Detailed information NTG1001575

Bioinformatically predicted

Overview

• Name: cclA/cilC
• Type: Machinery gene
• Locus tag: EL130_RS04485
• Genome accession: NZ_LR134320
• Coordinates: 872531..873187 (-)
• Length: 218 a.a.
• NCBI ID: WP_002266318.1
• Uniprot ID: Q9KWH4
• Organism: Streptococcus mutans strain NCTC10832
• Function: processing and translocation of ComGC; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 867531..878187

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EL130_RS04460 (NCTC10832_00851)	trpD	867965..868972 (+)	1008	WP_002264435.1	anthranilate phosphoribosyltransferase	-
EL130_RS04465 (NCTC10832_00852)	trpC	868965..869732 (+)	768	WP_002296123.1	indole-3-glycerol phosphate synthase TrpC	-
EL130_RS04470 (NCTC10832_00853)	-	869719..870300 (+)	582	WP_002272562.1	phosphoribosylanthranilate isomerase	-
EL130_RS04475 (NCTC10832_00854)	trpB	870297..871508 (+)	1212	WP_002283412.1	tryptophan synthase subunit beta	-
EL130_RS04480 (NCTC10832_00855)	trpA	871512..872294 (+)	783	WP_002276867.1	tryptophan synthase subunit alpha	-
EL130_RS04485 (NCTC10832_00856)	cclA/cilC	872531..873187 (-)	657	WP_002266318.1	prepilin peptidase	Machinery gene
EL130_RS04490 (NCTC10832_00857)	dpr	873288..873815 (+)	528	WP_002266317.1	DNA starvation/stationary phase protection protein	-
EL130_RS04495 (NCTC10832_00858)	-	874022..874228 (+)	207	WP_002262060.1	YqgQ family protein	-
EL130_RS04500 (NCTC10832_00859)	-	874221..875192 (+)	972	WP_002268147.1	ROK family glucokinase	-
EL130_RS04505 (NCTC10832_00860)	-	875202..875591 (+)	390	WP_002262062.1	rhodanese-like domain-containing protein	-
EL130_RS04515 (NCTC10832_00861)	typA	875825..877669 (+)	1845	WP_002262063.1	translational GTPase TypA	-
EL130_RS04520 (NCTC10832_00862)	-	877698..877952 (+)	255	WP_002262064.1	DUF3165 family protein	-

Sequence

Protein

• Length: 218 a.a.
• Molecular weight: 24893.10 Da
• Isoelectric Point: 8.5763

>NTDB_id=1001575 EL130_RS04485 WP_002266318.1 872531..873187(-) (cclA/cilC) [Streptococcus mutans strain NCTC10832]
MKLILFFMLGASLGSFFGLVVDRYPQKSIIFPRSHCNKCYNCLTMRDLIPIFSRIINKNSCRFCGYPIPLRYSLVELLCG
LISTGFALDLLTTSQVCLLFMGVLLSLYDLQDQSYPLTLWIGFTFLLMFIYPLNLISLILFLFGIFAALKNINIGSGDFF
YLATLALSLNLQQIIWIIQIASLLGILYSLLFQKHKEPFAFVPFLFLGHLIIIFSHLI

Nucleotide

• Length: 657 bp

>NTDB_id=1001575 EL130_RS04485 WP_002266318.1 872531..873187(-) (cclA/cilC) [Streptococcus mutans strain NCTC10832]
ATGAAACTTATTTTATTTTTTATGTTGGGAGCTTCTCTTGGCTCTTTCTTTGGCTTAGTTGTTGATCGTTACCCTCAGAA
ATCTATTATATTTCCTAGAAGCCATTGCAATAAGTGTTATAACTGCTTAACCATGAGGGATCTTATCCCAATATTTTCAC
GAATCATCAACAAAAATTCTTGTCGCTTTTGCGGTTACCCTATTCCATTGCGTTATTCCTTGGTAGAATTACTCTGCGGA
CTGATTAGCACAGGTTTTGCTCTTGATTTATTAACCACTTCACAAGTATGTTTGCTCTTCATGGGAGTTCTTTTATCTCT
TTATGATTTACAAGATCAGTCTTATCCTTTGACACTGTGGATAGGCTTTACTTTTCTCTTAATGTTTATCTATCCTCTTA
ACCTAATTAGCTTAATTCTTTTTCTATTTGGTATTTTTGCTGCCCTCAAAAATATTAATATCGGAAGCGGTGATTTCTTC
TATCTGGCTACTTTGGCACTTTCTCTTAATCTTCAGCAAATTATTTGGATTATTCAGATTGCCAGTTTATTAGGAATTCT
TTACAGCCTGCTTTTTCAAAAGCACAAAGAACCTTTTGCTTTTGTTCCTTTCTTATTCTTGGGTCACCTCATTATCATTT
TCTCTCACTTGATTTAA

Domains

Predicted by InterProScan.

• Bacterial Peptidase A24 N-terminal domain (A24_N_bact) (9-87)

3D structure

• AlphaFold DB: Q9KWH4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
cclA/cilC	Streptococcus mitis SK321	42.791	98.624	0.422
cclA/cilC	Streptococcus pneumoniae Rx1	42.254	97.706	0.413
cclA/cilC	Streptococcus pneumoniae D39	42.254	97.706	0.413
cclA/cilC	Streptococcus pneumoniae R6	42.254	97.706	0.413
cclA/cilC	Streptococcus mitis NCTC 12261	41.86	98.624	0.413
cclA/cilC	Streptococcus pneumoniae TIGR4	41.315	97.706	0.404