264096

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) IasE-IsrA/SymE(toxin)
Location 3315700..3316132 Replicon chromosome
Accession NZ_CP110657
Organism Salmonella enterica subsp. enterica strain S2122

Toxin (Protein)


Gene name IasE Uniprot ID E8XIW0
Locus tag OOK64_RS16080 Protein ID WP_000994224.1
Coordinates 3315700..3315975 (-) Length 92 a.a.

Antitoxin (RNA)


Gene name IsrA
Locus tag -
Coordinates 3315710..3316132 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OOK64_RS16060 3313011..3313274 + 264 WP_000932531.1 hypothetical protein -
OOK64_RS16065 3313338..3314207 + 870 Protein_3125 polymorphic toxin type 47 domain-containing protein -
OOK64_RS16070 3314201..3314647 + 447 WP_000935097.1 protein SciX -
OOK64_RS16075 3315210..3315647 + 438 WP_000943619.1 immunity 26/phosphotriesterase HocA family protein -
OOK64_RS16080 3315700..3315975 - 276 WP_000994224.1 SymE family type I addiction module toxin Toxin
- 3315710..3316132 + 423 - - Antitoxin
OOK64_RS16085 3316160..3316333 + 174 WP_088131292.1 RHS repeat-associated core domain-containing protein -
OOK64_RS16090 3316416..3316724 + 309 WP_010988969.1 hypothetical protein -
OOK64_RS16095 3316826..3317074 - 249 WP_001738030.1 SymE family type I addiction module toxin -
OOK64_RS16100 3317127..3317831 + 705 Protein_3132 integrase core domain-containing protein -
OOK64_RS16105 3318581..3319093 + 513 WP_077248260.1 pilus assembly protein -
OOK64_RS16110 3319177..3319914 + 738 WP_001535430.1 pili assembly chaperone SafB -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Genomic island - - 3313434..3327722 14288
flank IS/Tn - - 3317550..3317831 281


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin SymE-like

(14-57)


Sequences

Toxin        


Download         Length: 92 a.a.        Molecular weight: 10032.36 Da        Isoelectric Point: 6.4704

>T264096 WP_000994224.1 NZ_CP110657:c3315975-3315700 [Salmonella enterica subsp. enterica]
MNASGVSVRHINSETCMTACYSQIPSQHLKGDWQEEAGFETGHGVTVKISEGCLILIAETDEVRDLRKELYQVKKSMKHI
KAGVNNVVNGD

Download         Length: 276 bp

Antitoxin


Download         Length: 423 bp

>AT264096 NZ_CP110657:3315710-3316132 [Salmonella enterica subsp. enterica]
TTCACCACATTATTTACCCCCGCCTTAATATGCTTCATCGACTTTTTCACCTGATAAAGCTCCTTCCGTAGATCCCTCAC
TTCGTCCGTCTCTGCAATCAGGATCAAACACCCCTCGGAGATCTTCACGGTGACGCCGTGCCCGGTCTCAAATCCCGCTT
CTTCCTGCCAGTCACCCTTAAGGTGCTGGCTGGGGATTTGTGAGTAACAGGCGGTCATGCAGGTTTCGCTGTTGATATGG
CGGACGCTGACGCCGGAGGCATTCATATTTGCTGACTAAATAAATTCTTATTTATCCGCCGGATGCTGGCTGATTGTGGA
GCTCAGGGTGAGTGAGTATGGGCGCGACATCCTGGCACCGCGCCTCCCTCTCCCCGGCCAGCCCCGGCCGGTGATGAGCA
GCCGGCTGCCGGGGCCGTATTTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A3V2JPW5

Antitoxin

Download structure file

References