Detailed information NTG1005737

Bioinformatically predicted

Overview

• Name: comGF
• Type: Machinery gene
• Locus tag: FGL18_RS00745
• Genome accession: NZ_LR594046
• Coordinates: 120436..120876 (+)
• Length: 146 a.a.
• NCBI ID: WP_138124417.1
• Uniprot ID: -
• Organism: Streptococcus dysgalactiae strain NCTC6403
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 115436..125876

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FGL18_RS00715 (NCTC6403_00145)	-	117069..117434 (+)	366	WP_003055257.1	DUF1033 family protein	-
FGL18_RS00720 (NCTC6403_00146)	comGA	117563..118504 (+)	942	WP_138124405.1	competence type IV pilus ATPase ComGA	Machinery gene
FGL18_RS00725 (NCTC6403_00147)	comGB	118440..119471 (+)	1032	WP_138126921.1	competence type IV pilus assembly protein ComGB	Machinery gene
FGL18_RS00730 (NCTC6403_00148)	comGC	119473..119799 (+)	327	WP_138124408.1	competence type IV pilus major pilin ComGC	Machinery gene
FGL18_RS00735 (NCTC6403_00149)	comGD	119774..120202 (+)	429	WP_256867133.1	competence type IV pilus minor pilin ComGD	Machinery gene
FGL18_RS00740 (NCTC6403_00150)	comGE	120210..120455 (+)	246	WP_242002881.1	competence type IV pilus minor pilin ComGE	Machinery gene
FGL18_RS00745 (NCTC6403_00151)	comGF	120436..120876 (+)	441	WP_138124417.1	competence type IV pilus minor pilin ComGF	Machinery gene
FGL18_RS00750 (NCTC6403_00152)	comGG	120854..121228 (+)	375	WP_138124420.1	competence type IV pilus minor pilin ComGG	-
FGL18_RS00755 (NCTC6403_00153)	comGH	121291..122244 (+)	954	WP_138124423.1	class I SAM-dependent methyltransferase	Machinery gene
FGL18_RS00760 (NCTC6403_00154)	-	122303..123499 (+)	1197	WP_084916957.1	acetate kinase	-
FGL18_RS00765 (NCTC6403_00155)	-	123804..124010 (+)	207	WP_003058508.1	helix-turn-helix transcriptional regulator	-
FGL18_RS00770 (NCTC6403_00156)	-	124113..124793 (+)	681	WP_138124426.1	type II CAAX endopeptidase family protein	-
FGL18_RS00775 (NCTC6403_00157)	-	124811..125248 (+)	438	WP_138124429.1	hypothetical protein	-

Sequence

Protein

• Length: 146 a.a.
• Molecular weight: 16964.49 Da
• Isoelectric Point: 10.5665

>NTDB_id=1005737 FGL18_RS00745 WP_138124417.1 120436..120876(+) (comGF) [Streptococcus dysgalactiae strain NCTC6403]
MKKRTGRVQAFTFLEALIALLVISGSLLVYQGLTKTLLSHSRYLTNHDQDHWLLFSQQLREELSGARFHKVENNKLYIDK
GKKKLVLGQFKSHDFRKSAGNGQGYQPMLFGLSHSHIQAEQSRIRITLHWKSGLERTFYYAFQDQP

Nucleotide

• Length: 441 bp

>NTDB_id=1005737 FGL18_RS00745 WP_138124417.1 120436..120876(+) (comGF) [Streptococcus dysgalactiae strain NCTC6403]
TTGAAAAAAAGGACAGGTAGGGTCCAAGCATTTACTTTTTTAGAGGCTTTAATTGCCTTGCTGGTGATATCAGGTTCTCT
TCTAGTGTATCAAGGATTGACCAAAACACTCCTTAGCCACAGTCGCTACCTTACCAACCATGATCAAGACCATTGGCTTT
TGTTCTCCCAGCAGTTACGAGAAGAGTTAAGTGGAGCGCGATTTCACAAAGTAGAAAACAATAAATTATATATCGACAAA
GGCAAGAAAAAACTAGTTTTAGGACAATTTAAAAGCCATGACTTTCGAAAATCGGCAGGCAATGGACAAGGTTATCAACC
CATGCTGTTTGGCCTGTCTCATAGTCATATACAAGCAGAGCAGTCTCGTATTCGGATTACCCTTCACTGGAAAAGTGGAC
TAGAAAGGACCTTCTACTATGCGTTTCAAGACCAACCTTAA

Domains

Predicted by InterProScan.

• Putative Competence protein ComGF (ComGF) (40-135)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGF	Streptococcus mutans UA159	47.482	95.205	0.452
comGF	Streptococcus mutans UA140	46.763	95.205	0.445
comGF	Lactococcus lactis subsp. cremoris KW2	47.101	94.521	0.445
comGF/cglF	Streptococcus pneumoniae D39	43.796	93.836	0.411
comGF/cglF	Streptococcus mitis NCTC 12261	43.796	93.836	0.411
comGF/cglF	Streptococcus pneumoniae TIGR4	43.796	93.836	0.411
comGF/cglF	Streptococcus pneumoniae R6	43.796	93.836	0.411
comGF/cglF	Streptococcus mitis SK321	43.796	93.836	0.411
comGF/cglF	Streptococcus pneumoniae Rx1	43.796	93.836	0.411