Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | I | Classification (family/domain) | IasE-IsrA/SymE(toxin) |
Location | 3706118..3706550 | Replicon | chromosome |
Accession | NZ_CP091569 | ||
Organism | Salmonella enterica strain 131 |
Toxin (Protein)
Gene name | IasE | Uniprot ID | E8XIW0 |
Locus tag | INN75_RS18340 | Protein ID | WP_000994224.1 |
Coordinates | 3706275..3706550 (+) | Length | 92 a.a. |
Antitoxin (RNA)
Gene name | IsrA | ||
Locus tag | - | ||
Coordinates | 3706118..3706540 (-) |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
INN75_RS18310 | 3702336..3703073 | - | 738 | WP_001535430.1 | pili assembly chaperone SafB | - |
INN75_RS18315 | 3703157..3703669 | - | 513 | WP_077248260.1 | pilus assembly protein | - |
INN75_RS18320 | 3704419..3705123 | - | 705 | Protein_3589 | integrase core domain-containing protein | - |
INN75_RS18325 | 3705176..3705424 | + | 249 | WP_001738030.1 | SymE family type I addiction module toxin | - |
INN75_RS18330 | 3705526..3705834 | - | 309 | WP_010988969.1 | hypothetical protein | - |
INN75_RS18335 | 3705917..3706033 | - | 117 | WP_227457392.1 | hypothetical protein | - |
- | 3706118..3706540 | - | 423 | - | - | Antitoxin |
INN75_RS18340 | 3706275..3706550 | + | 276 | WP_000994224.1 | SymE family type I addiction module toxin | Toxin |
INN75_RS18345 | 3706603..3707040 | - | 438 | WP_000943619.1 | immunity 26/phosphotriesterase HocA family protein | - |
INN75_RS18350 | 3707603..3708049 | - | 447 | WP_000935097.1 | protein SciX | - |
INN75_RS18355 | 3708043..3708912 | - | 870 | Protein_3596 | polymorphic toxin type 47 domain-containing protein | - |
INN75_RS18360 | 3708976..3709239 | - | 264 | WP_000932531.1 | hypothetical protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
inside | Genomic island | - | - | 3695266..3709239 | 13973 | ||
flank | IS/Tn | - | - | 3704419..3704700 | 281 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 92 a.a. Molecular weight: 10032.36 Da Isoelectric Point: 6.4704
>T233846 WP_000994224.1 NZ_CP091569:3706275-3706550 [Salmonella enterica]
MNASGVSVRHINSETCMTACYSQIPSQHLKGDWQEEAGFETGHGVTVKISEGCLILIAETDEVRDLRKELYQVKKSMKHI
KAGVNNVVNGD
MNASGVSVRHINSETCMTACYSQIPSQHLKGDWQEEAGFETGHGVTVKISEGCLILIAETDEVRDLRKELYQVKKSMKHI
KAGVNNVVNGD
Download Length: 276 bp
>T233846 NZ_LN831039:c727206-726775 [Mycolicibacterium smegmatis]
ATGTTCCTGCTAGACGTGAACGTCGTACTTGCGGCATACCGCGCAGACCACCCAGATCACGCCACCGTGCGTCCGTGGTT
CGATCGCCTGCTCGATGGCGACGGACCGTTCACCGTCCCGGTACAGGTGTGGGCGTCGTTCCTGCGATTGGTAACCAATC
GGCGTATCTTCCCAGTCCCCACACCCCGTGACGATGCGTTCGCGTTCATCGAAGCCGTCAACGGCCAACCGCACCACGTG
CCGGTAAGCGCGGGCCCGCGGCACCTTGCGCTGCTGCACCAACTTTGCGACGAAGGCGATGCCTCCGGCGACCTGATCCC
CGATGCAGTGCTCGCGGCCATCGCCCACGAACATCATTGCGACGTGGCGACTCTCGATCGGGACTTCGCCCGATTCACCA
CGGTCCGTCATCTGAGGCCGAGTCTGGACTGA
ATGTTCCTGCTAGACGTGAACGTCGTACTTGCGGCATACCGCGCAGACCACCCAGATCACGCCACCGTGCGTCCGTGGTT
CGATCGCCTGCTCGATGGCGACGGACCGTTCACCGTCCCGGTACAGGTGTGGGCGTCGTTCCTGCGATTGGTAACCAATC
GGCGTATCTTCCCAGTCCCCACACCCCGTGACGATGCGTTCGCGTTCATCGAAGCCGTCAACGGCCAACCGCACCACGTG
CCGGTAAGCGCGGGCCCGCGGCACCTTGCGCTGCTGCACCAACTTTGCGACGAAGGCGATGCCTCCGGCGACCTGATCCC
CGATGCAGTGCTCGCGGCCATCGCCCACGAACATCATTGCGACGTGGCGACTCTCGATCGGGACTTCGCCCGATTCACCA
CGGTCCGTCATCTGAGGCCGAGTCTGGACTGA
Antitoxin
Download Length: 423 bp
>AT233846 NZ_CP091569:c3706540-3706118 [Salmonella enterica]
TTCACCACATTATTTACCCCCGCCTTAATATGCTTCATCGACTTTTTCACCTGATAAAGCTCCTTCCGTAGATCCCTCAC
TTCGTCCGTCTCTGCAATCAGGATCAAACACCCCTCGGAGATCTTCACGGTGACGCCGTGCCCGGTCTCAAATCCCGCTT
CTTCCTGCCAGTCACCCTTAAGGTGCTGGCTGGGGATTTGTGAGTAACAGGCGGTCATGCAGGTTTCGCTGTTGATATGG
CGGACGCTGACGCCGGAGGCATTCATATTTGCTGACTAAATAAATTCTTATTTATCCGCCGGATGCTGGCTGATTGTGGA
GCTCAGGGTGAGTGAGTATGGGCGCGACATCCTGGCACCGCGCCTCCCTCTCCCCGGCCAGCCCCGGCCGGTGATGAGCA
GCCGGCTGCCGGGGCCGTATTTT
TTCACCACATTATTTACCCCCGCCTTAATATGCTTCATCGACTTTTTCACCTGATAAAGCTCCTTCCGTAGATCCCTCAC
TTCGTCCGTCTCTGCAATCAGGATCAAACACCCCTCGGAGATCTTCACGGTGACGCCGTGCCCGGTCTCAAATCCCGCTT
CTTCCTGCCAGTCACCCTTAAGGTGCTGGCTGGGGATTTGTGAGTAACAGGCGGTCATGCAGGTTTCGCTGTTGATATGG
CGGACGCTGACGCCGGAGGCATTCATATTTGCTGACTAAATAAATTCTTATTTATCCGCCGGATGCTGGCTGATTGTGGA
GCTCAGGGTGAGTGAGTATGGGCGCGACATCCTGGCACCGCGCCTCCCTCTCCCCGGCCAGCCCCGGCCGGTGATGAGCA
GCCGGCTGCCGGGGCCGTATTTT
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|