Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-Phd
Location 843491..844038 Replicon chromosome
Accession NZ_CP013013
Organism Vibrio cholerae strain Env-390

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag AP033_RS03825 Protein ID WP_000229325.1
Coordinates 843491..843793 (-) Length 101 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag AP033_RS03830 Protein ID WP_070961997.1
Coordinates 843781..844038 (-) Length 86 a.a.

Genomic Context

AP033_RS03845AP033_RS03850AP033_RS03795AP033_RS03800AP033_RS03805AP033_RS20035AP033_RS03815AP033_RS03820AP033_RS19075AP033_RS19080AP033_RS19085AP033_RS03825AP033_RS03830AP033_RS03835AP033_RS03840AP033_RS03855AP033_RS03860AP033_RS03865AP033_RS03870
Location: 846118..846390 (273 bp)
Type: Others
Protein ID: WP_000246253.1
Location: 846387..846884 (498 bp)
Type: Others
Protein ID: WP_000982260.1
Location: 839380..839682 (303 bp)
Type: Others
Protein ID: WP_000229317.1
Location: 839670..839927 (258 bp)
Type: Others
Protein ID: WP_000861987.1
Location: 840129..840662 (534 bp)
Type: Others
Protein ID: WP_000118351.1
Location: 840659..841084 (426 bp)
Type: Others
Protein ID: WP_001882332.1
Location: 841151..841522 (372 bp)
Type: Others
Protein ID: WP_001164080.1
Location: 841770..842030 (261 bp)
Type: Others
Protein ID: WP_032468027.1
Location: 842048..842208 (161 bp)
Type: Others
Protein ID: Protein_742
Location: 842442..842666 (225 bp)
Type: Others
Protein ID: WP_161571222.1
Location: 842996..843106 (111 bp)
Type: Others
Protein ID: WP_076025930.1
Location: 843491..843793 (303 bp)
Type: Toxin
Protein ID: WP_000229325.1
Location: 843781..844038 (258 bp)
Type: Antitoxin
Protein ID: WP_070961997.1
Location: 844511..845491 (981 bp)
Type: Others
Protein ID: WP_000019368.1
Location: 845561..845887 (327 bp)
Type: Others
Protein ID: Protein_748
Location: 847087..847239 (153 bp)
Type: Others
Protein ID: WP_001884520.1
Location: 847561..848016 (456 bp)
Type: Others
Protein ID: WP_001245327.1
Location: 848144..848431 (288 bp)
Type: Others
Protein ID: WP_000221354.1
Location: 848421..848672 (252 bp)
Type: Others
Protein ID: WP_001250179.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
AP033_RS03795839380..839682-303WP_000229317.1type II toxin-antitoxin system RelE/ParE family toxin-
AP033_RS03800839670..839927-258WP_000861987.1type II toxin-antitoxin system Phd/YefM family antitoxin-
AP033_RS03805840129..840662-534WP_000118351.1GNAT family N-acetyltransferase-
AP033_RS20035840659..841084-426WP_001882332.1DUF1778 domain-containing protein-
AP033_RS03815841151..841522-372WP_001164080.1nucleotide pyrophosphohydrolase-
AP033_RS03820841770..842030-261WP_032468027.1DUF3709 domain-containing protein-
AP033_RS19075842048..842208-161Protein_742DUF3709 domain-containing protein-
AP033_RS19080842442..842666-225WP_161571222.1DUF3709 domain-containing protein-
AP033_RS19085842996..843106-111WP_076025930.1DUF645 family protein-
AP033_RS03825843491..843793-303WP_000229325.1type II toxin-antitoxin system RelE/ParE family toxinToxin
AP033_RS03830843781..844038-258WP_070961997.1type II toxin-antitoxin system Phd/YefM family antitoxinAntitoxin
AP033_RS03835844511..845491-981WP_000019368.1IS5-like element ISVch5 family transposase-
AP033_RS03840845561..845887-327Protein_748hypothetical protein-
AP033_RS03845846118..846390+273WP_000246253.1DUF1778 domain-containing protein-
AP033_RS03850846387..846884+498WP_000982260.1GNAT family N-acetyltransferase-
AP033_RS03855847087..847239-153WP_001884520.1DUF645 family protein-
AP033_RS03860847561..848016-456WP_001245327.1GNAT family N-acetyltransferase-
AP033_RS03865848144..848431-288WP_000221354.1type II toxin-antitoxin system RelE/ParE family toxin-
AP033_RS03870848421..848672-252WP_001250179.1type II toxin-antitoxin system Phd/YefM family antitoxin-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
flankIS/Tn--844511..845491980
-insideIntegron--829699..942463112764


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-91)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-68)


Sequences

Toxin        


Download         Length: 101 a.a.        Molecular weight: 11710.64 Da        Isoelectric Point: 5.1972

>T57705 WP_000229325.1 NZ_CP013013:c843793-843491 [Vibrio cholerae]
MVEIIWTEPALSDLNDIAEYIALENVVAAKQLVQTVFTKVERLADFPESGRVPPELEHLNYREVVVSPCRVFYKYDDAKV
RILFVMRAERDLRRLMLTKQ

Download         Length: 303 bp

>T57705 NZ_CP013013:c843793-843491 [Vibrio cholerae]
ATGGTTGAAATAATTTGGACGGAGCCGGCTCTATCCGACTTGAATGATATTGCTGAATACATCGCTCTTGAAAATGTCGT
GGCTGCTAAACAACTGGTGCAAACCGTTTTTACAAAAGTTGAACGTTTGGCCGATTTTCCAGAGTCTGGGCGCGTCCCTC
CAGAACTAGAACACCTCAATTATCGTGAAGTCGTTGTAAGTCCGTGTCGTGTTTTCTACAAGTATGATGATGCAAAGGTT
CGTATTCTTTTTGTTATGCGTGCGGAGCGAGATTTGCGTCGGTTAATGCTTACGAAACAGTAG

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9629.12 Da        Isoelectric Point: 7.3178

>AT57705 WP_070961997.1 NZ_CP013013:c844038-843781 [Vibrio cholerae]
MKVELVTSLKRQATKILADLHDTKEPVLITEHGKPSAYLIDVDDYEFMQNRLAILEGIARGERALADGKVVSHQDAKDRI
SKWLK

Download         Length: 258 bp

>AT57705 NZ_CP013013:c844038-843781 [Vibrio cholerae]
ATGAAAGTAGAACTTGTGACGTCACTAAAACGTCAGGCCACTAAGATCCTTGCCGATCTTCATGATACGAAAGAGCCAGT
ATTGATAACTGAGCACGGAAAACCGTCAGCTTACCTTATTGATGTAGACGACTATGAATTTATGCAAAATCGTTTAGCGA
TCTTGGAAGGTATTGCTCGCGGAGAGCGAGCTTTAGCGGATGGTAAAGTGGTCAGCCATCAAGATGCTAAGGACAGAATA
TCAAAATGGTTGAAATAA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References