265998

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) IasE-IsrA/SymE(toxin)
Location 3636370..3636784 Replicon chromosome
Accession NZ_CP113540
Organism Salmonella enterica strain CYX

Toxin (Protein)


Gene name IasE Uniprot ID M7RBD3
Locus tag OXV10_RS17975 Protein ID WP_000994230.1
Coordinates 3636527..3636784 (+) Length 86 a.a.

Antitoxin (RNA)


Gene name IsrA
Locus tag -
Coordinates 3636370..3636702 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OXV10_RS17935 3631631..3632128 - 498 WP_016695185.1 Saf-pilin pilus formation protein -
OXV10_RS17940 3632891..3633461 - 571 Protein_3509 integrase core domain-containing protein -
OXV10_RS17945 3633382..3633591 - 210 WP_001676010.1 hypothetical protein -
OXV10_RS17950 3633644..3633958 + 315 WP_072100769.1 SymE family type I addiction module toxin -
OXV10_RS17955 3634025..3634303 - 279 WP_012543321.1 hypothetical protein -
OXV10_RS17960 3634620..3635087 - 468 WP_000828182.1 sugar tyrosine-protein kinase -
OXV10_RS17965 3635084..3635401 - 318 WP_001751277.1 hypothetical protein -
OXV10_RS17970 3635959..3636192 - 234 WP_124084119.1 hypothetical protein -
- 3636370..3636702 - 333 - - Antitoxin
OXV10_RS17975 3636527..3636784 + 258 WP_000994230.1 SymE family type I addiction module toxin Toxin
OXV10_RS17980 3636850..3637296 - 447 WP_000171102.1 hypothetical protein -
OXV10_RS17985 3637293..3640667 - 3375 Protein_3518 RHS domain-containing protein -
OXV10_RS17990 3640667..3641173 - 507 Protein_3519 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 3626062..3640589 14527
flank IS/Tn - - 3632891..3633169 278


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin SymE-like

(14-56)


Sequences

Toxin        


Download         Length: 86 a.a.        Molecular weight: 9490.94 Da        Isoelectric Point: 9.5519

>T265998 WP_000994230.1 NZ_CP113540:3636527-3636784 [Salmonella enterica]
MNASGVSVRHINSKTHMTTYYSQIPSLHLKGDWLEEAGFKTGRGVTVKISQGCIVLMADSNEEQKLREQLYQAKQVVKGI
KDVLV

Download         Length: 258 bp

Antitoxin


Download         Length: 333 bp

>AT265998 NZ_CP113540:c3636702-3636370 [Salmonella enterica]
TCCGCCATCAGCACAATACACCCCTGTGAAATCTTCACGGTGACGCCGCGCCCGGTCTTAAATCCCGCTTCTTCCAGCCA
GTCGCCCTTAAGATGCAGGCTGGGGATTTGTGAGTAATAGGTGGTCATGTGGGTTTTGCTGTTGATGTGGCGGACGCTGA
CGCCGGAGGCATTCATATTTGCTGACTAAATAAATTCTTAATTATCCGCCGGATGCTGGCTGATTGTGGAGCTCAGGGTG
AGCGAGTATGGGCGCGACATCCTGGCACTGAGCCCCCCTCTCCCCGGCCAGCTCCGGGCGGTGATGAGCAACCGGCTGCC
GGGGCCGTATTTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A656IER2

Antitoxin

Download structure file

References