Detailed information    

insolico Bioinformatically predicted

Overview

Name   comD/blpH   Type   Regulator
Locus tag   EL070_RS10130 Genome accession   NZ_LR134284
Coordinates   187801..188190 (+) Length   129 a.a.
NCBI ID   WP_231873482.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain NCTC8232     
Function   phosphorylation of ComE; regulation of comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 182801..193190
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL070_RS01075 (NCTC8232_00209) - 183492..184724 (-) 1233 WP_011184134.1 transglutaminase domain-containing protein -
  EL070_RS01085 (NCTC8232_00211) - 185199..185576 (-) 378 WP_023612231.1 hypothetical protein -
  EL070_RS01090 (NCTC8232_00212) - 185769..186101 (+) 333 WP_023612241.1 LytR/AlgR family response regulator transcription factor -
  EL070_RS01095 (NCTC8232_00213) comE/blpR 186110..186847 (+) 738 WP_023612237.1 response regulator transcription factor Regulator
  EL070_RS10130 (NCTC8232_00215) comD/blpH 187801..188190 (+) 390 WP_231873482.1 GHKL domain-containing protein Regulator
  EL070_RS09995 (NCTC8232_00216) - 188261..188404 (-) 144 WP_023612234.1 hypothetical protein -
  EL070_RS10315 - 189178..189309 (+) 132 WP_023612236.1 hypothetical protein -
  EL070_RS01105 (NCTC8232_00218) comA 189888..192038 (+) 2151 WP_023612228.1 peptide cleavage/export ABC transporter ComA Regulator

Sequence

Protein


Download         Length: 129 a.a.        Molecular weight: 14933.96 Da        Isoelectric Point: 4.5438

>NTDB_id=1000080 EL070_RS10130 WP_231873482.1 187801..188190(+) (comD/blpH) [Streptococcus pyogenes strain NCTC8232]
MIEGQQKGIEISVEIDEMIDTPDMELIDFITLLSILLDNAIEEAERCQDARIVFAYFQDRQRKILFIENTTLEKKVNIDA
IYQYGYSSKGENRGIGLANVKAIVNRYSKISLSTNSHYHKFTQELSFFE

Nucleotide


Download         Length: 390 bp        

>NTDB_id=1000080 EL070_RS10130 WP_231873482.1 187801..188190(+) (comD/blpH) [Streptococcus pyogenes strain NCTC8232]
ATGATAGAAGGTCAACAAAAAGGAATAGAAATATCTGTTGAAATTGATGAAATGATTGATACTCCTGATATGGAGTTAAT
CGATTTTATTACCTTACTTTCTATTTTGTTAGATAATGCTATAGAGGAAGCAGAAAGATGCCAAGATGCTCGTATTGTAT
TTGCTTATTTTCAAGACCGACAGCGAAAGATTCTATTTATTGAAAATACAACGCTTGAGAAGAAGGTTAATATTGATGCC
ATCTATCAATATGGTTATTCTAGCAAGGGAGAAAATCGTGGAATTGGTTTGGCTAATGTAAAAGCAATTGTTAATAGGTA
TTCTAAAATTAGTTTATCAACTAATAGTCATTATCATAAGTTTACTCAAGAATTATCATTTTTTGAATAA

Domains

Predicted by InterProScan.

GHKL domain (HATPase_c_5)

(24-125)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comD/blpH Streptococcus mutans UA159

45.6

96.899

0.442
  comD/comD3 Streptococcus equinus JB1

41.406

99.225

0.411
  comD/comD2 Streptococcus equinus JB1

39.062

99.225

0.388
  comD/comD1 Streptococcus equinus JB1

39.516

96.124

0.38

Multiple sequence alignment