Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | I | Classification (family/domain) | ralRA/- |
Location | 1517725..1518096 | Replicon | chromosome |
Accession | NZ_CP014272 | ||
Organism | Escherichia coli K-12 strain K-12 C3026 |
Toxin (Protein)
Gene name | ralR | Uniprot ID | F4VC37 |
Locus tag | C3026_RS07870 | Protein ID | WP_001317028.1 |
Coordinates | 1517902..1518096 (-) | Length | 65 a.a. |
Antitoxin (RNA)
Gene name | ralA | ||
Locus tag | - | ||
Coordinates | 1517725..1517903 (+) |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
C3026_RS07845 | 1513680..1515053 | + | 1374 | WP_000123737.1 | ATP-dependent RNA helicase DbpA | - |
C3026_RS07850 | 1515182..1516117 | - | 936 | WP_001157406.1 | tRNA 2-thiocytidine(32) synthetase TtcA | - |
C3026_RS25695 | 1516169..1517404 | - | 1236 | WP_000040852.1 | site-specific integrase | - |
C3026_RS07860 | 1517406..1517621 | - | 216 | WP_000079604.1 | excisionase XisR | - |
C3026_RS07865 | 1517700..1517909 | - | 210 | WP_000276809.1 | double-strand break reduction protein RcbA | - |
- | 1517725..1517903 | + | 179 | NuclAT_0 | - | Antitoxin |
- | 1517725..1517903 | + | 179 | NuclAT_0 | - | Antitoxin |
- | 1517725..1517903 | + | 179 | NuclAT_0 | - | Antitoxin |
- | 1517725..1517903 | + | 179 | NuclAT_0 | - | Antitoxin |
C3026_RS07870 | 1517902..1518096 | - | 195 | WP_001317028.1 | type I toxin-antitoxin system endodeoxyribonuclease toxin RalR | Toxin |
C3026_RS07875 | 1518153..1518962 | - | 810 | WP_000166319.1 | recombination protein RecT | - |
C3026_RS07880 | 1518955..1521555 | - | 2601 | WP_000105143.1 | exodeoxyribonuclease VIII | - |
C3026_RS07885 | 1521657..1521932 | - | 276 | WP_000632297.1 | protein RacC | - |
C3026_RS07890 | 1522007..1522177 | - | 171 | WP_001352098.1 | conserved protein, Rac prophage | - |
C3026_RS07895 | 1522177..1522398 | - | 222 | WP_000560225.1 | killing protein KilR | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
inside | Prophage | - | - | 1515182..1537843 | 22661 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 65 a.a. Molecular weight: 7018.89 Da Isoelectric Point: 8.9538
>T60573 WP_001317028.1 NZ_CP014272:c1518096-1517902 [Escherichia coli K-12]
MRYDNVKPCPFCGCPSVTVKAISGYYRAKCNGCESRTGYGGSEKEALERWNKRTTGNNNGGVHV
MRYDNVKPCPFCGCPSVTVKAISGYYRAKCNGCESRTGYGGSEKEALERWNKRTTGNNNGGVHV
Download Length: 195 bp
>T60573 NZ_CP014272:c1518096-1517902 [Escherichia coli K-12]
ATGAGATATGACAATGTTAAACCATGTCCATTTTGTGGTTGTCCATCAGTAACGGTGAAAGCCATTTCAGGATATTACCG
AGCGAAGTGTAACGGATGCGAATCCCGAACCGGTTATGGTGGAAGTGAAAAAGAAGCACTCGAAAGATGGAATAAACGAA
CCACTGGAAATAATAATGGAGGTGTTCATGTATAA
ATGAGATATGACAATGTTAAACCATGTCCATTTTGTGGTTGTCCATCAGTAACGGTGAAAGCCATTTCAGGATATTACCG
AGCGAAGTGTAACGGATGCGAATCCCGAACCGGTTATGGTGGAAGTGAAAAAGAAGCACTCGAAAGATGGAATAAACGAA
CCACTGGAAATAATAATGGAGGTGTTCATGTATAA
Antitoxin
Download Length: 179 bp
>AT60573 NZ_CP014272:1517725-1517903 [Escherichia coli K-12]
GAGGACTGAAGTTTCTCGCAATTAAAATTTATCAGTTTTACTTTCTGCTCTCTGGAAACGCCTGCTTCTTTTTTACCTGA
GAGCATTTTTTCGCATTCTGATTTCGTTAGTTTAGATTTTGAATATCTTGTCCAGTTAGTAGGAGTGCCACCTTCCTTTT
CAATAGTGGCGGTAATTTT
GAGGACTGAAGTTTCTCGCAATTAAAATTTATCAGTTTTACTTTCTGCTCTCTGGAAACGCCTGCTTCTTTTTTACCTGA
GAGCATTTTTTCGCATTCTGATTTCGTTAGTTTAGATTTTGAATATCTTGTCCAGTTAGTAGGAGTGCCACCTTCCTTTT
CAATAGTGGCGGTAATTTT
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|