Detailed information NTG1004482

Bioinformatically predicted

Overview

• Name: cclA/cilC
• Type: Machinery gene
• Locus tag: E0F34_RS08300
• Genome accession: NZ_LR536843
• Coordinates: 1525304..1525963 (+)
• Length: 219 a.a.
• NCBI ID: WP_000565023.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain GPSC55 substr. ST3774 isolate b04a6400-1f66-11e7-b93e-3c4a9275d6c8
• Function: processing and translocation of ComGC; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1520304..1530963

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
E0F34_RS08270 (SAMEA104035599_01569)	-	1520334..1521287 (+)	954	WP_001155321.1	IS30-like element ISSpn8 family transposase	-
E0F34_RS08280 (SAMEA104035599_01570)	-	1521692..1522168 (-)	477	WP_061650030.1	hypothetical protein	-
E0F34_RS08285 (SAMEA104035599_01571)	-	1522631..1522900 (-)	270	WP_130897118.1	hypothetical protein	-
E0F34_RS08290 (SAMEA104035599_01573)	-	1523404..1524366 (-)	963	WP_054382625.1	protein rep	-
E0F34_RS08295 (SAMEA104035599_01574)	-	1524788..1525234 (-)	447	WP_000155407.1	GNAT family N-acetyltransferase	-
E0F34_RS08300 (SAMEA104035599_01575)	cclA/cilC	1525304..1525963 (+)	660	WP_000565023.1	prepilin peptidase	Machinery gene
E0F34_RS08305 (SAMEA104035599_01576)	trpA	1525935..1526711 (-)	777	WP_001127001.1	tryptophan synthase subunit alpha	-
E0F34_RS08310 (SAMEA104035599_01577)	trpB	1526704..1527927 (-)	1224	WP_000331265.1	tryptophan synthase subunit beta	-
E0F34_RS08315 (SAMEA104035599_01578)	-	1527905..1528504 (-)	600	WP_061649863.1	phosphoribosylanthranilate isomerase	-
E0F34_RS08320 (SAMEA104035599_01579)	trpC	1528491..1529258 (-)	768	WP_000076548.1	indole-3-glycerol phosphate synthase TrpC	-
E0F34_RS08325 (SAMEA104035599_01580)	trpD	1529255..1530259 (-)	1005	WP_000658684.1	anthranilate phosphoribosyltransferase	-
E0F34_RS08330 (SAMEA104035599_01581)	-	1530270..1530836 (-)	567	WP_000601921.1	aminodeoxychorismate/anthranilate synthase component II	-

Sequence

Protein

• Length: 219 a.a.
• Molecular weight: 24921.13 Da
• Isoelectric Point: 8.2409

>NTDB_id=1004482 E0F34_RS08300 WP_000565023.1 1525304..1525963(+) (cclA/cilC) [Streptococcus pneumoniae strain GPSC55 substr. ST3774 isolate b04a6400-1f66-11e7-b93e-3c4a9275d6c8]
MIDFYFFLVGSILASFLGLVIDRFPEQSIISSASHCDSCQTRLRPLDLIPILSQVFNRFRCRYCKVRYPVWYALFELVLG
LLFLLYSWKLLSLGQVVLITAGLTLGIYDFHHQEYPLLVWMTFHLILIASSGWNLVMVSFLILGILAHFIDIRMGAGDFL
FLASCALVFSVTELLILIQFASATGILAFLLQKKKERLPFVPFLLLATCLIIFGKLLLV

Nucleotide

• Length: 660 bp

>NTDB_id=1004482 E0F34_RS08300 WP_000565023.1 1525304..1525963(+) (cclA/cilC) [Streptococcus pneumoniae strain GPSC55 substr. ST3774 isolate b04a6400-1f66-11e7-b93e-3c4a9275d6c8]
ATGATTGATTTTTATTTTTTTCTCGTCGGGAGCATTCTCGCTTCCTTTCTTGGTTTGGTCATTGACCGTTTTCCAGAGCA
ATCCATTATCAGTTCAGCCAGTCACTGCGATTCCTGTCAGACTCGCTTGCGTCCCTTAGATTTGATTCCGATTCTCTCAC
AGGTCTTCAATCGCTTTCGCTGTCGCTACTGCAAAGTTCGCTATCCTGTCTGGTATGCCCTCTTTGAATTAGTCTTAGGA
CTCCTCTTTCTGCTTTACTCTTGGAAATTGCTTTCCTTGGGGCAAGTCGTCCTAATCACCGCTGGTTTGACCTTGGGTAT
CTACGACTTTCACCATCAGGAATATCCCTTACTGGTCTGGATGACTTTCCACCTAATCCTAATAGCTTCCTCTGGCTGGA
ATCTGGTCATGGTCTCCTTCCTCATACTTGGAATTTTGGCTCATTTTATCGATATCCGCATGGGCGCAGGGGATTTCCTC
TTTTTAGCTTCTTGTGCTCTCGTCTTTAGCGTAACGGAGTTACTGATCTTGATTCAGTTTGCTTCTGCGACGGGTATCCT
GGCCTTTCTCCTGCAAAAGAAAAAGGAAAGACTTCCTTTCGTGCCTTTCCTCTTACTTGCTACTTGTTTGATTATTTTTG
GTAAGCTACTGCTTGTTTGA

Domains

Predicted by InterProScan.

• Bacterial Peptidase A24 N-terminal domain (A24_N_bact) (8-89)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
cclA/cilC	Streptococcus pneumoniae TIGR4	97.717	100	0.977
cclA/cilC	Streptococcus pneumoniae Rx1	96.347	100	0.963
cclA/cilC	Streptococcus pneumoniae D39	96.347	100	0.963
cclA/cilC	Streptococcus pneumoniae R6	96.347	100	0.963
cclA/cilC	Streptococcus mitis SK321	92.237	100	0.922
cclA/cilC	Streptococcus mitis NCTC 12261	86.301	100	0.863