Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | I | Classification (family/domain) | IasE-IsrA/SymE(toxin) |
Location | 3724585..3725017 | Replicon | chromosome |
Accession | NZ_CP101379 | ||
Organism | Salmonella enterica strain SC2016290 |
Toxin (Protein)
Gene name | IasE | Uniprot ID | E8XIW0 |
Locus tag | NMU35_RS18500 | Protein ID | WP_000994224.1 |
Coordinates | 3724742..3725017 (+) | Length | 92 a.a. |
Antitoxin (RNA)
Gene name | IsrA | ||
Locus tag | - | ||
Coordinates | 3724585..3725007 (-) |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
NMU35_RS18470 | 3720803..3721540 | - | 738 | WP_001535430.1 | pili assembly chaperone SafB | - |
NMU35_RS18475 | 3721624..3722136 | - | 513 | WP_077248260.1 | pilus assembly protein | - |
NMU35_RS18480 | 3722886..3723590 | - | 705 | Protein_3615 | integrase core domain-containing protein | - |
NMU35_RS18485 | 3723643..3723891 | + | 249 | WP_001738030.1 | SymE family type I addiction module toxin | - |
NMU35_RS18490 | 3723993..3724301 | - | 309 | WP_010988969.1 | hypothetical protein | - |
NMU35_RS18495 | 3724384..3724500 | - | 117 | WP_227457392.1 | hypothetical protein | - |
- | 3724585..3725007 | - | 423 | - | - | Antitoxin |
NMU35_RS18500 | 3724742..3725017 | + | 276 | WP_000994224.1 | SymE family type I addiction module toxin | Toxin |
NMU35_RS18505 | 3725070..3725507 | - | 438 | WP_000943619.1 | immunity 26/phosphotriesterase HocA family protein | - |
NMU35_RS18510 | 3726070..3726516 | - | 447 | WP_000935097.1 | protein SciX | - |
NMU35_RS18515 | 3726510..3727379 | - | 870 | Protein_3622 | polymorphic toxin type 47 domain-containing protein | - |
NMU35_RS18520 | 3727443..3727706 | - | 264 | WP_000932531.1 | hypothetical protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
inside | Genomic island | - | - | 3713733..3727706 | 13973 | ||
flank | IS/Tn | - | - | 3722886..3723167 | 281 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 92 a.a. Molecular weight: 10032.36 Da Isoelectric Point: 6.4704
>T252042 WP_000994224.1 NZ_CP101379:3724742-3725017 [Salmonella enterica]
MNASGVSVRHINSETCMTACYSQIPSQHLKGDWQEEAGFETGHGVTVKISEGCLILIAETDEVRDLRKELYQVKKSMKHI
KAGVNNVVNGD
MNASGVSVRHINSETCMTACYSQIPSQHLKGDWQEEAGFETGHGVTVKISEGCLILIAETDEVRDLRKELYQVKKSMKHI
KAGVNNVVNGD
Download Length: 276 bp
Antitoxin
Download Length: 423 bp
>AT252042 NZ_CP101379:c3725007-3724585 [Salmonella enterica]
TTCACCACATTATTTACCCCCGCCTTAATATGCTTCATCGACTTTTTCACCTGATAAAGCTCCTTCCGTAGATCCCTCAC
TTCGTCCGTCTCTGCAATCAGGATCAAACACCCCTCGGAGATCTTCACGGTGACGCCGTGCCCGGTCTCAAATCCCGCTT
CTTCCTGCCAGTCACCCTTAAGGTGCTGGCTGGGGATTTGTGAGTAACAGGCGGTCATGCAGGTTTCGCTGTTGATATGG
CGGACGCTGACGCCGGAGGCATTCATATTTGCTGACTAAATAAATTCTTATTTATCCGCCGGATGCTGGCTGATTGTGGA
GCTCAGGGTGAGTGAGTATGGGCGCGACATCCTGGCACCGCGCCTCCCTCTCCCCGGCCAGCCCCGGCCGGTGATGAGCA
GCCGGCTGCCGGGGCCGTATTTT
TTCACCACATTATTTACCCCCGCCTTAATATGCTTCATCGACTTTTTCACCTGATAAAGCTCCTTCCGTAGATCCCTCAC
TTCGTCCGTCTCTGCAATCAGGATCAAACACCCCTCGGAGATCTTCACGGTGACGCCGTGCCCGGTCTCAAATCCCGCTT
CTTCCTGCCAGTCACCCTTAAGGTGCTGGCTGGGGATTTGTGAGTAACAGGCGGTCATGCAGGTTTCGCTGTTGATATGG
CGGACGCTGACGCCGGAGGCATTCATATTTGCTGACTAAATAAATTCTTATTTATCCGCCGGATGCTGGCTGATTGTGGA
GCTCAGGGTGAGTGAGTATGGGCGCGACATCCTGGCACCGCGCCTCCCTCTCCCCGGCCAGCCCCGGCCGGTGATGAGCA
GCCGGCTGCCGGGGCCGTATTTT
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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