258085

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) IasE-IsrA/SymE(toxin)
Location 3697695..3698127 Replicon chromosome
Accession NZ_CP104484
Organism Salmonella enterica strain SalSpp_sample_07_No.3

Toxin (Protein)


Gene name IasE Uniprot ID E8XIW0
Locus tag N4231_RS18275 Protein ID WP_000994224.1
Coordinates 3697852..3698127 (+) Length 92 a.a.

Antitoxin (RNA)


Gene name IsrA
Locus tag -
Coordinates 3697695..3698117 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N4231_RS18245 3693913..3694650 - 738 WP_001535430.1 pili assembly chaperone SafB -
N4231_RS18250 3694734..3695246 - 513 WP_077248260.1 pilus assembly protein -
N4231_RS18255 3695996..3696700 - 705 Protein_3571 integrase core domain-containing protein -
N4231_RS18260 3696753..3697001 + 249 WP_001738030.1 SymE family type I addiction module toxin -
N4231_RS18265 3697103..3697411 - 309 WP_010988969.1 hypothetical protein -
N4231_RS18270 3697494..3697610 - 117 WP_227457392.1 hypothetical protein -
- 3697695..3698117 - 423 - - Antitoxin
N4231_RS18275 3697852..3698127 + 276 WP_000994224.1 SymE family type I addiction module toxin Toxin
N4231_RS18280 3698180..3698617 - 438 WP_000943619.1 immunity 26/phosphotriesterase HocA family protein -
N4231_RS18285 3699180..3699626 - 447 WP_000935097.1 protein SciX -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Genomic island - - 3686843..3699626 12783
flank IS/Tn - - 3695996..3696277 281


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin SymE-like

(14-57)


Sequences

Toxin        


Download         Length: 92 a.a.        Molecular weight: 10032.36 Da        Isoelectric Point: 6.4704

>T258085 WP_000994224.1 NZ_CP104484:3697852-3698127 [Salmonella enterica]
MNASGVSVRHINSETCMTACYSQIPSQHLKGDWQEEAGFETGHGVTVKISEGCLILIAETDEVRDLRKELYQVKKSMKHI
KAGVNNVVNGD

Download         Length: 276 bp

Antitoxin


Download         Length: 423 bp

>AT258085 NZ_CP104484:c3698117-3697695 [Salmonella enterica]
TTCACCACATTATTTACCCCCGCCTTAATATGCTTCATCGACTTTTTCACCTGATAAAGCTCCTTCCGTAGATCCCTCAC
TTCGTCCGTCTCTGCAATCAGGATCAAACACCCCTCGGAGATCTTCACGGTGACGCCGTGCCCGGTCTCAAATCCCGCTT
CTTCCTGCCAGTCACCCTTAAGGTGCTGGCTGGGGATTTGTGAGTAACAGGCGGTCATGCAGGTTTCGCTGTTGATATGG
CGGACGCTGACGCCGGAGGCATTCATATTTGCTGACTAAATAAATTCTTATTTATCCGCCGGATGCTGGCTGATTGTGGA
GCTCAGGGTGAGTGAGTATGGGCGCGACATCCTGGCACCGCGCCTCCCTCTCCCCGGCCAGCCCCGGCCGGTGATGAGCA
GCCGGCTGCCGGGGCCGTATTTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A3V2JPW5

Antitoxin

Download structure file

References