Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | yefM-yoeB (relBE)/YoeB-RelB |
Location | 1954689..1955208 | Replicon | chromosome |
Accession | NC_017618 | ||
Organism | Streptococcus suis JS14 |
Toxin (Protein)
Gene name | yoeB | Uniprot ID | A0A2K1SXY6 |
Locus tag | SSUJS14_RS09670 | Protein ID | WP_012775363.1 |
Coordinates | 1954689..1954946 (-) | Length | 86 a.a. |
Antitoxin (Protein)
Gene name | yefM | Uniprot ID | A0A0K2E7Z9 |
Locus tag | SSUJS14_RS09675 | Protein ID | WP_002939010.1 |
Coordinates | 1954948..1955208 (-) | Length | 87 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
SSUJS14_RS09655 | 1951158..1952888 | - | 1731 | WP_012775361.1 | membrane protein | - |
SSUJS14_RS09660 | 1953253..1954161 | - | 909 | WP_079253084.1 | 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))- dimethyltransferase RsmA | - |
SSUJS14_RS09665 | 1954145..1954675 | - | 531 | WP_009910909.1 | DUF1697 domain-containing protein | - |
SSUJS14_RS09670 | 1954689..1954946 | - | 258 | WP_012775363.1 | Txe/YoeB family addiction module toxin | Toxin |
SSUJS14_RS09675 | 1954948..1955208 | - | 261 | WP_002939010.1 | type II toxin-antitoxin system Phd/YefM family antitoxin | Antitoxin |
SSUJS14_RS09680 | 1955284..1955739 | - | 456 | WP_012028534.1 | 8-oxo-dGTP diphosphatase | - |
SSUJS14_RS09685 | 1955746..1956075 | - | 330 | WP_012775364.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
SSUJS14_RS09690 | 1956065..1956352 | - | 288 | WP_012028535.1 | hypothetical protein | - |
SSUJS14_RS09695 | 1956450..1956818 | - | 369 | WP_012775453.1 | hypothetical protein | - |
SSUJS14_RS09700 | 1956811..1957380 | - | 570 | WP_012775366.1 | ribonuclease M5 | - |
SSUJS14_RS09705 | 1957364..1958146 | - | 783 | WP_012028536.1 | TatD family hydrolase | - |
SSUJS14_RS09710 | 1958253..1958390 | - | 138 | WP_002939016.1 | 50S ribosomal protein L34 | - |
SSUJS14_RS09715 | 1958558..1959553 | - | 996 | WP_012775367.1 | protein jag | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
inside | Genomic island | - | - | 1914908..1958146 | 43238 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 86 a.a. Molecular weight: 10346.81 Da Isoelectric Point: 7.2737
>T27117 WP_012775363.1 NC_017618:c1954946-1954689 [Streptococcus suis JS14]
MGIHFTDDAWEDYLYWQGQDKKTLKRINKIIQDMQRHPFEGIAKPEPLKYDYQGAWSRRIDAENRLIYMVEADRLCILSL
KDHYR
MGIHFTDDAWEDYLYWQGQDKKTLKRINKIIQDMQRHPFEGIAKPEPLKYDYQGAWSRRIDAENRLIYMVEADRLCILSL
KDHYR
Download Length: 258 bp
>T27117 NC_017618:c1954946-1954689 [Streptococcus suis JS14]
ATGGGAATCCATTTTACAGACGACGCCTGGGAAGACTATCTTTATTGGCAGGGTCAGGATAAGAAAACACTGAAGAGAAT
CAATAAGATTATCCAGGATATGCAGCGACATCCTTTTGAAGGCATTGCCAAACCAGAACCTTTGAAGTATGATTATCAAG
GTGCCTGGTCTCGGAGAATTGATGCGGAGAATCGGTTGATTTATATGGTGGAAGCTGATCGGTTGTGCATCCTGTCGCTA
AAGGATCATTATAGGTGA
ATGGGAATCCATTTTACAGACGACGCCTGGGAAGACTATCTTTATTGGCAGGGTCAGGATAAGAAAACACTGAAGAGAAT
CAATAAGATTATCCAGGATATGCAGCGACATCCTTTTGAAGGCATTGCCAAACCAGAACCTTTGAAGTATGATTATCAAG
GTGCCTGGTCTCGGAGAATTGATGCGGAGAATCGGTTGATTTATATGGTGGAAGCTGATCGGTTGTGCATCCTGTCGCTA
AAGGATCATTATAGGTGA
Antitoxin
Download Length: 87 a.a. Molecular weight: 9980.36 Da Isoelectric Point: 5.7134
>AT27117 WP_002939010.1 NC_017618:c1955208-1954948 [Streptococcus suis JS14]
MEAIVYSHFRNHLKDYMKKVNDEFEPLVVVNKNPEEDIVVLSKSEWDSLQETLAVARNTYLSQKVLRGMAKVKTGQTQER
NLIEAD
MEAIVYSHFRNHLKDYMKKVNDEFEPLVVVNKNPEEDIVVLSKSEWDSLQETLAVARNTYLSQKVLRGMAKVKTGQTQER
NLIEAD
Download Length: 261 bp
>AT27117 NC_017618:c1955208-1954948 [Streptococcus suis JS14]
ATGGAAGCTATTGTATATTCCCATTTTCGAAATCACTTAAAGGACTATATGAAAAAGGTCAATGACGAGTTTGAACCTTT
GGTCGTGGTTAATAAAAATCCAGAGGAAGATATTGTTGTACTCTCAAAGAGTGAGTGGGATAGTTTACAAGAAACCCTCG
CTGTTGCTCGGAACACTTATCTGTCTCAAAAAGTCCTACGTGGTATGGCTAAAGTCAAAACGGGACAAACCCAAGAACGA
AACCTGATAGAGGCGGACTAA
ATGGAAGCTATTGTATATTCCCATTTTCGAAATCACTTAAAGGACTATATGAAAAAGGTCAATGACGAGTTTGAACCTTT
GGTCGTGGTTAATAAAAATCCAGAGGAAGATATTGTTGTACTCTCAAAGAGTGAGTGGGATAGTTTACAAGAAACCCTCG
CTGTTGCTCGGAACACTTATCTGTCTCAAAAAGTCCTACGTGGTATGGCTAAAGTCAAAACGGGACAAACCCAAGAACGA
AACCTGATAGAGGCGGACTAA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Structures
Toxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A2K1SXY6 |
Antitoxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A0K2E7Z9 |