Detailed information of TA system
Overview
TA module
| Type | I | Classification (family/domain) | IasE-IsrA/SymE(toxin) |
| Location | 3602107..3602521 | Replicon | chromosome |
| Accession | NZ_CP125220 | ||
| Organism | Salmonella enterica subsp. enterica serovar Enteritidis strain sm140 | ||
Toxin (Protein)
| Gene name | IasE | Uniprot ID | M7RBD3 |
| Locus tag | QK897_RS17740 | Protein ID | WP_000994230.1 |
| Coordinates | 3602264..3602521 (+) | Length | 86 a.a. |
Antitoxin (RNA)
| Gene name | IsrA | ||
| Locus tag | - | ||
| Coordinates | 3602107..3602439 (-) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| QK897_RS17700 | 3597368..3597865 | - | 498 | WP_016695185.1 | Saf-pilin pilus formation protein | - |
| QK897_RS17705 | 3598628..3599198 | - | 571 | Protein_3462 | integrase core domain-containing protein | - |
| QK897_RS17710 | 3599119..3599328 | - | 210 | WP_001676010.1 | hypothetical protein | - |
| QK897_RS17715 | 3599381..3599695 | + | 315 | WP_072100769.1 | SymE family type I addiction module toxin | - |
| QK897_RS17720 | 3599762..3600040 | - | 279 | WP_012543321.1 | hypothetical protein | - |
| QK897_RS17725 | 3600357..3600824 | - | 468 | WP_000828182.1 | sugar tyrosine-protein kinase | - |
| QK897_RS17730 | 3600821..3601138 | - | 318 | WP_001751277.1 | hypothetical protein | - |
| QK897_RS17735 | 3601696..3601929 | - | 234 | WP_124084119.1 | hypothetical protein | - |
| - | 3602107..3602439 | - | 333 | - | - | Antitoxin |
| QK897_RS17740 | 3602264..3602521 | + | 258 | WP_000994230.1 | SymE family type I addiction module toxin | Toxin |
| QK897_RS17745 | 3602587..3603033 | - | 447 | WP_000171102.1 | hypothetical protein | - |
| QK897_RS17750 | 3603030..3606404 | - | 3375 | Protein_3471 | RHS repeat-associated core domain-containing protein | - |
| QK897_RS17755 | 3606404..3606910 | - | 507 | Protein_3472 | hypothetical protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Genomic island | - | - | 3591799..3606326 | 14527 | |
| flank | IS/Tn | - | - | 3598628..3598906 | 278 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 86 a.a. Molecular weight: 9490.94 Da Isoelectric Point: 9.5519
>T281934 WP_000994230.1 NZ_CP125220:3602264-3602521 [Salmonella enterica subsp. enterica serovar Enteritidis]
MNASGVSVRHINSKTHMTTYYSQIPSLHLKGDWLEEAGFKTGRGVTVKISQGCIVLMADSNEEQKLREQLYQAKQVVKGI
KDVLV
MNASGVSVRHINSKTHMTTYYSQIPSLHLKGDWLEEAGFKTGRGVTVKISQGCIVLMADSNEEQKLREQLYQAKQVVKGI
KDVLV
Download Length: 258 bp
Antitoxin
Download Length: 333 bp
>AT281934 NZ_CP125220:c3602439-3602107 [Salmonella enterica subsp. enterica serovar Enteritidis]
TCCGCCATCAGCACAATACACCCCTGTGAAATCTTCACGGTGACGCCGCGCCCGGTCTTAAATCCCGCTTCTTCCAGCCA
GTCGCCCTTAAGATGCAGGCTGGGGATTTGTGAGTAATAGGTGGTCATGTGGGTTTTGCTGTTGATGTGGCGGACGCTGA
CGCCGGAGGCATTCATATTTGCTGACTAAATAAATTCTTAATTATCCGCCGGATGCTGGCTGATTGTGGAGCTCAGGGTG
AGCGAGTATGGGCGCGACATCCTGGCACTGAGCCCCCCTCTCCCCGGCCAGCTCCGGGCGGTGATGAGCAACCGGCTGCC
GGGGCCGTATTTT
TCCGCCATCAGCACAATACACCCCTGTGAAATCTTCACGGTGACGCCGCGCCCGGTCTTAAATCCCGCTTCTTCCAGCCA
GTCGCCCTTAAGATGCAGGCTGGGGATTTGTGAGTAATAGGTGGTCATGTGGGTTTTGCTGTTGATGTGGCGGACGCTGA
CGCCGGAGGCATTCATATTTGCTGACTAAATAAATTCTTAATTATCCGCCGGATGCTGGCTGATTGTGGAGCTCAGGGTG
AGCGAGTATGGGCGCGACATCCTGGCACTGAGCCCCCCTCTCCCCGGCCAGCTCCGGGCGGTGATGAGCAACCGGCTGCC
GGGGCCGTATTTT
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
