270705

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) IasE-IsrA/-
Location 3654416..3654836 Replicon chromosome
Accession NZ_CP117348
Organism Salmonella enterica subsp. enterica serovar Heidelberg strain RM101

Toxin (Protein)


Gene name IasE Uniprot ID A0A8E7RAJ3
Locus tag PQQ11_RS17950 Protein ID WP_000994215.1
Coordinates 3654573..3654836 (+) Length 88 a.a.

Antitoxin (RNA)


Gene name IsrA
Locus tag -
Coordinates 3654416..3654826 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PQQ11_RS17915 3650365..3651105 - 741 WP_023170996.1 pili assembly chaperone SafB -
PQQ11_RS17920 3651180..3651677 - 498 WP_023170997.1 Saf-pilin pilus formation protein SafA -
PQQ11_RS17925 3652440..3653144 - 705 Protein_3505 integrase core domain-containing protein -
PQQ11_RS17930 3653197..3653370 + 174 WP_001531381.1 hypothetical protein -
PQQ11_RS17935 3653435..3653902 - 468 WP_001284951.1 Imm42 family immunity protein -
PQQ11_RS17940 3653895..3654203 - 309 WP_165488057.1 hypothetical protein -
PQQ11_RS17945 3654194..3654331 - 138 WP_231391191.1 hypothetical protein -
- 3654416..3654826 - 411 - - Antitoxin
PQQ11_RS17950 3654573..3654836 + 264 WP_000994215.1 hypothetical protein Toxin
PQQ11_RS17955 3654883..3655317 - 435 WP_000789494.1 hypothetical protein -
PQQ11_RS17960 3655314..3659114 - 3801 Protein_3512 RHS repeat-associated core domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 3635633..3679202 43569
flank IS/Tn - - 3652440..3652721 281


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 88 a.a.        Molecular weight: 9458.71 Da        Isoelectric Point: 6.4458

>T270705 WP_000994215.1 NZ_CP117348:3654573-3654836 [Salmonella enterica subsp. enterica serovar Heidelberg]
MNASGASVRHINSETCMTTCYSQIPSGDCQEEAGFETGASVVVKISERGLILIAETDEVRDLRKELYQVKKSMKHIKAGV
NNVVNGN

Download         Length: 264 bp

Antitoxin


Download         Length: 411 bp

>AT270705 NZ_CP117348:c3654826-3654416 [Salmonella enterica subsp. enterica serovar Heidelberg]
TTCACCACATTATTTACCCCCGCCTTAATATGCTTCATCGACTTTTTCACCTGATAAAGCTCCTTCCGTAGATCCCTCAC
TTCATCCGTTTCTGCAATCAGGATCAAACCCCGCTCGGAGATCTTCACAACAACGCTCGCCCCGGTCTCAAATCCCGCTT
CTTCCTGGCAGTCGCCGCTGGGGATTTGTGAGTAACAGGTGGTCATGCAGGTTTCGCTGTTGATGTGGCGGACGCTGGCG
CCGGAGGCATTCATATTTGCTGACTAAATAAATTCTTAATTCTCCGCCGGATGCTGGCTGATTGTGGAGCTCAGGGTGAG
CGAGTATGGGCGCGACATCCTGGCACTGAGCCCCCCTCTCCCCGGCCAGCTCCGGGCGGTGATGAGCAACCGGCTGCCGG
GGCCGTATTTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References