Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | IV | Classification (family/domain) | yeeUV (cbtA-cbeA)/CbtA-CbeA |
Location | 3298768..3299448 | Replicon | chromosome |
Accession | NZ_CP104025 | ||
Organism | Erwinia amylovora strain Ea915 |
Toxin (Protein)
Gene name | yeeV | Uniprot ID | D4HV69 |
Locus tag | MTP51_RS14965 | Protein ID | WP_004155189.1 |
Coordinates | 3298768..3299088 (-) | Length | 107 a.a. |
Antitoxin (Protein)
Gene name | yeeU | Uniprot ID | D4HV68 |
Locus tag | MTP51_RS14970 | Protein ID | WP_004155188.1 |
Coordinates | 3299125..3299448 (-) | Length | 108 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
MTP51_RS14945 (MTP51_14945) | 3296579..3296779 | - | 201 | Protein_2878 | transposase | - |
MTP51_RS14950 (MTP51_14950) | 3297198..3297473 | - | 276 | WP_004155192.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
MTP51_RS14955 (MTP51_14955) | 3297477..3297725 | - | 249 | WP_004155191.1 | ribbon-helix-helix domain-containing protein | - |
MTP51_RS14960 (MTP51_14960) | 3297822..3298655 | - | 834 | WP_004155190.1 | DUF4942 domain-containing protein | - |
MTP51_RS14965 (MTP51_14965) | 3298768..3299088 | - | 321 | WP_004155189.1 | TA system toxin CbtA family protein | Toxin |
MTP51_RS14970 (MTP51_14970) | 3299125..3299448 | - | 324 | WP_004155188.1 | type IV toxin-antitoxin system YeeU family antitoxin | Antitoxin |
MTP51_RS14975 (MTP51_14975) | 3299461..3299931 | - | 471 | WP_004155187.1 | DNA repair protein RadC | - |
MTP51_RS14980 (MTP51_14980) | 3300002..3300576 | - | 575 | Protein_2885 | DUF945 domain-containing protein | - |
MTP51_RS14985 (MTP51_14985) | 3300801..3301043 | - | 243 | WP_004155184.1 | hypothetical protein | - |
MTP51_RS14990 (MTP51_14990) | 3302253..3302450 | + | 198 | WP_004155182.1 | AlpA family phage regulatory protein | - |
MTP51_RS14995 (MTP51_14995) | 3302558..3302908 | + | 351 | WP_004155181.1 | hypothetical protein | - |
MTP51_RS15000 (MTP51_15000) | 3303352..3304437 | + | 1086 | WP_004155179.1 | DNA sulfur modification protein DndB | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
inside | Genomic island | - | - | 3297198..3320356 | 23158 | ||
flank | IS/Tn | - | - | 3296555..3296779 | 224 | ||
inside | Genomic island | - | - | 3297477..3320356 | 22879 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 107 a.a. Molecular weight: 12023.69 Da Isoelectric Point: 5.4732
>T257041 WP_004155189.1 NZ_CP104025:c3299088-3298768 [Erwinia amylovora]
MHISTVPATVPVSSRLSPVQVWQQLLTYLLEHHYGLTLNDTPFHDDAAIEEHIDAGITLADAVNFLVERYELVRIDRKGF
TWQEQTPFLAATDILRARRATGLINI
MHISTVPATVPVSSRLSPVQVWQQLLTYLLEHHYGLTLNDTPFHDDAAIEEHIDAGITLADAVNFLVERYELVRIDRKGF
TWQEQTPFLAATDILRARRATGLINI
Download Length: 321 bp
Antitoxin
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Structures
Toxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A831EPU6 |
Antitoxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A831ENV6 |