Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEC/celB   Type   Machinery gene
Locus tag   FGK97_RS04120 Genome accession   NZ_LR594037
Coordinates   819420..821648 (+) Length   742 a.a.
NCBI ID   WP_003024728.1    Uniprot ID   -
Organism   Streptococcus anginosus strain NCTC11064     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 814420..826648
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FGK97_RS04105 (NCTC11064_00832) smpB 816640..817107 (+) 468 WP_003024738.1 SsrA-binding protein SmpB -
  FGK97_RS04115 (NCTC11064_00835) comEA/celA/cilE 818732..819436 (+) 705 WP_003024731.1 helix-hairpin-helix domain-containing protein Machinery gene
  FGK97_RS04120 (NCTC11064_00836) comEC/celB 819420..821648 (+) 2229 WP_003024728.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  FGK97_RS04125 (NCTC11064_00837) - 821730..822296 (+) 567 WP_021001633.1 DUF805 domain-containing protein -
  FGK97_RS04130 (NCTC11064_00839) - 822927..823913 (+) 987 WP_003024723.1 Gfo/Idh/MocA family protein -
  FGK97_RS04135 (NCTC11064_00840) - 823935..824588 (+) 654 WP_003024719.1 uracil-DNA glycosylase -
  FGK97_RS04140 (NCTC11064_00841) mutX 824625..825095 (+) 471 WP_003031692.1 NUDIX hydrolase Machinery gene
  FGK97_RS04145 (NCTC11064_00842) - 825108..826385 (+) 1278 WP_003024716.1 dihydroorotase -

Sequence

Protein


Download         Length: 742 a.a.        Molecular weight: 85150.92 Da        Isoelectric Point: 10.0221

>NTDB_id=1005155 FGK97_RS04120 WP_003024728.1 819420..821648(+) (comEC/celB) [Streptococcus anginosus strain NCTC11064]
MSQWIKRFPIKPIYIAFLLVWLYFAIYQSSWLGWLGFIFLVICLFRFYSPKECFMTFMILSCFAGFFFVRREIAEQKTKV
EPSPIRQVAVLPDTIKVNGDSLSFRGKANRQTYQVYYKLKSKEEQLAFQNLSSLVTLTVEGEFEIPEKKRNFAGFDYQSY
LKTQGIYRILKVDTILSSQDRISLHPFEWLSSWRRKALVFIKNHFPNPMSNYMTGLLFGALDTSFDEMSNLYSSLGIIHL
FALSGMQVGFFMEGFRKLLLRLGFTQEMVRKCQYPFSFFYAGMTGFSVSVVRSLVQKLLSQHGITKLDNFALTMMILSLI
MPSFLLSAGGVLSCAYAFVISVIDFESLTSWRKVVVESSVISLGVLPILIFYFGEFQPWSILLTFVFSLIFDTMMLPGLM
FIFLFSPLIKLTQVNFLFEGLENSIRWIASVFGKPIVFGQPSPLLLIVMLLVLAILYDIRQNKKWVIFLSLFLSLLFFIN
KFPLQNEITMVDVGQGDSIFLRDWKGKNVLIDVGGREEIRTKEAWQKRATSSNAEKTLIPYLKSRGVDTIDTLVLTNPNP
DYAGDVLGVAKKFAIKKIYISRSSLSNADFLKKLRETNTFIHVIKQGDKLPIFDHHLQVLSGASKNDHSIVLYGQFFRTR
FLFASDLKEEEEAKLMQHYPKLKTDVLKVGQHGAKSSSSSKFLQQIEPTVALISVGKNNQSKQPSQDTIERFAQLPAKVY
RTDEQGAVKFSGWTNWRLEMVK

