Detailed information NTG1004899

Bioinformatically predicted

Overview

• Name: comGF
• Type: Machinery gene
• Locus tag: FGL00_RS00750
• Genome accession: NZ_LR594034
• Coordinates: 122542..122982 (+)
• Length: 146 a.a.
• NCBI ID: WP_138098131.1
• Uniprot ID: -
• Organism: Streptococcus dysgalactiae subsp. equisimilis strain NCTC8546
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 117542..127982

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FGL00_RS00720 (NCTC8546_00148)	-	119223..119588 (+)	366	WP_003055257.1	DUF1033 family protein	-
FGL00_RS00725 (NCTC8546_00149)	comGA/cglA	119669..120610 (+)	942	WP_138098129.1	competence type IV pilus ATPase ComGA	Machinery gene
FGL00_RS00730 (NCTC8546_00150)	comGB	120546..121577 (+)	1032	WP_138098784.1	competence type IV pilus assembly protein ComGB	Machinery gene
FGL00_RS00735 (NCTC8546_00151)	comGC	121579..121905 (+)	327	WP_003055259.1	competence type IV pilus major pilin ComGC	Machinery gene
FGL00_RS00740 (NCTC8546_00152)	comGD	121880..122308 (+)	429	WP_014611932.1	competence type IV pilus minor pilin ComGD	Machinery gene
FGL00_RS00745 (NCTC8546_00153)	comGE	122316..122561 (+)	246	WP_003058569.1	competence type IV pilus minor pilin ComGE	Machinery gene
FGL00_RS00750 (NCTC8546_00154)	comGF	122542..122982 (+)	441	WP_138098131.1	competence type IV pilus minor pilin ComGF	Machinery gene
FGL00_RS00755 (NCTC8546_00155)	comGG	123005..123334 (+)	330	WP_003058539.1	competence type IV pilus minor pilin ComGG	-
FGL00_RS00760 (NCTC8546_00156)	comGH	123397..124350 (+)	954	WP_003060701.1	class I SAM-dependent methyltransferase	Machinery gene
FGL00_RS00765 (NCTC8546_00157)	-	124409..125605 (+)	1197	WP_138098133.1	acetate kinase	-
FGL00_RS00770 (NCTC8546_00158)	-	125911..126117 (+)	207	WP_003058508.1	helix-turn-helix transcriptional regulator	-
FGL00_RS00775 (NCTC8546_00159)	-	126220..126900 (+)	681	WP_003060329.1	type II CAAX endopeptidase family protein	-
FGL00_RS00780 (NCTC8546_00160)	-	126918..127355 (+)	438	WP_012766452.1	hypothetical protein	-

Sequence

Protein

• Length: 146 a.a.
• Molecular weight: 16968.61 Da
• Isoelectric Point: 10.7829

>NTDB_id=1004899 FGL00_RS00750 WP_138098131.1 122542..122982(+) (comGF) [Streptococcus dysgalactiae subsp. equisimilis strain NCTC8546]
MKKRTGRVQAFTFLEALIALLVISGSLLVYQGLTKTLLSHSRYLTKNDQDHWILFSQQLREELSGARFHKVENNKLYIEK
GKKKLVLGQFKSHDFRKSAGNGQGYQPMLFGLSHSHIQAEQSRIRITLHWKSGLKRTFYYAFQDQP

Nucleotide

• Length: 441 bp

>NTDB_id=1004899 FGL00_RS00750 WP_138098131.1 122542..122982(+) (comGF) [Streptococcus dysgalactiae subsp. equisimilis strain NCTC8546]
TTGAAAAAAAGGACAGGTAGGGTCCAAGCATTTACTTTTTTAGAGGCTTTAATTGCCTTACTGGTGATATCAGGTTCTCT
TCTAGTGTATCAAGGATTGACCAAAACACTCCTTAGCCACAGTCGCTACCTTACCAAAAATGATCAAGACCATTGGATTT
TGTTCTCCCAGCAGTTACGAGAAGAGTTAAGTGGAGCGCGATTTCACAAAGTAGAGAACAATAAATTATATATCGAAAAA
GGCAAGAAAAAACTAGTTTTAGGACAATTTAAAAGCCATGACTTTCGAAAATCGGCAGGCAATGGACAAGGTTATCAACC
CATGCTGTTTGGCCTGTCTCATAGTCATATACAAGCAGAGCAGTCTCGTATTCGTATTACCCTTCACTGGAAAAGTGGAC
TAAAAAGGACCTTCTACTATGCGTTTCAAGACCAACCTTAA

Domains

Predicted by InterProScan.

• Putative Competence protein ComGF (ComGF) (40-135)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGF	Streptococcus mutans UA159	47.482	95.205	0.452
comGF	Streptococcus mutans UA140	46.763	95.205	0.445
comGF	Lactococcus lactis subsp. cremoris KW2	45.652	94.521	0.432
comGF/cglF	Streptococcus pneumoniae D39	42.336	93.836	0.397
comGF/cglF	Streptococcus mitis NCTC 12261	42.336	93.836	0.397
comGF/cglF	Streptococcus pneumoniae TIGR4	42.336	93.836	0.397
comGF/cglF	Streptococcus pneumoniae R6	42.336	93.836	0.397
comGF/cglF	Streptococcus mitis SK321	42.336	93.836	0.397
comGF/cglF	Streptococcus pneumoniae Rx1	42.336	93.836	0.397