Detailed information NTG1005789

Bioinformatically predicted

Overview

• Name: comEC/celB
• Type: Machinery gene
• Locus tag: FGL18_RS06965
• Genome accession: NZ_LR594046
• Coordinates: 1443407..1445650 (-)
• Length: 747 a.a.
• NCBI ID: WP_138126021.1
• Uniprot ID: -
• Organism: Streptococcus dysgalactiae strain NCTC6403
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1438407..1450650

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FGL18_RS06945 (NCTC6403_01434)	-	1438698..1440146 (-)	1449	WP_138126013.1	IS1182 family transposase	-
FGL18_RS06950 (NCTC6403_01435)	-	1440357..1441418 (-)	1062	WP_138126015.1	serine hydrolase	-
FGL18_RS06955 (NCTC6403_01436)	sodA	1441585..1442190 (-)	606	WP_138126017.1	superoxide dismutase SodA	-
FGL18_RS06960 (NCTC6403_01437)	holA	1442280..1443326 (-)	1047	WP_138126019.1	DNA polymerase III subunit delta	-
FGL18_RS06965 (NCTC6403_01438)	comEC/celB	1443407..1445650 (-)	2244	WP_138126021.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
FGL18_RS06970 (NCTC6403_01439)	comEA/celA/cilE	1445631..1446293 (-)	663	WP_138126023.1	helix-hairpin-helix domain-containing protein	Machinery gene
FGL18_RS06975 (NCTC6403_01440)	tnpA	1446734..1447207 (-)	474	WP_070001343.1	IS200/IS605 family transposase	-
FGL18_RS06980 (NCTC6403_01441)	-	1447438..1448178 (-)	741	WP_172601443.1	1-acyl-sn-glycerol-3-phosphate acyltransferase	-
FGL18_RS06985 (NCTC6403_01442)	-	1448296..1449072 (+)	777	WP_111717937.1	tRNA1(Val) (adenine(37)-N6)-methyltransferase	-
FGL18_RS06990 (NCTC6403_01443)	-	1449062..1449340 (+)	279	WP_046176932.1	GIY-YIG nuclease family protein	-

Sequence

Protein

• Length: 747 a.a.
• Molecular weight: 85196.74 Da
• Isoelectric Point: 9.3972

>NTDB_id=1005789 FGL18_RS06965 WP_138126021.1 1443407..1445650(-) (comEC/celB) [Streptococcus dysgalactiae strain NCTC6403]
MNYRWTKWSPLPPIQLAFLVMALYYQIYCPSWLTCLLSSCLGMLLLKQFPQKTLCKVVMILALFAAVFVYRKHQLRQQLE
TQPLQVSQVALVPDSIRINGDQLAVIGRHGNHSYQLFYRFKHQTEARFFQKEYRWIVMHAKIVLDKAETSRNFRGFNYQS
FLAYQGIYRIGKVEQVEQLEVVSPKSVGDYLSSLRRQAIVHCQQSFPKPMSHYLTGLLFGYLDKSFGEMTDYYSQLGIIH
LFALSGMQVGFFLTCFRRGLTLLAIPLEWIKWIELPFACLYAALTGYSISVIRSLLQAQLGHLGIKGLDNLACAFLLVLL
WDAHALMTVGGVLTFSYAFMLTVITFEELSGVKKHFVQVVTVSLGMLPFLLFYFASFNPMSMVLTGLLSYLFDVLILPLL
CLVFCLSPLITLSGCNYLFLFLEKVIQFLGNTLNASLVFGSPTSWHLLILVISFAILYDHRQIRQRVITCGLVIGLTLLS
VKYPLTNEVTFIDIGQGDSILVRDWTGKNLLIDVGGRLSFSSKEQWRQGHQTSNAQKTLIPYLKSRGIHTIDQLLVTHAD
TDHMGDIEVVAKAIRIKEILTSQGSLSQPSFVRRLRRLKCHVRVLAAGDQLPIMGSVLQVLYPWQLGNGKNNDSLVLYGR
LLNQTFLFTGDLEKEGENEIIERYPQLRVDYLKAGHHGSNTSSSAAFLDHIQPKVAFISVGKNNRYQHPHRETLTRLEDR
EISYYRTDIQGAVRLTGWLNWHIETVR

