Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | I | Classification (family/domain) | ralRA/- |
Location | 1393987..1394358 | Replicon | chromosome |
Accession | NZ_CP009789 | ||
Organism | Escherichia coli K-12 strain K-12 ER3413 |
Toxin (Protein)
Gene name | ralR | Uniprot ID | F4VC37 |
Locus tag | ER3413_RS06975 | Protein ID | WP_001317028.1 |
Coordinates | 1394164..1394358 (-) | Length | 65 a.a. |
Antitoxin (RNA)
Gene name | ralA | ||
Locus tag | - | ||
Coordinates | 1393987..1394165 (+) |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
ER3413_RS06950 | 1389942..1391315 | + | 1374 | WP_000123737.1 | ATP-dependent RNA helicase DbpA | - |
ER3413_RS06955 | 1391444..1392379 | - | 936 | WP_001157406.1 | tRNA 2-thiocytidine(32) synthetase TtcA | - |
ER3413_RS23370 | 1392431..1393666 | - | 1236 | WP_000040852.1 | site-specific integrase | - |
ER3413_RS06965 | 1393668..1393883 | - | 216 | WP_000079604.1 | excisionase XisR | - |
ER3413_RS06970 | 1393962..1394171 | - | 210 | WP_000276809.1 | double-strand break reduction protein RcbA | - |
- | 1393987..1394165 | + | 179 | NuclAT_0 | - | Antitoxin |
- | 1393987..1394165 | + | 179 | NuclAT_0 | - | Antitoxin |
- | 1393987..1394165 | + | 179 | NuclAT_0 | - | Antitoxin |
- | 1393987..1394165 | + | 179 | NuclAT_0 | - | Antitoxin |
ER3413_RS06975 | 1394164..1394358 | - | 195 | WP_001317028.1 | type I toxin-antitoxin system endodeoxyribonuclease toxin RalR | Toxin |
ER3413_RS06980 | 1394415..1395224 | - | 810 | WP_000166319.1 | recombination protein RecT | - |
ER3413_RS06985 | 1395217..1397817 | - | 2601 | WP_000105143.1 | exodeoxyribonuclease VIII | - |
ER3413_RS06990 | 1397919..1398194 | - | 276 | WP_000632297.1 | protein RacC | - |
ER3413_RS06995 | 1398269..1398439 | - | 171 | WP_001352098.1 | conserved protein, Rac prophage | - |
ER3413_RS07000 | 1398439..1398660 | - | 222 | WP_000560225.1 | killing protein KilR | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
inside | Prophage | - | - | 1385172..1414104 | 28932 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 65 a.a. Molecular weight: 7018.89 Da Isoelectric Point: 8.9538
>T49785 WP_001317028.1 NZ_CP009789:c1394358-1394164 [Escherichia coli K-12]
MRYDNVKPCPFCGCPSVTVKAISGYYRAKCNGCESRTGYGGSEKEALERWNKRTTGNNNGGVHV
MRYDNVKPCPFCGCPSVTVKAISGYYRAKCNGCESRTGYGGSEKEALERWNKRTTGNNNGGVHV
Download Length: 195 bp
>T49785 NZ_CP009789:c1394358-1394164 [Escherichia coli K-12]
ATGAGATATGACAATGTTAAACCATGTCCATTTTGTGGTTGTCCATCAGTAACGGTGAAAGCCATTTCAGGATATTACCG
AGCGAAGTGTAACGGATGCGAATCCCGAACCGGTTATGGTGGAAGTGAAAAAGAAGCACTCGAAAGATGGAATAAACGAA
CCACTGGAAATAATAATGGAGGTGTTCATGTATAA
ATGAGATATGACAATGTTAAACCATGTCCATTTTGTGGTTGTCCATCAGTAACGGTGAAAGCCATTTCAGGATATTACCG
AGCGAAGTGTAACGGATGCGAATCCCGAACCGGTTATGGTGGAAGTGAAAAAGAAGCACTCGAAAGATGGAATAAACGAA
CCACTGGAAATAATAATGGAGGTGTTCATGTATAA
Antitoxin
Download Length: 179 bp
>AT49785 NZ_CP009789:1393987-1394165 [Escherichia coli K-12]
GAGGACTGAAGTTTCTCGCAATTAAAATTTATCAGTTTTACTTTCTGCTCTCTGGAAACGCCTGCTTCTTTTTTACCTGA
GAGCATTTTTTCGCATTCTGATTTCGTTAGTTTAGATTTTGAATATCTTGTCCAGTTAGTAGGAGTGCCACCTTCCTTTT
CAATAGTGGCGGTAATTTT
GAGGACTGAAGTTTCTCGCAATTAAAATTTATCAGTTTTACTTTCTGCTCTCTGGAAACGCCTGCTTCTTTTTTACCTGA
GAGCATTTTTTCGCATTCTGATTTCGTTAGTTTAGATTTTGAATATCTTGTCCAGTTAGTAGGAGTGCCACCTTCCTTTT
CAATAGTGGCGGTAATTTT
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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