGAGGGAGAAAACGAGATCATAGAACGTTATCCTCAACT
AAGAGTAGATTATTTAAAAGCAGGTCACCATGGATCAAATACCTCTTCTAGTGCAGCTTTTTTAGACCATATTCAGCCTA
AAGTGGCCTTTATTTCTGCTGGAAAAAATAACCGTTATCAGCATCCTCACAGAGAAACCCTAACCCGTTTAGAGGATAGG
GAAATTTCTTATTATCGCACGGATATTCAAGGAGCTGTTCGGTTGACAGGATGGCTAAATTGGCATATTGAGACTGTTCG
TTGA

Domains

Predicted by InterProScan.

• Competence protein (Competence) (217-458)

• Metallo-beta-lactamase superfamily (Lactamase_B) (495-701)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC/celB	Streptococcus mitis NCTC 12261	45.845	99.866	0.458
comEC/celB	Streptococcus mitis SK321	45.906	99.732	0.458
comEC/celB	Streptococcus pneumoniae TIGR4	45.321	100	0.454
comEC/celB	Streptococcus pneumoniae Rx1	45.053	100	0.451
comEC/celB	Streptococcus pneumoniae D39	45.053	100	0.451
comEC/celB	Streptococcus pneumoniae R6	45.053	100	0.451
comEC	Lactococcus lactis subsp. cremoris KW2	41.588	99.465	0.414