Nucleotide


Download         Length: 2229 bp        

>NTDB_id=1005155 FGK97_RS04120 WP_003024728.1 819420..821648(+) (comEC/celB) [Streptococcus anginosus strain NCTC11064]
ATGTCACAGTGGATTAAAAGATTTCCGATTAAGCCGATTTACATTGCTTTTTTGCTCGTCTGGTTGTATTTTGCAATCTA
TCAAAGTAGCTGGTTAGGCTGGTTGGGTTTTATCTTTCTGGTGATTTGTCTTTTTCGCTTTTATTCACCGAAAGAATGTT
TCATGACCTTCATGATCCTCTCTTGTTTTGCTGGTTTTTTCTTTGTTCGTAGGGAAATAGCAGAGCAGAAGACGAAAGTA
GAACCTTCTCCCATAAGACAAGTGGCAGTTCTACCTGACACGATTAAGGTAAATGGTGATTCGCTTTCTTTTCGTGGTAA
AGCTAATAGGCAGACTTATCAAGTTTACTACAAATTGAAATCAAAGGAAGAACAGTTGGCTTTTCAAAATCTCTCTAGTC
TGGTTACATTGACCGTTGAAGGGGAATTTGAAATCCCTGAGAAGAAGCGTAATTTTGCTGGTTTTGATTACCAATCCTAT
TTAAAAACGCAAGGGATTTATCGAATTTTAAAAGTGGATACCATTTTATCGAGCCAAGATAGAATCAGCTTGCACCCTTT
TGAGTGGCTTTCTAGCTGGCGAAGAAAAGCACTGGTATTTATCAAGAACCATTTTCCAAATCCGATGAGTAATTACATGA
CAGGACTCTTATTTGGTGCCTTGGATACATCCTTTGACGAAATGAGCAATCTTTATTCTAGCTTGGGAATTATTCATTTA
TTTGCGCTGTCTGGCATGCAAGTTGGCTTTTTTATGGAGGGATTTCGCAAGTTACTGTTAAGGCTGGGGTTTACACAAGA
AATGGTTCGTAAATGCCAATATCCATTTTCTTTCTTTTATGCGGGAATGACTGGATTTTCAGTATCCGTTGTACGGAGCT
TAGTTCAGAAATTATTATCGCAACATGGTATCACTAAGTTAGATAATTTTGCTTTAACGATGATGATATTGTCCTTGATT
ATGCCGTCCTTTCTTTTGTCGGCAGGAGGAGTTCTCTCCTGTGCTTATGCTTTTGTCATTAGTGTGATAGATTTTGAAAG
TCTGACTTCTTGGCGAAAAGTTGTTGTAGAGAGTAGCGTTATTTCACTTGGTGTTTTACCAATTCTAATCTTTTACTTTG
GTGAATTTCAACCTTGGTCTATTTTGTTGACATTTGTTTTTTCACTAATTTTCGATACAATGATGCTGCCAGGCTTGATG
TTTATTTTTCTTTTTTCGCCTTTGATAAAGCTGACTCAAGTCAATTTTTTATTTGAAGGTTTAGAAAATAGTATTCGTTG
GATAGCAAGTGTCTTTGGTAAACCAATCGTTTTTGGGCAGCCCAGTCCGCTTTTGCTGATTGTCATGTTACTTGTACTAG
CTATTTTGTACGATATTCGGCAAAATAAAAAGTGGGTAATATTTCTTAGTCTGTTTCTTTCATTACTATTTTTCATAAAT
AAATTTCCTTTGCAAAACGAGATCACAATGGTTGATGTTGGACAAGGAGATAGTATTTTTCTGAGAGACTGGAAAGGAAA
AAATGTATTGATTGATGTTGGCGGACGTGAGGAAATTAGAACAAAAGAAGCTTGGCAAAAACGAGCAACTAGCTCAAATG
CAGAGAAAACTTTGATTCCTTACCTAAAAAGTCGTGGCGTAGATACGATTGATACTTTAGTCTTAACAAATCCTAATCCA
GATTATGCAGGAGATGTATTAGGAGTTGCTAAAAAGTTTGCAATAAAGAAAATTTATATTTCCAGAAGTAGTCTAAGCAA
TGCAGATTTCCTAAAGAAATTAAGGGAGACAAATACATTCATTCATGTCATAAAACAAGGTGACAAACTTCCTATTTTTG
ATCATCATTTGCAAGTTCTTTCGGGTGCTAGCAAGAACGACCATTCGATTGTTTTATATGGTCAGTTTTTCCGTACAAGA
TTTTTATTTGCAAGCGATTTGAAAGAAGAAGAGGAAGCAAAGTTGATGCAACATTATCCAAAGTTGAAAACAGATGTCTT
GAAAGTCGGGCAACATGGAGCTAAAAGTTCATCAAGTTCAAAGTTTTTGCAACAAATAGAACCAACGGTTGCGCTCATTT
CTGTTGGGAAAAATAATCAATCTAAGCAACCTAGTCAAGATACAATAGAGCGATTTGCACAATTGCCTGCTAAAGTCTAT
CGGACAGATGAACAAGGGGCAGTTAAATTTTCAGGGTGGACAAACTGGCGATTAGAGATGGTCAAGTAA

Domains

Predicted by InterProScan.

Competence protein (Competence)

(216-461)

Metallo-beta-lactamase superfamily (Lactamase_B)

(492-694)

Domain of unknown function (DUF4131) (DUF4131)

(29-175)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEC/celB Streptococcus mitis SK321

54.752

100

0.551
  comEC/celB Streptococcus mitis NCTC 12261

54.29

100

0.546
  comEC/celB Streptococcus pneumoniae TIGR4

53.815

100

0.542
  comEC/celB Streptococcus pneumoniae Rx1

53.012

100

0.534
  comEC/celB Streptococcus pneumoniae D39

53.012

100

0.534
  comEC/celB Streptococcus pneumoniae R6

53.012

100

0.534
  comEC Lactococcus lactis subsp. cremoris KW2

46.909

100

0.47

Multiple sequence alignment