Nucleotide

• Length: 2244 bp

>NTDB_id=1005789 FGL18_RS06965 WP_138126021.1 1443407..1445650(-) (comEC/celB) [Streptococcus dysgalactiae strain NCTC6403]
ATGAACTATCGTTGGACTAAGTGGTCTCCCTTGCCTCCCATTCAACTAGCCTTTTTGGTAATGGCTCTTTATTATCAGAT
CTATTGTCCTAGCTGGTTGACTTGCTTACTTAGCAGTTGTTTAGGAATGTTACTATTGAAGCAGTTTCCTCAAAAGACCC
TCTGTAAGGTTGTTATGATTCTGGCCTTATTTGCTGCTGTCTTTGTTTATCGGAAACATCAGTTGAGACAGCAATTGGAA
ACACAACCTTTACAAGTGTCTCAGGTAGCATTGGTTCCGGATAGTATTCGAATTAATGGAGATCAATTAGCTGTTATTGG
GCGTCACGGTAATCATTCTTATCAGTTGTTTTATCGTTTTAAACATCAAACGGAAGCCCGATTTTTCCAAAAAGAGTACC
GTTGGATAGTGATGCATGCCAAAATAGTATTGGACAAGGCTGAGACTTCCCGAAATTTTAGAGGATTTAATTACCAATCT
TTTTTAGCCTATCAGGGAATTTACAGGATAGGAAAAGTGGAACAAGTAGAGCAGCTTGAAGTGGTCTCACCAAAGTCAGT
AGGTGATTATTTATCTTCTTTGAGGCGACAGGCTATTGTCCATTGCCAACAGTCCTTTCCAAAGCCTATGTCTCATTATT
TGACGGGACTCCTTTTCGGCTATTTGGATAAGTCCTTTGGTGAGATGACAGATTATTATAGTCAGCTTGGTATCATTCAT
CTTTTTGCCCTCTCAGGGATGCAGGTTGGCTTCTTTTTAACCTGTTTTAGAAGAGGTTTGACGCTATTAGCTATTCCTCT
CGAATGGATTAAATGGATAGAGCTTCCCTTTGCCTGTCTATATGCTGCGCTGACAGGTTACAGTATTTCTGTTATTCGAA
GCCTTCTGCAGGCCCAATTAGGTCATCTAGGTATAAAAGGCTTAGATAATCTGGCTTGCGCTTTCTTACTTGTTCTTTTA
TGGGATGCTCATGCTTTGATGACTGTTGGTGGAGTACTAACATTTAGCTATGCGTTTATGTTAACTGTTATCACTTTTGA
GGAGTTATCGGGAGTTAAAAAGCATTTCGTTCAGGTCGTCACCGTTTCTTTAGGAATGTTACCTTTCTTGCTCTTTTATT
TTGCTAGTTTTAACCCCATGTCAATGGTATTAACAGGGCTTTTATCTTATCTCTTCGATGTTTTGATTTTGCCTCTTCTT
TGCTTGGTTTTCTGTTTGTCTCCTTTGATAACTCTCTCAGGATGTAATTATCTCTTTCTTTTCTTAGAAAAAGTCATTCA
ATTTCTTGGTAATACCCTCAATGCCTCCCTTGTTTTTGGAAGTCCGACCAGTTGGCACTTGCTTATCCTGGTGATTAGCT
TCGCTATTCTTTATGACCATCGGCAGATACGACAAAGAGTTATCACTTGCGGCTTGGTCATAGGCCTGACGCTTTTATCT
GTTAAATATCCTTTGACCAATGAAGTGACCTTTATCGACATTGGCCAGGGTGATAGTATTTTAGTGAGGGATTGGACAGG
AAAAAATCTCTTAATAGATGTAGGTGGGCGCCTTTCCTTTTCTTCAAAAGAGCAGTGGCGACAGGGGCACCAGACATCGA
ATGCTCAGAAAACCTTAATTCCTTACTTAAAAAGTAGAGGCATTCACACCATTGACCAATTACTAGTGACTCATGCGGAT
ACTGATCATATGGGGGATATAGAGGTGGTTGCCAAAGCTATTCGGATAAAGGAGATTTTGACTAGCCAAGGTAGTTTAAG
CCAGCCGAGCTTTGTTAGGCGGTTAAGGCGTTTAAAATGTCACGTTAGGGTTTTAGCAGCTGGAGACCAATTGCCTATTA
TGGGAAGTGTCTTACAGGTGCTCTATCCTTGGCAGTTAGGGAACGGGAAAAATAATGATTCTCTGGTTCTTTATGGTAGG
CTCCTCAATCAAACTTTTCTATTTACAGGTGATTTGGAAAAAGAGGGGGAAAACGAGATCATAGAACGTTATCCTCAACT
AAGAGTAGATTATTTAAAAGCAGGTCACCATGGATCAAATACCTCTTCTAGTGCAGCTTTTTTAGACCATATTCAGCCTA
AAGTGGCCTTTATTTCTGTTGGAAAAAATAACCGTTATCAGCATCCTCACAGAGAAACCCTAACCCGTTTGGAGGATAGG
GAAATTTCTTATTATCGCACGGATATTCAAGGAGCTGTTCGGTTGACAGGATGGCTAAATTGGCATATTGAGACTGTTCG
TTGA

Domains

Predicted by InterProScan.

• Competence protein (Competence) (217-459)

• Metallo-beta-lactamase superfamily (Lactamase_B) (495-701)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC/celB	Streptococcus mitis SK321	45.772	99.732	0.456
comEC/celB	Streptococcus mitis NCTC 12261	45.71	99.866	0.456
comEC/celB	Streptococcus pneumoniae TIGR4	45.187	100	0.452
comEC/celB	Streptococcus pneumoniae Rx1	44.92	100	0.45
comEC/celB	Streptococcus pneumoniae D39	44.92	100	0.45
comEC/celB	Streptococcus pneumoniae R6	44.92	100	0.45
comEC	Lactococcus lactis subsp. cremoris KW2	41.622	99.063	0.412