265962

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) IasE-IsrA/SymE(toxin)
Location 3624182..3624614 Replicon chromosome
Accession NZ_CP113538
Organism Salmonella enterica strain XSK

Toxin (Protein)


Gene name IasE Uniprot ID E8XIW0
Locus tag OXV06_RS17650 Protein ID WP_000994224.1
Coordinates 3624339..3624614 (+) Length 92 a.a.

Antitoxin (RNA)


Gene name IsrA
Locus tag -
Coordinates 3624182..3624604 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OXV06_RS17620 3620400..3621137 - 738 WP_001535430.1 pili assembly chaperone SafB -
OXV06_RS17625 3621221..3621733 - 513 WP_077248260.1 pilus assembly protein -
OXV06_RS17630 3622483..3623187 - 705 Protein_3444 integrase core domain-containing protein -
OXV06_RS17635 3623240..3623488 + 249 WP_001738030.1 SymE family type I addiction module toxin -
OXV06_RS17640 3623590..3623898 - 309 WP_010988969.1 hypothetical protein -
OXV06_RS17645 3623981..3624097 - 117 WP_227457392.1 hypothetical protein -
- 3624182..3624604 - 423 - - Antitoxin
OXV06_RS17650 3624339..3624614 + 276 WP_000994224.1 SymE family type I addiction module toxin Toxin
OXV06_RS17655 3624667..3625104 - 438 WP_000943619.1 immunity 26/phosphotriesterase HocA family protein -
OXV06_RS17660 3625667..3626113 - 447 WP_000935097.1 protein SciX -
OXV06_RS17665 3626107..3626976 - 870 Protein_3451 polymorphic toxin type 47 domain-containing protein -
OXV06_RS17670 3627040..3627303 - 264 WP_000932531.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Genomic island - - 3615654..3627303 11649
flank IS/Tn - - 3622483..3622764 281
inside Genomic island - - 3613330..3627303 13973


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin SymE-like

(14-57)


Sequences

Toxin        


Download         Length: 92 a.a.        Molecular weight: 10032.36 Da        Isoelectric Point: 6.4704

>T265962 WP_000994224.1 NZ_CP113538:3624339-3624614 [Salmonella enterica]
MNASGVSVRHINSETCMTACYSQIPSQHLKGDWQEEAGFETGHGVTVKISEGCLILIAETDEVRDLRKELYQVKKSMKHI
KAGVNNVVNGD

Download         Length: 276 bp

Antitoxin


Download         Length: 423 bp

>AT265962 NZ_CP113538:c3624604-3624182 [Salmonella enterica]
TTCACCACATTATTTACCCCCGCCTTAATATGCTTCATCGACTTTTTCACCTGATAAAGCTCCTTCCGTAGATCCCTCAC
TTCGTCCGTCTCTGCAATCAGGATCAAACACCCCTCGGAGATCTTCACGGTGACGCCGTGCCCGGTCTCAAATCCCGCTT
CTTCCTGCCAGTCACCCTTAAGGTGCTGGCTGGGGATTTGTGAGTAACAGGCGGTCATGCAGGTTTCGCTGTTGATATGG
CGGACGCTGACGCCGGAGGCATTCATATTTGCTGACTAAATAAATTCTTATTTATCCGCCGGATGCTGGCTGATTGTGGA
GCTCAGGGTGAGTGAGTATGGGCGCGACATCCTGGCACCGCGCCTCCCTCTCCCCGGCCAGCCCCGGCCGGTGATGAGCA
GCCGGCTGCCGGGGCCGTATTTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A3V2JPW5

Antitoxin

Download structure file

References