Detailed information NTG1001209

Bioinformatically predicted

Overview

• Name: ruvB
• Type: Machinery gene
• Locus tag: EL107_RS07520
• Genome accession: NZ_LR134314
• Coordinates: 1473907..1474905 (-)
• Length: 332 a.a.
• NCBI ID: WP_002986679.1
• Uniprot ID: A2RC05
• Organism: Streptococcus pyogenes strain NCTC8302
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 1468907..1479905

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EL107_RS07505 (NCTC8302_01487)	-	1471136..1472911 (-)	1776	WP_011184071.1	acyltransferase family protein	-
EL107_RS07510 (NCTC8302_01488)	-	1472908..1473309 (-)	402	WP_002986671.1	MORN repeat-containing protein	-
EL107_RS07515 (NCTC8302_01489)	-	1473332..1473769 (-)	438	WP_002994668.1	low molecular weight protein-tyrosine-phosphatase	-
EL107_RS07520 (NCTC8302_01490)	ruvB	1473907..1474905 (-)	999	WP_002986679.1	Holliday junction branch migration DNA helicase RuvB	Machinery gene
EL107_RS09755 (NCTC8302_01491)	comS	1474952..1475047 (-)	96	WP_198462994.1	quorum-sensing system DWW-type pheromone	Regulator
EL107_RS07525 (NCTC8302_01492)	comR	1475131..1476042 (-)	912	WP_002986681.1	transcriptional regulator Rgg4/ComR	Regulator
EL107_RS07530 (NCTC8302_01493)	purB	1476173..1477465 (-)	1293	WP_011184069.1	adenylosuccinate lyase	-
EL107_RS07540 (NCTC8302_01494)	-	1477681..1479021 (-)	1341	WP_011184068.1	hypothetical protein	-

Sequence

Protein

• Length: 332 a.a.
• Molecular weight: 37565.11 Da
• Isoelectric Point: 5.3005

>NTDB_id=1001209 EL107_RS07520 WP_002986679.1 1473907..1474905(-) (ruvB) [Streptococcus pyogenes strain NCTC8302]
MARILDNNVMGNEEFSDRTLRPQYLHEYIGQDKVKEQFAIFIEAAKRRDESLDHVLLFGPPGLGKTTMAFVIANELGVNL
KQTSGPAVEKAGDLVAILNELEPGDILFIDEIHRMPMSVEEVLYSAMEDFYIDIMIGAGDTSRSIHLDLPPFTLIGATTR
AGMLSNPLRARFGITGHMEYYQEKDLTEIVERTATIFEIKIDHEAARKLACRSRGTPRIANRLLKRVRDYAQIIGDGIIT
AQITDRALTMLDVDREGLDYIDQKILRTMIEMYQGGPVGLGTLSVNIAEERNTVEEMYEPYLIQKGFLMRTRTGRVATQK
AYRHLGYPYQNT

Nucleotide

• Length: 999 bp

>NTDB_id=1001209 EL107_RS07520 WP_002986679.1 1473907..1474905(-) (ruvB) [Streptococcus pyogenes strain NCTC8302]
ATGGCTAGAATTTTAGACAATAATGTAATGGGAAATGAGGAGTTTTCGGATCGGACTCTTCGCCCTCAATATCTACACGA
ATATATTGGACAAGATAAAGTTAAGGAACAATTCGCTATTTTTATAGAAGCAGCTAAAAGACGTGACGAATCTTTAGACC
ATGTTTTATTATTTGGACCTCCAGGACTGGGAAAAACAACAATGGCATTTGTGATTGCCAATGAATTGGGAGTTAATTTA
AAGCAAACTTCAGGTCCTGCCGTTGAGAAAGCTGGAGATTTGGTAGCTATTTTAAATGAATTAGAACCAGGGGATATTTT
GTTTATTGATGAAATTCACCGCATGCCAATGTCTGTCGAGGAAGTACTATATAGTGCTATGGAAGACTTCTATATTGATA
TTATGATTGGCGCTGGGGATACTAGTCGTAGTATTCATTTGGATCTGCCTCCATTTACATTGATTGGTGCTACTACACGT
GCAGGCATGTTATCTAATCCCCTCAGAGCTCGTTTTGGTATCACTGGTCACATGGAATACTATCAAGAAAAGGATTTGAC
AGAGATTGTGGAGCGTACAGCTACTATTTTTGAAATAAAAATAGACCATGAAGCTGCACGGAAATTAGCTTGTCGCAGTA
GAGGAACGCCCCGCATTGCTAATCGATTACTAAAACGAGTGCGTGACTATGCTCAAATTATTGGTGATGGCATCATAACG
GCTCAAATAACTGATAGAGCTTTGACTATGTTAGATGTTGACCGCGAAGGTCTCGATTACATTGATCAGAAAATTTTACG
AACGATGATTGAGATGTATCAGGGAGGACCAGTTGGTTTGGGGACATTATCTGTGAATATTGCCGAGGAGCGTAATACAG
TTGAAGAGATGTATGAACCCTACTTAATTCAAAAAGGCTTTCTCATGCGAACACGAACAGGTCGTGTAGCGACGCAAAAG
GCTTATCGTCATCTTGGCTATCCCTATCAAAACACTTAA

Domains

Predicted by InterProScan.

• RuvB C-terminal winged helix domain (WHD_RuvB) (256-325)

• RuvB AAA lid domain (AAA_lid_4) (181-254)

• Holliday junction DNA helicase RuvB P-loop domain (RuvB_N) (20-178)

3D structure

• AlphaFold DB: A2RC05

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ruvB	Streptococcus pneumoniae R6	84.848	99.398	0.843
ruvB	Streptococcus pneumoniae D39	84.848	99.398	0.843
ruvB	Streptococcus pneumoniae TIGR4	84.545	99.398	0.84
ruvB	Bacillus subtilis subsp. subtilis str. 168	58.824	97.289	0.572
ruvB	Helicobacter pylori 26695	48.936	99.096	0.485
ruvB	Synechocystis sp. PCC 6803	50.16	94.277	0.473