Detailed information of TA system
Overview
TA module
| Type | I | Classification (family/domain) | IasE-IsrA/SymE(toxin) |
| Location | 1116050..1116464 | Replicon | chromosome |
| Accession | NZ_CP120322 | ||
| Organism | Salmonella enterica subsp. enterica serovar Enteritidis strain PS_Ent_1_2022 | ||
Toxin (Protein)
| Gene name | IasE | Uniprot ID | M7RBD3 |
| Locus tag | P1705_RS05270 | Protein ID | WP_000994230.1 |
| Coordinates | 1116050..1116307 (-) | Length | 86 a.a. |
Antitoxin (RNA)
| Gene name | IsrA | ||
| Locus tag | - | ||
| Coordinates | 1116132..1116464 (+) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| P1705_RS05255 | 1111661..1112167 | + | 507 | Protein_989 | hypothetical protein | - |
| P1705_RS05260 | 1112167..1115541 | + | 3375 | Protein_990 | RHS repeat-associated core domain-containing protein | - |
| P1705_RS05265 | 1115538..1115984 | + | 447 | WP_000171102.1 | hypothetical protein | - |
| P1705_RS05270 | 1116050..1116307 | - | 258 | WP_000994230.1 | SymE family type I addiction module toxin | Toxin |
| - | 1116132..1116464 | + | 333 | - | - | Antitoxin |
| P1705_RS05275 | 1116642..1116875 | + | 234 | WP_124084119.1 | hypothetical protein | - |
| P1705_RS05280 | 1117433..1117750 | + | 318 | WP_001751277.1 | hypothetical protein | - |
| P1705_RS05285 | 1117747..1118214 | + | 468 | WP_000828182.1 | sugar tyrosine-protein kinase | - |
| P1705_RS05290 | 1118531..1118809 | + | 279 | WP_012543321.1 | hypothetical protein | - |
| P1705_RS05295 | 1118876..1119190 | - | 315 | WP_072100769.1 | SymE family type I addiction module toxin | - |
| P1705_RS05300 | 1119243..1119452 | + | 210 | WP_001676010.1 | hypothetical protein | - |
| P1705_RS05305 | 1119373..1119943 | + | 571 | Protein_999 | integrase core domain-containing protein | - |
| P1705_RS05310 | 1120706..1121203 | + | 498 | WP_016695185.1 | Saf-pilin pilus formation protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| flank | IS/Tn | - | - | 1119665..1119943 | 278 | ||
| - | inside | Genomic island | - | - | 1110746..1128040 | 17294 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 86 a.a. Molecular weight: 9490.94 Da Isoelectric Point: 9.5519
>T274648 WP_000994230.1 NZ_CP120322:c1116307-1116050 [Salmonella enterica subsp. enterica serovar Enteritidis]
MNASGVSVRHINSKTHMTTYYSQIPSLHLKGDWLEEAGFKTGRGVTVKISQGCIVLMADSNEEQKLREQLYQAKQVVKGI
KDVLV
MNASGVSVRHINSKTHMTTYYSQIPSLHLKGDWLEEAGFKTGRGVTVKISQGCIVLMADSNEEQKLREQLYQAKQVVKGI
KDVLV
Download Length: 258 bp
Antitoxin
Download Length: 333 bp
>AT274648 NZ_CP120322:1116132-1116464 [Salmonella enterica subsp. enterica serovar Enteritidis]
TCCGCCATCAGCACAATACACCCCTGTGAAATCTTCACGGTGACGCCGCGCCCGGTCTTAAATCCCGCTTCTTCCAGCCA
GTCGCCCTTAAGATGCAGGCTGGGGATTTGTGAGTAATAGGTGGTCATGTGGGTTTTGCTGTTGATGTGGCGGACGCTGA
CGCCGGAGGCATTCATATTTGCTGACTAAATAAATTCTTAATTATCCGCCGGATGCTGGCTGATTGTGGAGCTCAGGGTG
AGCGAGTATGGGCGCGACATCCTGGCACTGAGCCCCCCTCTCCCCGGCCAGCTCCGGGCGGTGATGAGCAACCGGCTGCC
GGGGCCGTATTTT
TCCGCCATCAGCACAATACACCCCTGTGAAATCTTCACGGTGACGCCGCGCCCGGTCTTAAATCCCGCTTCTTCCAGCCA
GTCGCCCTTAAGATGCAGGCTGGGGATTTGTGAGTAATAGGTGGTCATGTGGGTTTTGCTGTTGATGTGGCGGACGCTGA
CGCCGGAGGCATTCATATTTGCTGACTAAATAAATTCTTAATTATCCGCCGGATGCTGGCTGATTGTGGAGCTCAGGGTG
AGCGAGTATGGGCGCGACATCCTGGCACTGAGCCCCCCTCTCCCCGGCCAGCTCCGGGCGGTGATGAGCAACCGGCTGCC
GGGGCCGTATTTT
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
