Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | I | Classification (family/domain) | IasE-IsrA/SymE(toxin) |
Location | 773846..774260 | Replicon | chromosome |
Accession | NZ_CP085806 | ||
Organism | Salmonella enterica subsp. enterica serovar Enteritidis strain Marill |
Toxin (Protein)
Gene name | IasE | Uniprot ID | M7RBD3 |
Locus tag | LJF46_RS03570 | Protein ID | WP_000994230.1 |
Coordinates | 773846..774103 (-) | Length | 86 a.a. |
Antitoxin (RNA)
Gene name | IsrA | ||
Locus tag | - | ||
Coordinates | 773928..774260 (+) |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
LJF46_RS03555 | 769457..769963 | + | 507 | Protein_680 | phage late control D family protein | - |
LJF46_RS03560 | 769963..773337 | + | 3375 | Protein_681 | RHS domain-containing protein | - |
LJF46_RS03565 | 773334..773780 | + | 447 | WP_000171102.1 | hypothetical protein | - |
LJF46_RS03570 | 773846..774103 | - | 258 | WP_000994230.1 | SymE family type I addiction module toxin | Toxin |
- | 773928..774260 | + | 333 | - | - | Antitoxin |
LJF46_RS03575 | 774438..774671 | + | 234 | WP_124084119.1 | hypothetical protein | - |
LJF46_RS03580 | 775229..775546 | + | 318 | WP_001751277.1 | hypothetical protein | - |
LJF46_RS03585 | 775543..776010 | + | 468 | WP_000828182.1 | sugar tyrosine-protein kinase | - |
LJF46_RS03590 | 776327..776605 | + | 279 | WP_012543321.1 | hypothetical protein | - |
LJF46_RS03595 | 776672..776986 | - | 315 | WP_072100769.1 | SymE family type I addiction module toxin | - |
LJF46_RS03600 | 777039..777248 | + | 210 | WP_001676010.1 | hypothetical protein | - |
LJF46_RS03605 | 777169..777739 | + | 571 | Protein_690 | integrase core domain-containing protein | - |
LJF46_RS03610 | 778502..778999 | + | 498 | WP_016695185.1 | Saf-pilin pilus formation protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
- | inside | Genomic island | - | - | 768542..787633 | 19091 | |
flank | IS/Tn | - | - | 777461..777739 | 278 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 86 a.a. Molecular weight: 9490.94 Da Isoelectric Point: 9.5519
>T221672 WP_000994230.1 NZ_CP085806:c774103-773846 [Salmonella enterica subsp. enterica serovar Enteritidis]
MNASGVSVRHINSKTHMTTYYSQIPSLHLKGDWLEEAGFKTGRGVTVKISQGCIVLMADSNEEQKLREQLYQAKQVVKGI
KDVLV
MNASGVSVRHINSKTHMTTYYSQIPSLHLKGDWLEEAGFKTGRGVTVKISQGCIVLMADSNEEQKLREQLYQAKQVVKGI
KDVLV
Download Length: 258 bp
>T221672 NZ_CP117563:c40837-40550 [Escherichia albertii]
ATGACTTATACGGTAAAATTCAGGGATGATGCGCTCAAAGAATGGCTGAAACTGGATAAATCCATTCAGCAACAGTTCGC
AAAAAAACTAAAAAAATGCAGCGAAAATCCTCATATACCTTCAGCAAAACTACGTGAACTAAAAAATTGCTACAAAATCA
AACTTCGTGCATCGGGTTTTCGTCTGGTCTATCAGGTTATTGATGACATGTTAATTATTGCGGTTGTCGCAGTAGGTAAA
CGTGAACGTAGTAACGTTTATAATCTTGCCAGTGAGAGAATGAGATAG
ATGACTTATACGGTAAAATTCAGGGATGATGCGCTCAAAGAATGGCTGAAACTGGATAAATCCATTCAGCAACAGTTCGC
AAAAAAACTAAAAAAATGCAGCGAAAATCCTCATATACCTTCAGCAAAACTACGTGAACTAAAAAATTGCTACAAAATCA
AACTTCGTGCATCGGGTTTTCGTCTGGTCTATCAGGTTATTGATGACATGTTAATTATTGCGGTTGTCGCAGTAGGTAAA
CGTGAACGTAGTAACGTTTATAATCTTGCCAGTGAGAGAATGAGATAG
Antitoxin
Download Length: 333 bp
>AT221672 NZ_CP085806:773928-774260 [Salmonella enterica subsp. enterica serovar Enteritidis]
TCCGCCATCAGCACAATACACCCCTGTGAAATCTTCACGGTGACGCCGCGCCCGGTCTTAAATCCCGCTTCTTCCAGCCA
GTCGCCCTTAAGATGCAGGCTGGGGATTTGTGAGTAATAGGTGGTCATGTGGGTTTTGCTGTTGATGTGGCGGACGCTGA
CGCCGGAGGCATTCATATTTGCTGACTAAATAAATTCTTAATTATCCGCCGGATGCTGGCTGATTGTGGAGCTCAGGGTG
AGCGAGTATGGGCGCGACATCCCGGCACTGAGCCCCCCTCTCCCCGGCCAGCTCCGGGCGGTGATGAGCAACCGGCTGCC
GGGGCCGTATTTT
TCCGCCATCAGCACAATACACCCCTGTGAAATCTTCACGGTGACGCCGCGCCCGGTCTTAAATCCCGCTTCTTCCAGCCA
GTCGCCCTTAAGATGCAGGCTGGGGATTTGTGAGTAATAGGTGGTCATGTGGGTTTTGCTGTTGATGTGGCGGACGCTGA
CGCCGGAGGCATTCATATTTGCTGACTAAATAAATTCTTAATTATCCGCCGGATGCTGGCTGATTGTGGAGCTCAGGGTG
AGCGAGTATGGGCGCGACATCCCGGCACTGAGCCCCCCTCTCCCCGGCCAGCTCCGGGCGGTGATGAGCAACCGGCTGCC
GGGGCCGTATTTT
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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