Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | DinJ-YafQ (relBE)/YafQ-DinJ |
Location | 522682..523167 | Replicon | chromosome |
Accession | NZ_LR134331 | ||
Organism | Lacticaseibacillus rhamnosus strain NCTC13764 |
Toxin (Protein)
Gene name | yafQ | Uniprot ID | C2K0Y1 |
Locus tag | EL173_RS02595 | Protein ID | WP_005691636.1 |
Coordinates | 522682..522867 (-) | Length | 62 a.a. |
Antitoxin (Protein)
Gene name | dinJ | Uniprot ID | A0A508YYT1 |
Locus tag | EL173_RS02600 | Protein ID | WP_014571130.1 |
Coordinates | 522895..523167 (-) | Length | 91 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
EL173_RS02570 | 517689..518378 | + | 690 | WP_005691628.1 | rhomboid family intramembrane serine protease | - |
EL173_RS02575 | 518870..519478 | - | 609 | WP_005691630.1 | hypothetical protein | - |
EL173_RS02585 | 519925..520800 | + | 876 | WP_025014074.1 | Rgg/GadR/MutR family transcriptional regulator | - |
EL173_RS02590 | 521043..522458 | - | 1416 | WP_005691634.1 | DNA polymerase III subunit epsilon | - |
EL173_RS02595 | 522682..522867 | - | 186 | WP_005691636.1 | type II toxin-antitoxin system mRNA interferase toxin, RelE/StbE family | Toxin |
EL173_RS02600 | 522895..523167 | - | 273 | WP_014571130.1 | type II toxin-antitoxin system RelB/DinJ family antitoxin | Antitoxin |
EL173_RS02605 | 523729..523977 | + | 249 | WP_005691639.1 | hypothetical protein | - |
EL173_RS02610 | 524220..524513 | + | 294 | WP_005684269.1 | metalloregulator ArsR/SmtB family transcription factor | - |
EL173_RS02615 | 524595..525758 | + | 1164 | WP_005691640.1 | MFS transporter | - |
EL173_RS02620 | 525912..526487 | + | 576 | WP_014571131.1 | DNA-3-methyladenine glycosylase I | - |
EL173_RS02625 | 526630..527226 | + | 597 | WP_005691643.1 | IS607 family transposase | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
inside | Genomic island | - | - | 518870..528892 | 10022 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Structures
Toxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A7X2J6C9 |
Antitoxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A508YYT1 |